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8D9J
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BU of 8d9j by Molmil
SAMHD1-DNA complex
Descriptor: CALCIUM ION, DNA (5'-D(*CP*AP*AP*TP*G)-3'), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
Authors:Hollis, T.J, Batalis, S.M.
Deposit date:2022-06-10
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:SAMHD1-DNA complex
To Be Published
8P2M
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BU of 8p2m by Molmil
C. elegans TIR-1 protein.
Descriptor: NAD(+) hydrolase tir-1
Authors:Isupov, M.N, Opatowsky, Y.
Deposit date:2023-05-16
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
8P2L
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BU of 8p2l by Molmil
A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain.
Descriptor: NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Isupov, M.N, Opatowsky, Y.
Deposit date:2023-05-16
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
8TDW
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BU of 8tdw by Molmil
ssRNA bound SAMHD1 T open
Descriptor: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, RNA (5'-R(P*CP*CP*GP*AP*CP*C)-3'), ...
Authors:Sung, M, Huynh, K, Han, S.
Deposit date:2023-07-05
Release date:2023-11-22
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Guanine-containing ssDNA and RNA induce dimeric and tetrameric structural forms of SAMHD1.
Nucleic Acids Res., 51, 2023
8TDV
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BU of 8tdv by Molmil
ssRNA bound SAMHD1 T closed
Descriptor: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, RNA (5'-R(P*CP*CP*GP*AP*CP*CP*C)-3'), ...
Authors:Sung, M, Huynh, K, Han, S.
Deposit date:2023-07-05
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Guanine-containing ssDNA and RNA induce dimeric and tetrameric structural forms of SAMHD1.
Nucleic Acids Res., 51, 2023
8BW9
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BU of 8bw9 by Molmil
Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYP
Descriptor: Connector enhancer of KSR protein CNK, Dual specificity mitogen-activated protein kinase kinase dSOR1, KSR, ...
Authors:Maisonneuve, P, Fronzes, R, Sicheri, F.
Deposit date:2022-12-06
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction.
Nat.Struct.Mol.Biol., 2024
8BW8
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BU of 8bw8 by Molmil
Crystal structure of the dCNK-SAM-CRIC-PDZ/dHYP-SAM complex
Descriptor: Connector enhancer of KSR protein CNK, GLYCEROL, Protein aveugle
Authors:Maisonneuve, P, Kurinov, I, Sicheri, F.
Deposit date:2022-12-06
Release date:2024-02-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction.
Nat.Struct.Mol.Biol., 2024

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