4EAX

Mouse NGF in complex with Lyso-PS

Summary for 4EAX

Entry DOI	10.2210/pdb4eax/pdb
Descriptor	Beta-nerve growth factor, O-[(S)-hydroxy{[(2S)-2-hydroxy-3-(octadec-9-enoyloxy)propyl]oxy}phosphoryl]-L-serine (3 entities in total)
Functional Keywords	lyso-ps, phospholipid, hormone
Biological source	Mus musculus (mouse)
Cellular location	Secreted: P01139
Total number of polymer chains	4
Total formula weight	55012.21
Authors	Jiang, T.,Tong, Q. (deposition date: 2012-03-23, release date: 2012-09-12, Last modification date: 2023-11-08)
Primary citation	Tong, Q.,Wang, F.,Zhou, H.Z.,Sun, H.L.,Song, H.,Shu, Y.Y.,Gong, Y.,Zhang, W.T.,Cai, T.X.,Yang, F.Q.,Tang, J.,Jiang, T. Structural and functional insights into lipid-bound nerve growth factors Faseb J., 26:3811-3821, 2012 Cited by PubMed: 22649032 DOI: 10.1096/fj.12-207316 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation