3H6C
Crystal structure of human alpha-defensin 1 (Mutant Gln22Ala)
Summary for 3H6C
Entry DOI | 10.2210/pdb3h6c/pdb |
Related | 3GNY 3GO0 |
Descriptor | Neutrophil defensin 1, DI(HYDROXYETHYL)ETHER, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | antimicrobial peptide, q22a mutant of human alpha defensin 1 q22a mutant of human neutrophil peptide 1, hnp1(q22a), antibiotic, antimicrobial, antiviral defense, defensin, disulfide bond, fungicide, phosphoprotein, secreted, antimicrobial protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P59665 |
Total number of polymer chains | 2 |
Total formula weight | 7108.72 |
Authors | Pazgier, M.,Lu, W. (deposition date: 2009-04-23, release date: 2010-03-09, Last modification date: 2021-10-27) |
Primary citation | Wei, G.,Pazgier, M.,de Leeuw, E.,Rajabi, M.,Li, J.,Zou, G.,Jung, G.,Yuan, W.,Lu, W.Y.,Lehrer, R.I.,Lu, W. Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285:16275-16285, 2010 Cited by PubMed: 20220136DOI: 10.1074/jbc.M110.102749 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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