6QLZ

IDOL F3ab subdomain

Summary for 6QLZ

• Entry DOI: 10.2210/pdb6qlz/pdb
• Related: 6QLY
• Descriptor: E3 ubiquitin-protein ligase MYLIP (2 entities in total)
• Functional Keywords: e3 ligase cholesterol metabolism ldlr degradation, ligase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 33388.83

Authors

Martinelli, L.,Johansson, P.,Wan, P.T.,Gunnarsson, J.,Guo, H.,Boyd, H. (deposition date: 2019-02-01, release date: 2020-02-19, Last modification date: 2024-01-24)

• Primary citation: Martinelli, L.,Adamopoulos, A.,Johansson, P.,Wan, P.T.,Gunnarsson, J.,Guo, H.,Boyd, H.,Zelcer, N.,Sixma, T.K.; Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site.; J.Biol.Chem., 295:13570-13583, 2020; PubMed: 32727844; DOI: 10.1074/jbc.RA120.014349

Experimental method

X-RAY DIFFRACTION (2.343 Å)