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6QL7
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Structure of fatty acid synthase complex with bound gamma subunit from Saccharomyces cerevisiae at 4.6 angstrom
分子名称: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Translation machinery-associated protein 17
著者Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
登録日2019-01-31
公開日2020-03-18
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
8EYK
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Atomic model of the core modifying region of human fatty acid synthase in complex with TVB-2640
分子名称: Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, denifanstat
著者Hasan, S.M.N, Keszei, A, Mazhab-Jafari, M.T.
登録日2022-10-27
公開日2023-05-24
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.
Nat Commun, 14, 2023
8EYI
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BU of 8eyi by Molmil
Atomic model of the core modifying region of human fatty acid synthase
分子名称: Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hasan, S.M.N, Keszei, A, Mazhab-Jafari, M.T.
登録日2022-10-27
公開日2023-05-24
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.
Nat Commun, 14, 2023
8GKC
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BU of 8gkc by Molmil
Atomic model of the core modifying region of human fatty acid synthase in complex with TVB-2640 - C2 refinement
分子名称: Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, denifanstat
著者Hasan, S.M.N, Keszei, A, Mazhab-Jafari, M.T.
登録日2023-03-17
公開日2023-05-24
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.
Nat Commun, 14, 2023
2VZ8
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Crystal Structure of Mammalian Fatty Acid Synthase
分子名称: FATTY ACID SYNTHASE
著者Maier, T, Leibundgut, M, Ban, N.
登録日2008-07-31
公開日2008-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.219 Å)
主引用文献The Crystal Structure of a Mammalian Fatty Acid Synthase.
Science, 321, 2008
4V59
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BU of 4v59 by Molmil
Crystal structure of fatty acid synthase complexed with nadp+ from thermomyces lanuginosus at 3.1 angstrom resolution.
分子名称: FATTY ACID SYNTHASE ALPHA SUBUNITS, FATTY ACID SYNTHASE BETA SUBUNITS, FLAVIN MONONUCLEOTIDE, ...
著者Jenni, S, Leibundgut, M, Boehringer, D, Frick, C, Mikolasek, B, Ban, N.
登録日2007-03-09
公開日2014-07-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling
Science, 316, 2007
4V58
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Crystal structure of fatty acid synthase from thermomyces lanuginosus at 3.1 angstrom resolution.
分子名称: FATTY ACID SYNTHASE ALPHA SUBUNITS, FATTY ACID SYNTHASE BETA SUBUNITS, FLAVIN MONONUCLEOTIDE
著者Jenni, S, Leibundgut, M, Boehringer, D, Frick, C, Mikolasek, B, Ban, N.
登録日2007-03-09
公開日2014-07-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling
Science, 316, 2007
4V8L
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Cryo-EM Structure of the Mycobacterial Fatty Acid Synthase
分子名称: FATTY ACID SYNTHASE, FLAVIN MONONUCLEOTIDE
著者Boehringer, D, Ban, N, Leibundgut, M.
登録日2012-12-06
公開日2014-07-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献7.5-A Cryo-Em Structure of the Mycobacterial Fatty Acid Synthase.
J.Mol.Biol., 425, 2013
6WC7
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Acyl carrier protein (ACP) domain bound to dehydratase (DH) domain in fungal fatty acid synthase (FAS)
分子名称: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
著者Lou, J.W, Mazhab-Jafari, M.T.
登録日2020-03-29
公開日2020-06-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Steric occlusion regulates proximal interactions of acyl carrier protein domain in fungal fatty acid synthase.
Commun Biol, 3, 2020
6TA1
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Fatty acid synthase of S. cerevisiae
分子名称: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ...
著者Vonck, J, D'Imprima, E, Joppe, M, Grininger, M.
登録日2019-10-29
公開日2019-11-06
最終更新日2020-05-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The resolution revolution in cryoEM requires high-quality sample preparation: a rapid pipeline to a high-resolution map of yeast fatty acid synthase.
Iucrj, 7, 2020
7BC5
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BU of 7bc5 by Molmil
Cryo-EM structure of ACP domain from Pichia pastoris fatty acid synthase (FAS)
分子名称: Fatty acid synthase subunit alpha
著者Snowden, J.S, Alzahrani, J, Sherry, L, Stacey, M, Rowlands, D.J, Ranson, N.A, Stonehouse, N.J.
登録日2020-12-18
公開日2021-05-19
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insight into Pichia pastoris fatty acid synthase.
Sci Rep, 11, 2021
6QL5
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Structure of fatty acid synthase complex with bound gamma subunit from Saccharomyces cerevisiae at 2.8 angstrom
分子名称: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
著者Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
登録日2019-01-31
公開日2020-03-18
最終更新日2020-04-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL6
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Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom
分子名称: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ...
著者Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
登録日2019-01-31
公開日2020-03-18
最終更新日2020-04-08
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL9
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Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom
分子名称: 1,2-ETHANEDIOL, 4'-PHOSPHOPANTETHEINE, ACETATE ION, ...
著者Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
登録日2019-01-31
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
2VKZ
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Structure of the cerulenin-inhibited fungal fatty acid synthase type I multienzyme complex
分子名称: (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, FATTY ACID SYNTHASE SUBUNIT ALPHA, ...
著者Johansson, P, Wiltschi, B, Kumari, P, Kessler, B, Vonrhein, C, Vonck, J, Oesterhelt, D, Grininger, M.
登録日2008-01-07
公開日2008-08-12
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Inhibition of the Fungal Fatty Acid Synthase Type I Multienzyme Complex.
Proc.Natl.Acad.Sci.USA, 105, 2008
2UV8
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BU of 2uv8 by Molmil
Crystal structure of yeast fatty acid synthase with stalled acyl carrier protein at 3.1 angstrom resolution
分子名称: FATTY ACID SYNTHASE SUBUNIT ALPHA (FAS2), FATTY ACID SYNTHASE SUBUNIT BETA (FAS1), FLAVIN MONONUCLEOTIDE
著者Leibundgut, M, Jenni, S, Frick, C, Ban, N.
登録日2007-03-09
公開日2007-04-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis for Substrate Delivery by Acyl Carrier Protein in the Yeast Fatty Acid Synthase
Science, 316, 2007
2CF2
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Architecture of mammalian fatty acid synthase
分子名称: FATTY ACID SYNTHASE, DH DOMAIN, ER DOMAIN, ...
著者Maier, T, Jenni, S, Ban, N.
登録日2006-02-14
公開日2006-03-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Architecture of Mammalian Fatty Acid Synthase at 4.5 A Resolution.
Science, 311, 2006
1XKT
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BU of 1xkt by Molmil
Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain
分子名称: fatty acid synthase
著者Chakravarty, B, Gu, Z, Chirala, S.S, Wakil, S.J, Quiocho, F.A.
登録日2004-09-29
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain.
Proc.Natl.Acad.Sci.Usa, 101, 2004
2VZ9
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BU of 2vz9 by Molmil
Crystal Structure of Mammalian Fatty Acid Synthase in complex with NADP
分子名称: FATTY ACID SYNTHASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Maier, T, Leibundgut, M, Ban, N.
登録日2008-07-31
公開日2008-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The Crystal Structure of a Mammalian Fatty Acid Synthase.
Science, 321, 2008
2PFF
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BU of 2pff by Molmil
Structural Insights of Yeast Fatty Acid Synthase
分子名称: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Tail protein
著者Xiong, Y, Lomakin, I.B, Steitz, T.A.
登録日2007-04-04
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural Insights of Yeast Fatty Acid Synthase
Cell(Cambridge,Mass.), 129, 2007
2PNG
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BU of 2png by Molmil
Type I rat fatty acid synthase acyl carrier protein (ACP) domain
分子名称: Fatty acid synthase (EC 2.3.1.85)
著者Ploskon, E.A, Arthur, C.J, Evans, S.E, Williams, C, Crosby, J, Crump, M.P.
登録日2007-04-24
公開日2007-06-05
最終更新日2022-08-24
実験手法SOLUTION NMR
主引用文献A Mammalian type I Fatty Acid synthase acyl carrier protein domain does not sequester acyl chains.
J.Biol.Chem., 283, 2008
4V8W
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BU of 4v8w by Molmil
Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex
分子名称: FLAVIN MONONUCLEOTIDE, TYPE-I FATTY ACID SYNTHASE
著者Ciccarelli, L, Connell, S.R, Enderle, M, Mills, D.J, Vonck, J, Grininger, M.
登録日2013-04-18
公開日2014-07-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (17.5 Å)
主引用文献Structure and Conformational Variability of the Mycobacterium Tuberculosis Fatty Acid Synthase Multienzyme Complex.
Structure, 21, 2013
4V8V
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Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex
分子名称: FLAVIN MONONUCLEOTIDE, TYPE-I FATTY ACID SYNTHASE
著者Ciccarelli, L, Connell, S.R, Enderle, M, Mills, D.J, Vonck, J, Grininger, M.
登録日2013-04-18
公開日2014-07-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Structure and Conformational Variability of the Mycobacterium Tuberculosis Fatty Acid Synthase Multienzyme Complex.
Structure, 21, 2013
4W82
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Enoyl-acyl carrier protein-reductase domain from human fatty acid synthase
分子名称: CHLORIDE ION, Fatty acid synthase, MAGNESIUM ION, ...
著者Sippel, K.H, Vyas, N.K, Sankaran, B, Quiocho, F.A.
登録日2014-08-22
公開日2014-10-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the human Fatty Acid synthase enoyl-acyl carrier protein-reductase domain complexed with triclosan reveals allosteric protein-protein interface inhibition.
J.Biol.Chem., 289, 2014
7BC4
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BU of 7bc4 by Molmil
Cryo-EM structure of fatty acid synthase (FAS) from Pichia pastoris
分子名称: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
著者Snowden, J.S, Alzahrani, J, Sherry, L, Stacey, M, Rowlands, D.J, Ranson, N.A, Stonehouse, N.J.
登録日2020-12-18
公開日2021-05-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insight into Pichia pastoris fatty acid synthase.
Sci Rep, 11, 2021

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