1BET
| NEW PROTEIN FOLD REVEALED BY A 2.3 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF NERVE GROWTH FACTOR | Descriptor: | BETA-NERVE GROWTH FACTOR | Authors: | Mcdonald, N.Q, Lapatto, R, Murray-Rust, J, Gunning, J, Wlodawer, A, Blundell, T.L. | Deposit date: | 1993-04-08 | Release date: | 1994-05-31 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor. Nature, 354, 1991
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1BND
| STRUCTURE OF THE BRAIN-DERIVED NEUROTROPHIC FACTOR(SLASH)NEUROTROPHIN 3 HETERODIMER | Descriptor: | BRAIN DERIVED NEUROTROPHIC FACTOR, ISOPROPYL ALCOHOL, NEUROTROPHIN 3 | Authors: | Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y. | Deposit date: | 1994-12-12 | Release date: | 1996-04-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer. Biochemistry, 34, 1995
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1BTG
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1SGF
| CRYSTAL STRUCTURE OF 7S NGF: A COMPLEX OF NERVE GROWTH FACTOR WITH FOUR BINDING PROTEINS (SERINE PROTEINASES) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NERVE GROWTH FACTOR, ... | Authors: | Bax, B.D.V, Blundell, T.L, Murray-Rust, J, Mcdonald, N.Q. | Deposit date: | 1997-08-08 | Release date: | 1998-05-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins. Structure, 5, 1997
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1B8K
| Neurotrophin-3 from Human | Descriptor: | PROTEIN (NEUROTROPHIN-3) | Authors: | Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S. | Deposit date: | 1999-02-01 | Release date: | 1999-02-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site. Protein Sci., 8, 1999
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1B8M
| BRAIN DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN-4 | Descriptor: | PROTEIN (BRAIN DERIVED NEUROTROPHIC FACTOR), PROTEIN (NEUROTROPHIN-4) | Authors: | Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S. | Deposit date: | 1999-02-01 | Release date: | 1999-02-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site. Protein Sci., 8, 1999
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1B98
| NEUROTROPHIN 4 (HOMODIMER) | Descriptor: | CHLORIDE ION, PROTEIN (NEUROTROPHIN-4) | Authors: | Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S. | Deposit date: | 1999-02-22 | Release date: | 1999-02-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site. Protein Sci., 8, 1999
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1WWW
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1NT3
| HUMAN NEUROTROPHIN-3 | Descriptor: | PROTEIN (NEUROTROPHIN-3) | Authors: | Butte, M.J, Hwang, P.K, Mobley, W.C, Fletterick, R.J. | Deposit date: | 1999-05-17 | Release date: | 1999-06-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors. Biochemistry, 37, 1998
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1HCF
| Crystal structure of TrkB-d5 bound to neurotrophin-4/5 | Descriptor: | BDNF/NT-3 GROWTH FACTORS RECEPTOR, NEUROTROPHIN-4, SULFATE ION | Authors: | Banfield, M.J, Naylor, R.L, Robertson, A.G.S, Allen, S.J, Dawbarn, D, Brady, R.L. | Deposit date: | 2001-05-03 | Release date: | 2001-12-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Specificity in Trk-Receptor:Neurotrophin Interaction: The Crystal Structure of Trkb-D5 in Complex with Neurotrophin-4/5 Structure, 9, 2001
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1SG1
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2IFG
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3BUK
| Crystal Structure of the Neurotrophin-3 and p75NTR Symmetrical Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurotrophin-3, Tumor necrosis factor receptor superfamily member 16 | Authors: | Jiang, T, Gong, Y, Cao, P, Yu, H.J. | Deposit date: | 2008-01-02 | Release date: | 2008-07-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex. Nature, 454, 2008
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3IJ2
| Ligand-receptor structure | Descriptor: | Beta-nerve growth factor, Nerve growth factor receptor (TNFR superfamily, member 16) | Authors: | Feng, D, Garcia, K.C. | Deposit date: | 2009-08-03 | Release date: | 2010-01-12 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (3.75 Å) | Cite: | Molecular and structural insight into proNGF engagement of p75NTR and sortilin. J.Mol.Biol., 396, 2010
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4EAX
| Mouse NGF in complex with Lyso-PS | Descriptor: | Beta-nerve growth factor, O-[(S)-hydroxy{[(2S)-2-hydroxy-3-(octadec-9-enoyloxy)propyl]oxy}phosphoryl]-L-serine | Authors: | Jiang, T, Tong, Q. | Deposit date: | 2012-03-23 | Release date: | 2012-09-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and functional insights into lipid-bound nerve growth factors Faseb J., 26, 2012
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4EC7
| Cobra NGF in complex with lipid | Descriptor: | (2S)-1-hydroxy-3-(tetradecanoyloxy)propan-2-yl docosanoate, Venom nerve growth factor | Authors: | Jiang, T, Wang, F, Tong, Q. | Deposit date: | 2012-03-26 | Release date: | 2012-09-12 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and functional insights into lipid-bound nerve growth factors Faseb J., 26, 2012
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4EDX
| Nerve Growth Factor in Complex with Fab from mouse mAb 911 | Descriptor: | Beta-nerve growth factor, heavy chain of Fab of murine anti-NGF, light chain of FAB of murine anti-NGF | Authors: | Eigenbrot, C, Ultsch, M. | Deposit date: | 2012-03-27 | Release date: | 2014-04-02 | Last modified: | 2014-08-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes. MAbs, 6
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4EDW
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4EFV
| Crystal structure of OIF from Llama seminal plasma | Descriptor: | CHLORIDE ION, Ovulation-inducing factor (OIF), PHOSPHATE ION | Authors: | Van Straaten, K.E, Leduc, Y.A, Ratto, M.H, Valderrama, X.P, Delbaere, T.J, Pierson, R.A, Adams, G.P. | Deposit date: | 2012-03-30 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | The nerve of ovulation-inducing factor in semen. Proc.Natl.Acad.Sci.USA, 109, 2012
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4XPJ
| Crystal structure of Nerve growth factor in complex with lysophosphatidylinositol | Descriptor: | (2R)-2-hydroxy-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl tridecanoate, Beta-nerve growth factor | Authors: | Sun, H.L, Jiang, T. | Deposit date: | 2015-01-17 | Release date: | 2015-07-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.605 Å) | Cite: | The structure of nerve growth factor in complex with lysophosphatidylinositol Acta Crystallogr.,Sect.F, 71, 2015
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4ZBN
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5JZ7
| NGF IN COMPLEX WITH MEDI578 scFv | Descriptor: | Beta-nerve growth factor, MEDI578 scFv, heavy chain, ... | Authors: | Olsson, L.-L, Aagaard, A. | Deposit date: | 2016-05-16 | Release date: | 2017-01-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo. Sci Rep, 6, 2016
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5LSD
| recombinant mouse Nerve Growth Factor | Descriptor: | Beta-nerve growth factor | Authors: | Paoletti, F, de Chiara, C, Kelly, G, Lamba, D, Cattaneo, A, Pastore, A. | Deposit date: | 2016-08-25 | Release date: | 2017-07-05 | Last modified: | 2024-07-03 | Method: | SOLUTION NMR | Cite: | Conformational Rigidity within Plasticity Promotes Differential Target Recognition of Nerve Growth Factor. Front Mol Biosci, 3, 2016
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6FFY
| Structure of the mouse SorCS2-NGF complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-nerve growth factor, VPS10 domain-containing receptor SorCS2, ... | Authors: | Leloup, N.O.L, Janssen, B.J.C. | Deposit date: | 2018-01-09 | Release date: | 2018-08-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural insights into SorCS2-Nerve Growth Factor complex formation. Nat Commun, 9, 2018
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6XUO
| mature recombinant horse NGF | Descriptor: | Nerve growth factor, ZINC ION | Authors: | Kalnins, G. | Deposit date: | 2020-01-20 | Release date: | 2020-01-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | Mature horse nerve growth factor at 2.8 angstrom resolution To Be Published
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