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3BIN
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BU of 3bin by Molmil
Structure of the DAL-1 and TSLC1 (372-383) complex
分子名称: Band 4.1-like protein 3, Cell adhesion molecule 1
著者Busam, R.D, Arrowsmith, C.H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Berglund, H, Persson, C, Hallberg, B.M.
登録日2007-11-30
公開日2008-01-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B)
J.Biol.Chem., 286, 2011
6CDS
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BU of 6cds by Molmil
Human neurofibromin 2/merlin/schwannomin residues 1-339 in complex with PIP2
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Merlin, ...
著者Chinthalapudi, K, Sharff, A.J, Bricogne, G, Izard, T.
登録日2018-02-09
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.
Nat Commun, 9, 2018
6D2Q
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BU of 6d2q by Molmil
Crystal structure of the FERM domain of zebrafish FARP1
分子名称: FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
著者Kuo, Y.C, Zhang, X.
登録日2018-04-13
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
6D21
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BU of 6d21 by Molmil
Crystal structure of the FERM domain of zebrafish FARP2
分子名称: FERM, RhoGEF and pleckstrin domain protein 2
著者Kuo, Y.C, Zhang, X.
登録日2018-04-12
公開日2018-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
6D2K
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BU of 6d2k by Molmil
Crystal structure of the FERM domain of mouse FARP2
分子名称: FERM, ARHGEF and pleckstrin domain-containing protein 2
著者He, X, Zhang, X.
登録日2018-04-13
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
4P7I
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BU of 4p7i by Molmil
Crystal structure of the Merlin FERM/DCAF1 complex
分子名称: GLYCEROL, Merlin, Protein VPRBP
著者Wei, Z, Li, Y, Zhang, M.
登録日2014-03-27
公開日2014-04-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1.
J.Biol.Chem., 289, 2014
8CIT
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BU of 8cit by Molmil
The FERM domain of human moesin mutant L281R
分子名称: Moesin
著者Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E.
登録日2023-02-10
公開日2023-03-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.536 Å)
主引用文献Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J.Biol.Chem., 299, 2023
8CIU
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BU of 8ciu by Molmil
The FERM domain of human moesin mutant H288A
分子名称: Moesin
著者Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E.
登録日2023-02-10
公開日2023-03-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J.Biol.Chem., 299, 2023
8CIR
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BU of 8cir by Molmil
The FERM domain of human moesin with a bound peptide identified by phage display
分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, ...
著者Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E.
登録日2023-02-10
公開日2023-03-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J.Biol.Chem., 299, 2023
8CIS
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BU of 8cis by Molmil
The FERM domain of human moesin with two bound peptides identified by phage display
分子名称: 1,2-ETHANEDIOL, ACETATE ION, C3P, ...
著者Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E.
登録日2023-02-10
公開日2023-03-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J.Biol.Chem., 299, 2023
4RMA
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BU of 4rma by Molmil
Crystal structure of the FERM domain of human ezrin
分子名称: Ezrin, SULFATE ION
著者Phang, J.M, Harrop, S.J, Duff, A.P, Wilk, K.E, Curmi, P.M.G.
登録日2014-10-21
公開日2015-12-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin.
Biochem. J., 473, 2016
4RM8
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BU of 4rm8 by Molmil
Crystal structure of human ezrin in space group P21
分子名称: Ezrin
著者Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G.
登録日2014-10-20
公開日2015-12-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin.
Biochem. J., 473, 2016
4RM9
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BU of 4rm9 by Molmil
Crystal structure of human ezrin in space group C2221
分子名称: Ezrin
著者Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G.
登録日2014-10-21
公開日2015-12-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin.
Biochem. J., 473, 2016
2D10
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BU of 2d10 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-1 C-terminal tail peptide
分子名称: Ezrin-radixin-moesin binding phosphoprotein 50, Radixin
著者Terawaki, S, Maesaki, R, Hakoshima, T.
登録日2005-08-11
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D11
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BU of 2d11 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide
分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF2, Radixin
著者Terawaki, S, Maesaki, R, Hakoshima, T.
登録日2005-08-11
公開日2006-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D2Q
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BU of 2d2q by Molmil
Crystal structure of the dimerized radixin FERM domain
分子名称: Radixin
著者Kitano, K, Yusa, F, Hakoshima, T.
登録日2005-09-15
公開日2006-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2EMS
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BU of 2ems by Molmil
Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule CD43
分子名称: Leukosialin, Radixin
著者Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T.
登録日2007-03-28
公開日2008-04-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins
J.Mol.Biol., 381, 2008
2EMT
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BU of 2emt by Molmil
Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule PSGL-1
分子名称: P-selectin glycoprotein ligand 1, Radixin
著者Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T.
登録日2007-03-28
公開日2008-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of PSGL-1 binding to ERM proteins
Genes Cells, 12, 2007
2HE7
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BU of 2he7 by Molmil
FERM domain of EPB41L3 (DAL-1)
分子名称: Band 4.1-like protein 3
著者Hallberg, B.M, Busam, R.D, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Schiavone, L.H, Johansson, I, Hogbom, M, Karlberg, T, Kotenyova, T, Nilvebrandt, J, Norberg, P, Stenmark, P, Nordlund, P, Nilsson-ehle, P, Nyman, T, Ogg, D, Sagemark, J, Sundstrom, M, Uppenberg, J, Van den berg, S, Weigelt, J, Persson, C, Thorsell, A.G, Structural Genomics Consortium (SGC)
登録日2006-06-21
公開日2006-07-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B).
J.Biol.Chem., 286, 2011
1E5W
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BU of 1e5w by Molmil
Structure of isolated FERM domain and first long helix of moesin
分子名称: MOESIN
著者Edwards, S.D, Keep, N.H.
登録日2000-08-03
公開日2001-06-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The 2.7 A Crystal Structure of the Activated Ferm Domain of Moesin: An Analysis of Structural Changes on Activation
Biochemistry, 40, 2001
1GG3
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BU of 1gg3 by Molmil
CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN
分子名称: ERYTHROID MEMBRANE PROTEIN 4.1R
著者Han, B.G.
登録日2000-07-11
公開日2001-01-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Nat.Struct.Biol., 7, 2000
1GC6
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BU of 1gc6 by Molmil
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE
分子名称: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN
著者Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
登録日2000-07-21
公開日2000-09-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GC7
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BU of 1gc7 by Molmil
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN
分子名称: RADIXIN
著者Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
登録日2000-07-21
公開日2000-09-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1H4R
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BU of 1h4r by Molmil
Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein.
分子名称: MERLIN, SULFATE ION
著者Cooper, D.R, Kang, B.S, Sheffield, P, Devedjiev, Y, Derewenda, Z.S.
登録日2001-05-14
公開日2002-01-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product.
Acta Crystallogr.,Sect.D, 58, 2002
1ISN
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BU of 1isn by Molmil
Crystal structure of merlin FERM domain
分子名称: merlin
著者Shimizu, T, Seto, A, Maita, N, Hamada, K, Tsukita, S, Tsukita, S, Hakoshima, T.
登録日2001-12-13
公開日2002-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
J.Biol.Chem., 277, 2002

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