3A6P
Crystal structure of Exportin-5:RanGTP:pre-miRNA complex
Summary for 3A6P
Entry DOI | 10.2210/pdb3a6p/pdb |
Descriptor | Exportin-5, 13-mer peptide, GTP-binding nuclear protein Ran, ... (7 entities in total) |
Functional Keywords | exportin-5, pre-microrna, rangtp, nuclearexport, importin-beta family, nucleus, phosphoprotein, protein transport, rna-binding, rna-mediated gene silencing, transport, trna-binding, cell cycle, cell division, gtp-binding, isopeptide bond, mitosis, nucleotide-binding, protein transport-nuclear protein-rna complex, protein transport/nuclear protein/rna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q9HAV4 P62825 |
Total number of polymer chains | 10 |
Total formula weight | 355861.69 |
Authors | Okada, C.,Yamashita, E.,Lee, S.J.,Shibata, S.,Katahira, J.,Nakagawa, A.,Yoneda, Y.,Tsukihara, T. (deposition date: 2009-09-07, release date: 2009-12-08, Last modification date: 2012-04-25) |
Primary citation | Okada, C.,Yamashita, E.,Lee, S.J.,Shibata, S.,Katahira, J.,Nakagawa, A.,Yoneda, Y.,Tsukihara, T. A high-resolution structure of the pre-microRNA nuclear export machinery Science, 326:1275-1279, 2009 Cited by PubMed: 19965479DOI: 10.1126/science.1178705 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.92 Å) |
Structure validation
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