7ONI
| Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2* | Descriptor: | Cullin-5, E3 ubiquitin-protein ligase ARIH2, NEDD8, ... | Authors: | Kostrhon, S.P, prabu, J.R, Schulman, B.A. | Deposit date: | 2021-05-25 | Release date: | 2021-09-15 | Last modified: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation. Nat.Chem.Biol., 17, 2021
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7OD1
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5XEW
| Crystal structure of the [Ni2+-(chromomycin A3)2]-CCG repeats complex | Descriptor: | (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ... | Authors: | Tseng, W.H, Wu, P.C, Hou, M.H. | Deposit date: | 2017-04-06 | Release date: | 2017-06-21 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Induced-Fit Recognition of CCG Trinucleotide Repeats by a Nickel-Chromomycin Complex Resulting in Large-Scale DNA Deformation Angew. Chem. Int. Ed. Engl., 56, 2017
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5YZE
| Crystal structure of the [Co2+-(chromomycin A3)2]-d(CCG)3 complex | Descriptor: | (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ... | Authors: | Hou, M.H, Chen, Y.W, Wu, P.C, Satange, R.B. | Deposit date: | 2017-12-14 | Release date: | 2018-10-17 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | CoII(Chromomycin)2 Complex Induces a Conformational Change of CCG Repeats from i-Motif to Base-Extruded DNA Duplex Int J Mol Sci, 19, 2018
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4X1H
| Opsin/G(alpha) peptide complex stabilized by nonyl-glucoside | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-terminal derived peptide of guanine nucleotide-binding protein G(t) subunit alpha-1, PALMITIC ACID, ... | Authors: | Blankenship, E, Lodowski, D.T. | Deposit date: | 2014-11-24 | Release date: | 2015-11-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | The High-Resolution Structure of Activated Opsin Reveals a Conserved Solvent Network in the Transmembrane Region Essential for Activation. Structure, 23, 2015
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5AC2
| human aldehyde dehydrogenase 1A1 with duocarmycin analog | Descriptor: | 1-[(1S)-1-methyl-5-oxidanyl-1,2-dihydrobenzo[e]indol-3-yl]hexan-1-one, RETINAL DEHYDROGENASE 1, YTTERBIUM (III) ION, ... | Authors: | Koch, M.F, Harteis, S, Blank, I.D, Pestel, G, Tietze, L.F, Ochsenfeld, C, Schneider, S, Sieber, S.A. | Deposit date: | 2015-08-11 | Release date: | 2015-08-26 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues. Angew.Chem.Int.Ed.Engl., 54, 2015
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6J0I
| Structure of [Co2+-(Chromomycin A3)2]-d(TTGGCGAA)2 complex | Descriptor: | 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYROXY-7-METHYLANTHRACENE, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ... | Authors: | Satange, R.B, Chuang, C.Y, Hou, M.H. | Deposit date: | 2018-12-24 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation. Nucleic Acids Res., 47, 2019
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6L76
| Crystal structure of the Ni(II)(Chro)2-d(TTGGGCCGAA/TTCGGCCCAA) complex at 2.94 angstrom resolution | Descriptor: | (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ... | Authors: | Hou, M.H, Jhan, C.R, Satange, R.B, Lin, S.M. | Deposit date: | 2019-10-31 | Release date: | 2021-01-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction. Nucleic Acids Res., 49, 2021
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6N6W
| OXA-23 mutant F110A/M221A neutral pH form | Descriptor: | Beta-lactamase oxa23 | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2018-11-27 | Release date: | 2018-12-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases. Antimicrob. Agents Chemother., 63, 2019
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6N6V
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6N6T
| OXA-23 mutant F110A/M221A low pH form | Descriptor: | Beta-lactamase oxa23, CITRATE ANION | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2018-11-27 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases. Antimicrob. Agents Chemother., 63, 2019
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6N6Y
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8W12
| Cryo-EM structure of VP3-VP6 heterohexamer | Descriptor: | Core protein VP3, VP6 | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | Deposit date: | 2024-02-14 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 2024
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8W19
| Cryo-EM structure of BTV star-subcore | Descriptor: | Core protein VP3, VP6 | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | Deposit date: | 2024-02-15 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 2024
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8W1C
| Cryo-EM structure of BTV pre-subcore | Descriptor: | Core protein VP3, VP6 | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | Deposit date: | 2024-02-15 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 2024
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8W1I
| Cryo-EM structure of BTV subcore | Descriptor: | Core protein VP3 | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | Deposit date: | 2024-02-16 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 2024
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8W1O
| Cryo-EM structure of BTV virion | Descriptor: | Core protein VP3, Outer capsid protein VP2, RNA-1, ... | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | Deposit date: | 2024-02-16 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 2024
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8W1R
| Cryo-EM structure of BTV core | Descriptor: | Core protein VP3, RNA-directed RNA polymerase | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | Deposit date: | 2024-02-17 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 2024
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8W1S
| Cryo-EM structure of BTV pre-core | Descriptor: | Core protein VP3, RNA-directed RNA polymerase | Authors: | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | Deposit date: | 2024-02-17 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 2024
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3PTL
| Crystal structure of proteinase K inhibited by a lactoferrin nonapeptide, Lys-Gly-Glu-Ala-Asp-Ala-Leu-Ser-Leu-Asp at 1.3 A resolution. | Descriptor: | 10-mer peptide from Lactoferrin, Proteinase K | Authors: | Shukla, P.K, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2010-12-03 | Release date: | 2010-12-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal structure of proteinase K inhibited by a lactoferrin nonapeptide, Lys-Gly-Glu-Ala-Asp-Ala-Leu-Ser-Leu-Asp at 1.3 A resolution. TO BE PUBLISHED
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7YOB
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4JF5
| Structure of OXA-23 at pH 4.1 | Descriptor: | 1,2-ETHANEDIOL, Beta-lactamase, CITRATE ANION | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2013-02-27 | Release date: | 2013-09-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structural Basis for Carbapenemase Activity of the OXA-23 beta-Lactamase from Acinetobacter baumannii. Chem.Biol., 20, 2013
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4JF4
| OXA-23 meropenem complex | Descriptor: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase | Authors: | Smith, C.A, Vakulenko, S.B, Toth, M. | Deposit date: | 2013-02-27 | Release date: | 2013-09-25 | Last modified: | 2013-10-09 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural Basis for Carbapenemase Activity of the OXA-23 beta-Lactamase from Acinetobacter baumannii. Chem.Biol., 20, 2013
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4JF6
| Structure of OXA-23 at pH 7.0 | Descriptor: | Beta-lactamase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2013-02-27 | Release date: | 2013-09-25 | Last modified: | 2013-10-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Carbapenemase Activity of the OXA-23 beta-Lactamase from Acinetobacter baumannii. Chem.Biol., 20, 2013
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4K0X
| X-ray Crystal Structure of OXA-23 from Acinetobacter baumannii | Descriptor: | BICARBONATE ION, Beta-lactamase | Authors: | Klinger, N.V, Ramey, M.E, Leonard, D.A, Powers, R.A. | Deposit date: | 2013-04-04 | Release date: | 2013-08-07 | Last modified: | 2013-10-23 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam. Antimicrob.Agents Chemother., 57, 2013
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