1XKT
Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: For thioesterase activity => ECO:0000255|PROSITE-ProRule:PRU10022, ECO:0000269|PubMed:17618296 |
| Chain | Residue | Details |
| A | SER2308 | |
| B | SER2308 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: For thioesterase activity => ECO:0000255|PROSITE-ProRule:PRU10022 |
| Chain | Residue | Details |
| A | HIS2481 | |
| B | HIS2481 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648 |
| Chain | Residue | Details |
| A | SER2236 | |
| B | SER2236 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P19096 |
| Chain | Residue | Details |
| A | LYS2391 | |
| B | LYS2391 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25114211 |
| Chain | Residue | Details |
| A | LYS2449 | |
| B | LYS2449 |
