1XKT
Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain
Summary for 1XKT
Entry DOI | 10.2210/pdb1xkt/pdb |
Descriptor | fatty acid synthase (2 entities in total) |
Functional Keywords | human fatty acid synthase, thioesterase, specificity, drug target, hydroxylase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P49327 |
Total number of polymer chains | 2 |
Total formula weight | 63564.08 |
Authors | Chakravarty, B.,Gu, Z.,Chirala, S.S.,Wakil, S.J.,Quiocho, F.A. (deposition date: 2004-09-29, release date: 2004-10-26, Last modification date: 2024-02-14) |
Primary citation | Chakravarty, B.,Gu, Z.,Chirala, S.S.,Wakil, S.J.,Quiocho, F.A. Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain. Proc.Natl.Acad.Sci.Usa, 101:15567-15572, 2004 Cited by PubMed: 15507492DOI: 10.1073/pnas.0406901101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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