Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4ZRK
DownloadVisualize
BU of 4zrk by Molmil
Merlin-FERM and Lats1 complex
分子名称: Merlin, Serine/threonine-protein kinase LATS1
著者Lin, Z, Li, Y, Wei, Z, Zhang, M.
登録日2015-05-12
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.316 Å)
主引用文献Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
6QLZ
DownloadVisualize
BU of 6qlz by Molmil
IDOL F3ab subdomain
分子名称: E3 ubiquitin-protein ligase MYLIP
著者Martinelli, L, Johansson, P, Wan, P.T, Gunnarsson, J, Guo, H, Boyd, H.
登録日2019-02-01
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.343 Å)
主引用文献Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site.
J.Biol.Chem., 295, 2020
8CIU
DownloadVisualize
BU of 8ciu by Molmil
The FERM domain of human moesin mutant H288A
分子名称: Moesin
著者Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E.
登録日2023-02-10
公開日2023-03-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J.Biol.Chem., 299, 2023
3X23
DownloadVisualize
BU of 3x23 by Molmil
Radixin complex
分子名称: Peptide from Matrix metalloproteinase-14, Radixin
著者Terawaki, S, Kitano, K, Aoyama, M, Mori, T, Hakoshima, T.
登録日2014-12-09
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.396 Å)
主引用文献MT1-MMP recognition by ERM proteins and its implication in CD44 shedding
Genes Cells, 20, 2015
1J19
DownloadVisualize
BU of 1j19 by Molmil
Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide
分子名称: 16-mer peptide from Intercellular adhesion molecule-2, radixin
著者Hamada, K, Shimizu, T, Yonemura, S, Tsukita, S, Tsukita, S, Hakoshima, T.
登録日2002-12-02
公開日2003-03-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex
EMBO J., 22, 2003
2D10
DownloadVisualize
BU of 2d10 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-1 C-terminal tail peptide
分子名称: Ezrin-radixin-moesin binding phosphoprotein 50, Radixin
著者Terawaki, S, Maesaki, R, Hakoshima, T.
登録日2005-08-11
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
6QLY
DownloadVisualize
BU of 6qly by Molmil
IDOL FERM domain
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase MYLIP, SULFATE ION
著者Martinelli, L, Sixma, T.K.
登録日2019-02-01
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site.
J.Biol.Chem., 295, 2020
7EDR
DownloadVisualize
BU of 7edr by Molmil
The crystal structure of the FERM and C-terminal domain complex of Drosophila Merlin
分子名称: Moesin/ezrin/radixin homolog 2
著者Zhang, F, Long, J, Zhou, H.
登録日2021-03-16
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.527 Å)
主引用文献The crystal structure of the FERM and C-terminal domain complex of Drosophila Merlin.
Biochem.Biophys.Res.Commun., 553, 2021
8CIT
DownloadVisualize
BU of 8cit by Molmil
The FERM domain of human moesin mutant L281R
分子名称: Moesin
著者Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E.
登録日2023-02-10
公開日2023-03-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.536 Å)
主引用文献Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J.Biol.Chem., 299, 2023
4P7I
DownloadVisualize
BU of 4p7i by Molmil
Crystal structure of the Merlin FERM/DCAF1 complex
分子名称: GLYCEROL, Merlin, Protein VPRBP
著者Wei, Z, Li, Y, Zhang, M.
登録日2014-03-27
公開日2014-04-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1.
J.Biol.Chem., 289, 2014
6CDS
DownloadVisualize
BU of 6cds by Molmil
Human neurofibromin 2/merlin/schwannomin residues 1-339 in complex with PIP2
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Merlin, ...
著者Chinthalapudi, K, Sharff, A.J, Bricogne, G, Izard, T.
登録日2018-02-09
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.
Nat Commun, 9, 2018
3U8Z
DownloadVisualize
BU of 3u8z by Molmil
human merlin FERM domain
分子名称: Merlin
著者Yogesha, S.D, Sharff, A.J, Giovannini, M, Bricogne, G, Izard, T.
登録日2011-10-17
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor.
Protein Sci., 20, 2011
1E5W
DownloadVisualize
BU of 1e5w by Molmil
Structure of isolated FERM domain and first long helix of moesin
分子名称: MOESIN
著者Edwards, S.D, Keep, N.H.
登録日2000-08-03
公開日2001-06-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The 2.7 A Crystal Structure of the Activated Ferm Domain of Moesin: An Analysis of Structural Changes on Activation
Biochemistry, 40, 2001
4ZRI
DownloadVisualize
BU of 4zri by Molmil
Crystal structure of Merlin-FERM and Lats2
分子名称: Merlin, Serine/threonine-protein kinase LATS2
著者Li, F, Zhou, H, Long, J, Shen, Y.
登録日2015-05-12
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
1GG3
DownloadVisualize
BU of 1gg3 by Molmil
CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN
分子名称: ERYTHROID MEMBRANE PROTEIN 4.1R
著者Han, B.G.
登録日2000-07-11
公開日2001-01-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Nat.Struct.Biol., 7, 2000
1GC7
DownloadVisualize
BU of 1gc7 by Molmil
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN
分子名称: RADIXIN
著者Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
登録日2000-07-21
公開日2000-09-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
2D2Q
DownloadVisualize
BU of 2d2q by Molmil
Crystal structure of the dimerized radixin FERM domain
分子名称: Radixin
著者Kitano, K, Yusa, F, Hakoshima, T.
登録日2005-09-15
公開日2006-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2EMT
DownloadVisualize
BU of 2emt by Molmil
Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule PSGL-1
分子名称: P-selectin glycoprotein ligand 1, Radixin
著者Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T.
登録日2007-03-28
公開日2008-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of PSGL-1 binding to ERM proteins
Genes Cells, 12, 2007
2D11
DownloadVisualize
BU of 2d11 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide
分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF2, Radixin
著者Terawaki, S, Maesaki, R, Hakoshima, T.
登録日2005-08-11
公開日2006-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
1GC6
DownloadVisualize
BU of 1gc6 by Molmil
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE
分子名称: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN
著者Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
登録日2000-07-21
公開日2000-09-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
2EMS
DownloadVisualize
BU of 2ems by Molmil
Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule CD43
分子名称: Leukosialin, Radixin
著者Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T.
登録日2007-03-28
公開日2008-04-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins
J.Mol.Biol., 381, 2008
1ISN
DownloadVisualize
BU of 1isn by Molmil
Crystal structure of merlin FERM domain
分子名称: merlin
著者Shimizu, T, Seto, A, Maita, N, Hamada, K, Tsukita, S, Tsukita, S, Hakoshima, T.
登録日2001-12-13
公開日2002-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
J.Biol.Chem., 277, 2002
6D2Q
DownloadVisualize
BU of 6d2q by Molmil
Crystal structure of the FERM domain of zebrafish FARP1
分子名称: FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
著者Kuo, Y.C, Zhang, X.
登録日2018-04-13
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
2I1K
DownloadVisualize
BU of 2i1k by Molmil
Moesin from Spodoptera frugiperda reveals the coiled-coil domain at 3.0 angstrom resolution
分子名称: CHLORIDE ION, GLYCEROL, Moesin, ...
著者Nance, M.R, Tesmer, J.J.G.
登録日2006-08-14
公開日2006-12-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
8GXE
DownloadVisualize
BU of 8gxe by Molmil
PTPN21 FERM PTP complex
分子名称: CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 21
著者Chen, L, Zheng, Y.Y, Zhou, C.
登録日2022-09-19
公開日2023-09-27
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024

219869

件を2024-05-15に公開中

PDB statisticsPDBj update infoContact PDBjnumon