3HJ2

Crystal structure of covalent dimer of HNP1

Summary for 3HJ2

• Entry DOI: 10.2210/pdb3hj2/pdb
• Related: 1zmn 1zmp 1zmq 2pm1 2pm4 2pm5 3HJD
• Descriptor: HUMAN NEUTROPHIL PEPTIDE 1 (2 entities in total)
• Functional Keywords: defensin, antimicrobial, chemotactic, cationic, cys-rich, covalent dimer, synthetic, antibiotic, antiviral defense, disulfide bond, fungicide, phosphoprotein, secreted, antimicrobial protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P59665
• Total number of polymer chains: 2
• Total formula weight: 7338.72

Authors

Lubkowski, J.,Pazgier, M.,Lu, W. (deposition date: 2009-05-20, release date: 2009-10-20, Last modification date: 2023-09-06)

• Primary citation: Wei, G.,de Leeuw, E.,Pazgier, M.,Rajabi, M.,Li, J.,Zou, G.,Ericksen, B.,Wu, Z.,Yuan, W.,Szmacinski, H.,Lu, W.-Y.,Lubkowski, J.,Lehrer, R.L.,Lu, W.; What Dictates the Multifaced Functions of the Human alpha-Defensin HNP1?; To be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)