1WWW
NGF IN COMPLEX WITH DOMAIN 5 OF THE TRKA RECEPTOR
Summary for 1WWW
Entry DOI | 10.2210/pdb1www/pdb |
Descriptor | PROTEIN (NERVE GROWTH FACTOR), PROTEIN (TRKA RECEPTOR) (3 entities in total) |
Functional Keywords | complex, trka receptor, nerve growth factor, cysteine knot, immunoglobulin like domain, nerve growth factor-trka complex complex, nerve growth factor/trka complex |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01138 Cell membrane; Single-pass type I membrane protein (By similarity): P04629 |
Total number of polymer chains | 4 |
Total formula weight | 49245.74 |
Authors | Wiesmann, C.,Ultsch, M.H.,De Vos, A.M. (deposition date: 1999-03-12, release date: 1999-09-15, Last modification date: 2023-08-23) |
Primary citation | Wiesmann, C.,Ultsch, M.H.,Bass, S.H.,de Vos, A.M. Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor. Nature, 401:184-188, 1999 Cited by PubMed: 10490030DOI: 10.1038/43705 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report