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1B8K
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1b8k
NEUROTROPHIN-3 FROM HUMAN
Descriptor:NEUROTROPHIN-3
Authors:Robinson, R.C., Radziejewski, C., Stuart, D.I., Jones, E.Y., Choe, S.
Deposit date:1999-02-01
Release date:1999-02-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
1B98
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1b98
NEUROTROPHIN 4 (HOMODIMER)
Descriptor:PROTEIN (NEUROTROPHIN-4)
Authors:Robinson, R.C., Radziejewski, C., Stuart, D.I., Jones, E.Y., Choe, S.
Deposit date:1999-02-22
Release date:1999-02-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
1BET
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1bet
NEW PROTEIN FOLD REVEALED BY A 2.3 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF NERVE GROWTH FACTOR
Descriptor:BETA-NERVE GROWTH FACTOR
Authors:Mcdonald, N.Q., Lapatto, R., Murray-Rust, J., Gunning, J., Wlodawer, A., Blundell, T.L.
Deposit date:1993-04-08
Release date:1994-05-31
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor.
Nature, 354, 1991
1BTG
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1btg
CRYSTAL STRUCTURE OF BETA NERVE GROWTH FACTOR AT 2.5 A RESOLUTION IN C2 SPACE GROUP WITH ZN IONS BOUND
Descriptor:BETA NERVE GROWTH FACTOR
Authors:Holland, D.R., Matthews, B.W.
Deposit date:1995-08-29
Release date:1996-03-08
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nerve growth factor in different crystal forms displays structural flexibility and reveals zinc binding sites.
J.Mol.Biol., 239, 1994
1NT3
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1nt3
HUMAN NEUROTROPHIN-3
Descriptor:NEUROTROPHIN-3
Authors:Butte, M.J., Hwang, P.K., Mobley, W.C., Fletterick, R.J.
Deposit date:1999-05-17
Release date:1999-06-06
Modification date:2011-11-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors.
Biochemistry, 37, 1998
4EAX
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4eax
MOUSE NGF IN COMPLEX WITH LYSO-PS
Descriptor:Beta-nerve growth factor
Authors:Jiang, T., Tong, Q.
Deposit date:2012-03-23
Release date:2012-09-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional insights into lipid-bound nerve growth factors
Faseb J., 26, 2012
4EC7
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4ec7
COBRA NGF IN COMPLEX WITH LIPID
Descriptor:Venom nerve growth factor
Authors:Jiang, T., Wang, F., Tong, Q.
Deposit date:2012-03-26
Release date:2012-09-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and functional insights into lipid-bound nerve growth factors
Faseb J., 26, 2012
4EDW
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4edw
NERVE GROWTH FACTOR IN COMPLEX WITH FAB FROM HUMANIZED VERSION OF MOUSE MAB 911 (TANEZUMAB)
Descriptor:Beta-nerve growth factor, tanezumab Fab light chain, tanezumab Fab heavy chain
Authors:Eigenbrot, C., Ultsch, M.
Deposit date:2012-03-27
Release date:2014-04-02
Modification date:2014-08-13
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
MAbs, 6
4EDX
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4edx
NERVE GROWTH FACTOR IN COMPLEX WITH FAB FROM MOUSE MAB 911
Descriptor:Beta-nerve growth factor, light chain of FAB of murine anti-NGF, heavy chain of Fab of murine anti-NGF
Authors:Eigenbrot, C., Ultsch, M.
Deposit date:2012-03-27
Release date:2014-04-02
Modification date:2014-08-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
MAbs, 6
4EFV
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4efv
CRYSTAL STRUCTURE OF OIF FROM LLAMA SEMINAL PLASMA
Descriptor:Ovulation-inducing factor (OIF)
Authors:Van Straaten, K.E., Leduc, Y.A., Ratto, M.H., Valderrama, X.P., Delbaere, T.J., Pierson, R.A., Adams, G.P.
Deposit date:2012-03-30
Release date:2012-08-22
Modification date:2012-09-26
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:The nerve of ovulation-inducing factor in semen.
Proc.Natl.Acad.Sci.USA, 109, 2012
1B8M
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1b8m
BRAIN DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN-4
Descriptor:BRAIN DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN-4
Authors:Robinson, R.C., Radziejewski, C., Stuart, D.I., Jones, E.Y., Choe, S.
Deposit date:1999-02-01
Release date:1999-02-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
1BND
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1bnd
STRUCTURE OF THE BRAIN-DERIVED NEUROTROPHIC FACTOR(SLASH)NEUROTROPHIN 3 HETERODIMER
Descriptor:BRAIN DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN 3
Authors:Robinson, R.C., Radziejewski, C., Stuart, D.I., Jones, E.Y.
Deposit date:1994-12-12
Release date:1996-04-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer.
Biochemistry, 34, 1995
1HCF
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1hcf
CRYSTAL STRUCTURE OF TRKB-D5 BOUND TO NEUROTROPHIN-4/5
Descriptor:NEUROTROPHIN-4, BDNF/NT-3 GROWTH FACTORS RECEPTOR
Authors:Banfield, M.J., Naylor, R.L., Robertson, A.G.S., Allen, S.J., Dawbarn, D., Brady, R.L.
Deposit date:2001-05-03
Release date:2001-12-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Specificity in Trk-Receptor:Neurotrophin Interaction: The Crystal Structure of Trkb-D5 in Complex with Neurotrophin-4/5
Structure, 9, 2001
1SG1
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1sg1
CRYSTAL STRUCTURE OF THE RECEPTOR-LIGAND COMPLEX BETWEEN NERVE GROWTH FACTOR AND THE COMMON NEUROTROPHIN RECEPTOR P75
Descriptor:Beta-nerve growth factor
Authors:He, X.L., Garcia, K.C.
Deposit date:2004-02-22
Release date:2004-06-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of nerve growth factor complexed with the shared neurotrophin receptor p75
Science, 304, 2004
1WWW
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1www
NGF IN COMPLEX WITH DOMAIN 5 OF THE TRKA RECEPTOR
Descriptor:NERVE GROWTH FACTOR/TRKA RECEPTOR COMOPLEX
Authors:Wiesmann, C., Ultsch, M.H., De Vos, A.M.
Deposit date:1999-03-12
Release date:1999-09-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor.
Nature, 401, 1999
3BUK
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3buk
CRYSTAL STRUCTURE OF THE NEUROTROPHIN-3 AND P75NTR SYMMETRICAL COMPLEX
Descriptor:Neurotrophin-3, Tumor necrosis factor receptor superfamily member 16
Authors:Jiang, T., Gong, Y., Cao, P., Yu, H.J.
Deposit date:2008-01-02
Release date:2008-07-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex.
Nature, 454, 2008
3IJ2
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3ij2
LIGAND-RECEPTOR STRUCTURE
Descriptor:Beta-nerve growth factor, Nerve growth factor receptor (TNFR superfamily, member 16)
Authors:Feng, D., Garcia, K.C.
Deposit date:2009-08-03
Release date:2010-01-12
Modification date:2010-03-23
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Molecular and structural insight into proNGF engagement of p75NTR and sortilin.
J.Mol.Biol., 396, 2010
1SGF
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1sgf
CRYSTAL STRUCTURE OF 7S NGF: A COMPLEX OF NERVE GROWTH FACTOR WITH FOUR BINDING PROTEINS (SERINE PROTEINASES)
Descriptor:NERVE GROWTH FACTOR
Authors:Bax, B.D.V., Blundell, T.L., Murray-Rust, J., Mcdonald, N.Q.
Deposit date:1997-08-08
Release date:1998-05-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins.
Structure, 5, 1997
2IFG
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2ifg
STRUCTURE OF THE EXTRACELLULAR SEGMENT OF HUMAN TRKA IN COMPLEX WITH NERVE GROWTH FACTOR
Descriptor:Structure of the extracellular segment of human TRKA in complex with nerve growth factor
Authors:He, X., Garcia, K.C.
Deposit date:2006-09-20
Release date:2007-02-13
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.
Neuron, 53, 2007
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entries available on 2014-11-26
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