2PM4
Human alpha-defensin 1 (multiple Arg->Lys mutant)
Summary for 2PM4
Entry DOI | 10.2210/pdb2pm4/pdb |
Related | 1DFN 1ZMH 1ZMI 1ZMK |
Descriptor | Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1) (2 entities in total) |
Functional Keywords | antimicrobial, defensin, mutant, antimicrobial protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P59665 |
Total number of polymer chains | 2 |
Total formula weight | 6824.16 |
Authors | Lubkowski, J.,Pazgier, M.,Lu, W. (deposition date: 2007-04-20, release date: 2007-05-29, Last modification date: 2023-08-30) |
Primary citation | Zou, G.,de Leeuw, E.,Li, C.,Pazgier, M.,Li, C.,Zeng, P.,Lu, W.Y.,Lubkowski, J.,Lu, W. Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs. J.Biol.Chem., 282:19653-19665, 2007 Cited by PubMed: 17452329DOI: 10.1074/jbc.M611003200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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