PDB: 27 resultsInfo pagesStatus searchChemie searchBIRD

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7KTR	Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core) Descriptor: Ataxin-7, INOSITOL HEXAKISPHOSPHATE, Isoform 3 of Transcription factor SPT20 homolog, ... Authors: Herbst, D.A, Esbin, M.N, Nogales, E. Deposit date: 2020-11-24 Release date: 2021-11-10 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: Structure of the human SAGA coactivator complex. Nat.Struct.Mol.Biol., 28, 2021
7KTS	Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module) Descriptor: Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ... Authors: Herbst, D.A, Esbin, M.N, Nogales, E. Deposit date: 2020-11-24 Release date: 2021-11-10 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (19.09 Å) Cite: Structure of the human SAGA coactivator complex. Nat.Struct.Mol.Biol., 28, 2021
1DFN	CRYSTAL STRUCTURE OF DEFENSIN HNP-3, AN AMPHIPHILIC DIMER: MECHANISMS OF MEMBRANE PERMEABILIZATION Descriptor: DEFENSIN HNP-3 Authors: Hill, C.P, Yee, J, Selsted, M.E, Eisenberg, D. Deposit date: 1991-01-18 Release date: 1992-07-15 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization. Science, 251, 1991
8H7G	Cryo-EM structure of the human SAGA complex Descriptor: Ataxin-7, STAGA complex 65 subunit gamma, Splicing factor 3B subunit 3, ... Authors: Huang, J, Zhang, Y. Deposit date: 2022-10-20 Release date: 2022-12-14 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM structure of human SAGA transcriptional coactivator complex. Cell Discov, 8, 2022
4DU0	Crystal structure of human alpha-defensin 1, HNP1 (G17A mutant) Descriptor: CHLORIDE ION, GLYCEROL, Neutrophil defensin 1 Authors: Wu, X, Lu, W, Pazgier, M. Deposit date: 2012-02-21 Release date: 2012-04-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Invariant gly residue is important for alpha-defensin folding, dimerization, and function: a case study of the human neutrophil alpha-defensin HNP1 J.Biol.Chem., 287, 2012
2KHT	NMR Structure of human alpha defensin HNP-1 Descriptor: Neutrophil defensin 1 Authors: Zhang, Y, Li, S, Doherty, T.F, Lubkowski, J, Lu, W, Li, J, Barinka, C, Hong, M. Deposit date: 2009-04-11 Release date: 2010-02-09 Last modified: 2024-05-01 Method: SOLID-STATE NMR Cite: Resonance assignment and three-dimensional structure determination of a human alpha-defensin, HNP-1, by solid-state NMR. J.Mol.Biol., 397, 2010
3GNY	Crystal structure of human alpha-defensin 1 (HNP1) Descriptor: CHLORIDE ION, GLYCEROL, Neutrophil defensin 1 Authors: Pazgier, M, Lu, W.-Y. Deposit date: 2009-03-18 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Through the looking glass, mechanistic insights from enantiomeric human defensins. J.Biol.Chem., 284, 2009
2PM5	Human alpha-defensin 1 derivative (HNP1) Descriptor: Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1), PHOSPHATE ION Authors: Lubkowski, J, Pazgier, M, Lu, W. Deposit date: 2007-04-20 Release date: 2007-05-29 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Human alpha-defensin 1 derivative (HNP1) To be Published
2PM1	Derivative of human alpha-defensin 1 (HNP1) Descriptor: Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1) Authors: Lubkowski, J, Pazgier, M, Lu, W. Deposit date: 2007-04-20 Release date: 2007-05-29 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Derivative of human alpha-defensin 1 (HNP1) To be Published
2PM4	Human alpha-defensin 1 (multiple Arg->Lys mutant) Descriptor: Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1) Authors: Lubkowski, J, Pazgier, M, Lu, W. Deposit date: 2007-04-20 Release date: 2007-05-29 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs. J.Biol.Chem., 282, 2007
1GXY	crystal structure of the eucaryotic mono-ADP-ribosyltransferase ART2.2; CRYSTAL FORM A (P21) Descriptor: GLYCEROL, T-CELL ECTO-ADP-RIBOSYLTRANSFERASE 2 Authors: Mueller-Dieckmann, C, Schulz, G.E. Deposit date: 2002-04-15 Release date: 2002-09-26 Last modified: 2019-07-24 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Structure of the Ecto-Adp-Ribosyl Transferase Art2.2 From Rat J.Mol.Biol., 322, 2002
1GY0	crystal structure of the eucaryotic mono-ADP-ribosyltransferase ART2.2; CRYSTAL FORM C (P3121) Descriptor: T-CELL ECTO-ADP-RIBOSYLTRANSFERASE 2 Authors: Mueller-Dieckmann, C, Schulz, G.E. Deposit date: 2002-04-15 Release date: 2002-09-26 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Structure of the Ecto-Adp-Ribosyl Transferase Art2.2 From Rat J.Mol.Biol., 322, 2002
1GXZ	crystal structure of the eukaryotic mono-ADP-ribosyltransferase ART2.2; Crystal form B (P212121) Descriptor: 5-BROMONICOTINAMIDE, T-CELL ECTO-ADP-RIBOSYLTRANSFERASE 2 Authors: Mueller-Dieckmann, C, Schulz, G.E. Deposit date: 2002-04-15 Release date: 2002-09-26 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of the Ecto-Adp-Ribosyl Transferase Art2.2 From Rat J.Mol.Biol., 322, 2002
4LBF	Crystal structure of HUMAN ALPHA-DEFENSIN 1 (HNP1) I20A/L25A mutant Descriptor: GLYCEROL, Neutrophil defensin 1 Authors: Tolbert, W.D, Wu, X, Pazgier, M. Deposit date: 2013-06-20 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function. Plos One, 8, 2013
4LB1	Crystal structure of human alpha-defensin 1 (HNP1) Y16A/F28A mutant Descriptor: Neutrophil defensin 1 Authors: Tolbert, W.D, Wu, X, Pazgier, M. Deposit date: 2013-06-20 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function. Plos One, 8, 2013
4LBB	Crystal structure of human alpha-defensin 1 (HNP1) I20A mutant Descriptor: CHLORIDE ION, Neutrophil defensin 1 Authors: Tolbert, W.D, Wu, X, Pazgier, M. Deposit date: 2013-06-20 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.719 Å) Cite: Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function. Plos One, 8, 2013
4LB7	Crystal structure of human alpha-defensin 1 (HNP1) Y16A/I20A/L25A/F28A mutant. Descriptor: Neutrophil defensin 1 Authors: Tolbert, W.D, Wu, X, Pazgier, M. Deposit date: 2013-06-20 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.902 Å) Cite: Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function. Plos One, 8, 2013
3H6C	Crystal structure of human alpha-defensin 1 (Mutant Gln22Ala) Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Neutrophil defensin 1 Authors: Pazgier, M, Lu, W. Deposit date: 2009-04-23 Release date: 2010-03-09 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3HJ2	Crystal structure of covalent dimer of HNP1 Descriptor: HUMAN NEUTROPHIL PEPTIDE 1 Authors: Lubkowski, J, Pazgier, M, Lu, W. Deposit date: 2009-05-20 Release date: 2009-10-20 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: What Dictates the Multifaced Functions of the Human alpha-Defensin HNP1? To be Published
3HJD	X-ray structure of monomeric variant of HNP1 Descriptor: Human neutrophil peptide 1 Authors: Lubkowski, J, Pazgier, M, Lu, W. Deposit date: 2009-05-21 Release date: 2009-10-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.65 Å) Cite: What Dictates the Multifaced Functions of the Human alpha-Defensin HNP? To be Published
3LO2	Crystal structure of human alpha-defensin 1 (Y21A mutant) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Neutrophil defensin 1, SULFATE ION, ... Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3LO1	Crystal structure of human alpha-defensin 1 (Y16A mutant) Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, AZIDE ION, Neutrophil defensin 1 Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3LOE	Crystal structure of human alpha-defensin 1 (F28A mutant) Descriptor: GLYCEROL, Neutrophil defensin 1, SULFATE ION Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3LO4	Crystal structure of human alpha-defensin 1 (R24A mutant) Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Neutrophil defensin 1 Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3LO6	Crystal structure of human alpha-defensin 1 (W26Aba mutant) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Neutrophil defensin 1 Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010

 

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