5KEG

Crystal structure of APOBEC3A in complex with a single-stranded DNA

Summary for 5KEG

• Entry DOI: 10.2210/pdb5keg/pdb
• Descriptor: DNA dC->dU-editing enzyme APOBEC-3A, DNA (5'-D(*TP*TP*CP*TP*T)-3'), ZINC ION, ... (6 entities in total)
• Functional Keywords: apobec3a, dna cytidine deaminase complex with a substrate dna, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 27944.14

Authors

Kouno, T.,Hilbert, B.J.,Silvas, T.,Royer, W.E.,Matsuo, H.,Schiffer, C.A. (deposition date: 2016-06-09, release date: 2017-05-10, Last modification date: 2023-09-27)

• Primary citation: Kouno, T.,Silvas, T.V.,Hilbert, B.J.,Shandilya, S.M.D.,Bohn, M.F.,Kelch, B.A.,Royer, W.E.,Somasundaran, M.,Kurt Yilmaz, N.,Matsuo, H.,Schiffer, C.A.; Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.; Nat Commun, 8:15024-15024, 2017; PubMed: 28452355; DOI: 10.1038/ncomms15024

Experimental method

X-RAY DIFFRACTION (2.2 Å)