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2KEM

Extended structure of citidine deaminase domain of APOBEC3G

Summary for 2KEM
Entry DOI10.2210/pdb2kem/pdb
Related2JYW 2kbo 3E1U
DescriptorDNA dC->dU-editing enzyme APOBEC-3G, ZINC ION (2 entities in total)
Functional Keywordshelix, sheet, zinc, alternative splicing, antiviral defense, cytoplasm, host-virus interaction, hydrolase, metal-binding, nucleus, polymorphism, ubl conjugation
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: Q9HC16
Total number of polymer chains1
Total formula weight23579.87
Authors
Harjes, E.,Gross, P.J.,Chen, K.,Lu, Y.,Shindo, K.,Nowarski, R.,Gross, J.D.,Kotler, M.,Harris, R.S.,Matsuo, H. (deposition date: 2009-01-30, release date: 2009-06-02, Last modification date: 2021-11-10)
Primary citationHarjes, E.,Gross, P.J.,Chen, K.M.,Lu, Y.,Shindo, K.,Nowarski, R.,Gross, J.D.,Kotler, M.,Harris, R.S.,Matsuo, H.
An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model
J.Mol.Biol., 389:819-832, 2009
Cited by
PubMed: 19389408
DOI: 10.1016/j.jmb.2009.04.031
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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