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2X1G
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Crystal structure of Importin13 - Mago-Y14 complex
分子名称: CADMUS, PROTEIN MAGO NASHI, RNA-BINDING PROTEIN 8A
著者Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E.
登録日2009-12-23
公開日2010-02-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13.
Mol.Cell, 37, 2010
3A6P
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Crystal structure of Exportin-5:RanGTP:pre-miRNA complex
分子名称: 13-mer peptide, Exportin-5, GTP-binding nuclear protein Ran, ...
著者Okada, C, Yamashita, E, Lee, S.J, Shibata, S, Katahira, J, Nakagawa, A, Yoneda, Y, Tsukihara, T.
登録日2009-09-07
公開日2009-12-08
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献A high-resolution structure of the pre-microRNA nuclear export machinery
Science, 326, 2009
3GJX
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Crystal Structure of the Nuclear Export Complex CRM1-Snurportin1-RanGTP
分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ...
著者Monecke, T, Guettler, T, Neumann, P, Dickmanns, A, Goerlich, D, Ficner, R.
登録日2009-03-09
公開日2009-05-26
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP.
Science, 2009
3GB8
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Crystal structure of CRM1/Snurportin-1 complex
分子名称: Exportin-1, Snurportin-1
著者Dong, X, Biswas, A, Suel, K.E, Jackson, L.K, Martinez, R, Gu, H, Chook, Y.M.
登録日2009-02-19
公開日2009-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for leucine-rich nuclear export signal recognition by CRM1.
Nature, 458, 2009
3EA5
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Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics
分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ...
著者Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B.
登録日2008-08-24
公開日2008-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics.
J.Mol.Biol., 383, 2008
2P8Q
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Crystal Structure of human Importin beta bound to the Snurportin1 IBB-domain
分子名称: Importin beta-1 subunit, Snurportin-1
著者Mitrousis, G, Cingolani, G.
登録日2007-03-22
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}.
J.Biol.Chem., 283, 2008
2Q5D
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Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form
分子名称: Importin beta-1 subunit, Snurportin-1
著者Mitrousis, G, Cingolani, G.
登録日2007-05-31
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}.
J.Biol.Chem., 283, 2008
2QMR
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Karyopherin beta2/transportin
分子名称: Transportin-1
著者Cansizoglu, A.E, Chook, Y.M.
登録日2007-07-16
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational heterogeneity of karyopherin beta2 is segmental
Structure, 15, 2007
2Z5N
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Complex of Transportin 1 with hnRNP D NLS
分子名称: Heterogeneous nuclear ribonucleoprotein D0, Transportin-1
著者Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M.
登録日2007-07-14
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5J
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Free Transportin 1
分子名称: Transportin-1
著者Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M.
登録日2007-07-13
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5O
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Complex of Transportin 1 with JKTBP NLS
分子名称: Heterogeneous nuclear ribonucleoprotein D-like, Transportin-1
著者Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M.
登録日2007-07-14
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5K
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Complex of Transportin 1 with TAP NLS
分子名称: Nuclear RNA export factor 1, PHOSPHATE ION, Transportin-1
著者Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Kose, S, Imamoto, N, Sato, M.
登録日2007-07-14
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5M
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Complex of Transportin 1 with TAP NLS, crystal form 2
分子名称: Nuclear RNA export factor 1, Transportin-1
著者Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M.
登録日2007-07-14
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2OT8
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Karyopherin Beta2/Transportin-hnRNPM NLS Complex
分子名称: Heterogeneous nuclear ribonucleoprotein M, Transportin-1
著者Cansizoglu, A.E, Chook, Y.M.
登録日2007-02-07
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure-based design of a pathway-specific nuclear import inhibitor.
Nat.Struct.Mol.Biol., 14, 2007
2H4M
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Karyopherin Beta2/Transportin-M9NLS
分子名称: Heterogeneous nuclear ribonucleoprotein A1, Transportin-1
著者Chook, Y.M, Cansizoglu, A.E.
登録日2006-05-24
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Rules for nuclear localization sequence recognition by karyopherin beta 2.
Cell(Cambridge,Mass.), 126, 2006
1Z3H
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The exportin Cse1 in its cargo-free, cytoplasmic state
分子名称: Importin alpha re-exporter, MAGNESIUM ION
著者Cook, A, Fernandez, E, Lindner, D, Ebert, J, Schlenstedt, G, Conti, E.
登録日2005-03-12
公開日2005-05-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The structure of the nuclear export receptor cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding
Mol.Cell, 18, 2005
2BKU
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Kap95p:RanGTP complex
分子名称: GTP-BINDING NUCLEAR PROTEIN RAN, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN BETA-1 SUBUNIT, ...
著者Lee, S.J, Matsuura, Y, Liu, S.M, Stewart, M.
登録日2005-02-21
公開日2005-05-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for Nuclear Import Complex Dissociation by Rangtp
Nature, 435, 2005
1WA5
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Structure of the Cse1:Imp-alpha:RanGTP complex
分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ...
著者Stewart, M.
登録日2004-10-23
公開日2004-12-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
1UKL
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Crystal structure of Importin-beta and SREBP-2 complex
分子名称: Importin beta-1 subunit, Sterol regulatory element binding protein-2
著者Lee, S.J, Sekimoto, T, Yamashita, E, Nagoshi, E, Nakagawa, A, Imamoto, N, Yoshimura, M, Sakai, H, Tsukihara, T, Yoneda, Y.
登録日2003-08-26
公開日2003-12-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Structure of Importin-beta Bound to SREBP-2: Nuclear Import of a Transcription Factor
Science, 302, 2003
1O6O
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Importin Beta aa1-442 bound to five FxFG repeats from yeast Nsp1p. Second crystal form
分子名称: IMPORTIN BETA-1 SUBUNIT, NUCLEOPORIN NSP1
著者Bayliss, R, Stewart, M.
登録日2002-10-10
公開日2003-10-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta
J.Biol.Chem., 277, 2002
1O6P
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Importin Beta bound to a GLFG Nucleoporin peptide
分子名称: IMPORTIN BETA-1 SUBUNIT, SYNTHETIC GLFG PEPTIDE
著者Bayliss, R, Stewart, M.
登録日2002-10-10
公開日2003-04-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta
J.Biol.Chem., 277, 2002
1M5N
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Crystal structure of HEAT repeats (1-11) of importin b bound to the non-classical NLS(67-94) of PTHrP
分子名称: Importin beta-1 subunit, Parathyroid hormone-related protein
著者Cingolani, G, Bednenko, J, Gillespie, M.T, Gerace, L.
登録日2002-07-09
公開日2003-01-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta
Mol.Cell, 10, 2002
1GCJ
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N-TERMINAL FRAGMENT OF IMPORTIN-BETA
分子名称: IMPORTIN BETA
著者Lee, S.J, Imamoto, N, Sakai, H, Nakagawa, A, Kose, S, Koike, M, Yamamoto, M, Kumasaka, T, Yoneda, Y, Tsukihara, T.
登録日2000-07-31
公開日2000-10-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport.
J.Mol.Biol., 302, 2000
1F59
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IMPORTIN-BETA-FXFG NUCLEOPORIN COMPLEX
分子名称: FXFG NUCLEOPORIN REPEATS, IMPORTIN BETA-1
著者Bayliss, R, Littlewood, T, Stewart, M.
登録日2000-06-13
公開日2000-08-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking.
Cell(Cambridge,Mass.), 102, 2000
1IBR
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COMPLEX OF RAN WITH IMPORTIN BETA
分子名称: GTP-binding nuclear protein RAN, Importin beta-1 subunit, MAGNESIUM ION, ...
著者Vetter, I.R, Arndt, A, Kutay, U, Goerlich, D, Wittinghofer, A.
登録日1999-05-14
公開日1999-06-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural view of the Ran-Importin beta interaction at 2.3 A resolution
Cell(Cambridge,Mass.), 97, 1999

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