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4V2A
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human Unc5A ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NETRIN RECEPTOR UNC5A
著者Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
登録日2014-10-08
公開日2014-11-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
7AHS
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BU of 7ahs by Molmil
titin-N2A Ig81-Ig83
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Isoform 5 of Titin, ...
著者Fleming, J.R, Mayans, O.
登録日2020-09-25
公開日2021-03-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The N2A region of titin has a unique structural configuration.
J.Gen.Physiol., 153, 2021
4V10
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BU of 4v10 by Molmil
Skelemin Association with alpha2b,beta3 Integrin: A Structural Model
分子名称: MYOMESIN-1
著者Gorbatyuk, V, Deshmukh, L, Nguyen, K, Vinogradova, O.
登録日2014-09-19
公開日2014-10-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Skelemin Association with Alphaiibbeta3 Integrin: A Structural Model.
Biochemistry, 53, 2014
6SDB
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BU of 6sdb by Molmil
Chimeric titin Z1Z2 functionalized with a KLER exogenous peptide from decorin
分子名称: 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ...
著者Fleming, J.R, Hill, C, Mayans, O.M.
登録日2019-07-26
公開日2019-09-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The ZT Biopolymer: A Self-Assembling Protein Scaffold for Stem Cell Applications.
Int J Mol Sci, 20, 2019
7LU6
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BU of 7lu6 by Molmil
Crystal structure of the mouse Kirrel3 D1 homodimer
分子名称: Kin of IRRE-like protein 3, SODIUM ION
著者Roman, C.A, Pak, J.S, Wang, J, Ozkan, E.
登録日2021-02-21
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors.
Cell Rep, 37, 2021
6YJ0
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BU of 6yj0 by Molmil
Solution NMR structure of titin N2A region Ig domain I83
分子名称: Titin
著者Pfuhl, M, Gage, M.
登録日2020-04-02
公開日2021-04-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Titin N2A Region Ig Domain I83 and Its Interaction with Metal Ions.
J.Mol.Biol., 433, 2021
7R67
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BU of 7r67 by Molmil
Human obscurin Ig13
分子名称: Obscurin
著者Moncure, G.E, Wright, N.T.
登録日2021-06-22
公開日2022-11-02
最終更新日2023-03-22
実験手法SOLUTION NMR
主引用文献The N-terminus of obscurin is flexible in solution.
Proteins, 91, 2023
7R68
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BU of 7r68 by Molmil
Human obscurin Ig12
分子名称: Obscurin
著者Mauriello, G.E, Wright, N.T.
登録日2021-06-22
公開日2022-11-02
最終更新日2023-03-22
実験手法SOLUTION NMR
主引用文献The N-terminus of obscurin is flexible in solution.
Proteins, 91, 2023
7SJL
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Solution NMR Structure of Immunoglobulin-like Domain of Human Neuregulin-1
分子名称: Neuregulin-1
著者Eletsky, A, Kim, Y, Rogals, M.J, Prestegard, J.H.
登録日2021-10-18
公開日2022-05-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Validated determination of NRG1 Ig-like domain structure by mass spectrometry coupled with computational modeling
Commun Biol, 5, 2022
4QEG
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Crystal structure of domain I10 from titin (space group P41)
分子名称: CALCIUM ION, Titin
著者Bogomolovas, J, Labeit, S, Mayans, O.
登録日2014-05-16
公開日2015-07-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Exploration of the pathological potential of isolated mSNPs in titin: the cardiomyopathy-linked mutation T2580I
Open Biology, 2016
5OYJ
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BU of 5oyj by Molmil
Crystal structure of VEGFR-2 domains 4-5 in complex with DARPin D4b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CACODYLATE ION, ...
著者Piscitelli, C.L, Thieltges, K.M, Markovic-Mueller, S, Binz, H.K, Ballmer-Hofer, K.
登録日2017-09-10
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling.
Angiogenesis, 21, 2018
4UOW
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BU of 4uow by Molmil
Crystal structure of the titin M10-Obscurin Ig domain 1 complex
分子名称: CHLORIDE ION, Obscurin, SODIUM ION, ...
著者Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A.
登録日2014-06-10
公開日2014-12-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The Crystal Structure of the Human Titin:Obscurin Complex Reveals a Conserved Yet Specific Muscle M-Band Zipper Module.
J.Mol.Biol., 427, 2015
6HCI
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BU of 6hci by Molmil
Crystal structure of titin M3 domain
分子名称: SULFATE ION, Titin
著者Chatziefthimiou, S.D, Ugurlar, D, Wilmanns, M.
登録日2018-08-15
公開日2019-08-28
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural diversity in the atomic resolution 3D fingerprint of the titin M-band segment.
Plos One, 14, 2019
6NRX
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BU of 6nrx by Molmil
Crystal structure of DIP-eta IG1 homodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein eta, isoform B, ...
著者Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E.
登録日2019-01-24
公開日2019-02-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
6J6Y
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BU of 6j6y by Molmil
FGFR4 D2 - Fab complex
分子名称: Fab Heavy chain, Fab light chain, Fibroblast growth factor receptor 4
著者Takahashi, M, Hanzawa, H.
登録日2019-01-16
公開日2019-08-07
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity.
Mol.Cancer Ther., 18, 2019
5MO9
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BU of 5mo9 by Molmil
Structure of human TrkB receptor ligand binding domain in complex with the Fab frgment of antibody AB20
分子名称: AB20 Fab heavy chain, AB20 Fab light chain, BDNF/NT-3 growth factors receptor
著者Hoerer, S.
登録日2016-12-14
公開日2017-08-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Pharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell-Derived Neurons.
J. Pharmacol. Exp. Ther., 361, 2017
4CBP
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BU of 4cbp by Molmil
Crystal structure of neural ectodermal development factor IMP-L2.
分子名称: GLYCEROL, NEURAL/ECTODERMAL DEVELOPMENT FACTOR IMP-L2
著者Kulahin, N, Kristensen, O, Brzozowski, M, Schluckebier, G, Meyts, P.D.
登録日2013-10-15
公開日2014-10-29
最終更新日2019-05-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Analysis of Imp-L2 Function
To be Published
8P35
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BU of 8p35 by Molmil
Mutant human titin immunoglobulin-like 21 domain - C3575S
分子名称: Titin
著者Martinez-Martin, I, Crousilles, A, Mortensen, S.A, Alegre-Cebollada, J, Wilmanns, M.
登録日2023-05-17
公開日2023-11-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy.
Cell Rep, 42, 2023
8OVU
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BU of 8ovu by Molmil
Human titin immunoglobulin-like 21 domain
分子名称: MAGNESIUM ION, Titin
著者Martinez-Martin, I, Crousilles, A, Mortensen, S.A, Alegre-Cebollada, J, Wilmanns, M.
登録日2023-04-26
公開日2023-11-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy.
Cell Rep, 42, 2023
4C4K
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BU of 4c4k by Molmil
Crystal structure of the titin M10-Obscurin Ig domain 1 complex
分子名称: 1,2-ETHANEDIOL, OBSCURIN, TITIN
著者Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A.
登録日2013-09-05
公開日2014-09-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Crystal Structure of the Human Titin:Obscurin Complex Reveals a Conserved Yet Specific Muscle M-Band Zipper Module.
J.Mol.Biol., 427, 2015
6MG9
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BU of 6mg9 by Molmil
Human Obscurin Ig57 Domain
分子名称: Obscurin
著者Wright, N.T, Whitley, J.A.
登録日2018-09-13
公開日2019-02-06
最終更新日2019-11-27
実験手法SOLUTION NMR
主引用文献Obscurin is a semi-flexible molecule in solution.
Protein Sci., 28, 2019
3GRW
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BU of 3grw by Molmil
FGFR3 in complex with a Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
著者Wiesmann, C.
登録日2009-03-26
公開日2009-05-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice.
J.Clin.Invest., 119, 2009
1IE5
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BU of 1ie5 by Molmil
NMR STRUCTURE OF THE THIRD IMMUNOGLOBULIN DOMAIN FROM THE NEURAL CELL ADHESION MOLECULE.
分子名称: NEURAL CELL ADHESION MOLECULE
著者Atkins, A.R, Chung, J, Deechongkit, S, Little, E.B, Edelman, G.M, Wright, P.E, Cunningham, B.A, Dyson, H.J.
登録日2001-04-06
公開日2001-08-08
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding?
J.Mol.Biol., 311, 2001
3KVQ
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BU of 3kvq by Molmil
Crystal structure of VEGFR2 extracellular domain D7
分子名称: Vascular endothelial growth factor receptor 2
著者Yang, Y, Opatowsky, Y, Xie, P, Schlessinger, J.
登録日2009-11-30
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling
Proc.Natl.Acad.Sci.USA, 107, 2010
3KNB
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BU of 3knb by Molmil
Crystal structure of the titin C-terminus in complex with obscurin-like 1
分子名称: Obscurin-like protein 1, SULFATE ION, Titin
著者Sauer, F, Vahokoski, J, Wilmanns, M.
登録日2009-11-12
公開日2009-12-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin.
Embo Rep., 11, 2010

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