PDB: 23 resultsInfo pagesStatus searchChemie searchBIRD

---

5J45	Crystal structure of Shrub, fly ortholog of SNF7/CHMP4B Descriptor: GH13992p Authors: McMillan, B.J, Blacklow, S.C. Deposit date: 2016-03-31 Release date: 2016-07-20 Last modified: 2016-08-17 Method: X-RAY DIFFRACTION (2.758 Å) Cite: Electrostatic Interactions between Elongated Monomers Drive Filamentation of Drosophila Shrub, a Metazoan ESCRT-III Protein. Cell Rep, 16, 2016
6ZH3	Cryo-EM structure of ESCRT-III helical Vps24 filaments Descriptor: Vacuolar protein-sorting-associated protein 24 Authors: Huber, S.T, Mostafavi, S, Mortensen, S.A, Sachse, C. Deposit date: 2020-06-20 Release date: 2020-08-26 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure and assembly of ESCRT-III helical Vps24 filaments. Sci Adv, 6, 2020
2GD5	Structural basis for budding by the ESCRTIII factor CHMP3 Descriptor: Charged multivesicular body protein 3 Authors: Muziol, T.M, Pineda-Molina, E, Ravelli, R.B, Zamborlini, A, Usami, Y, Gottlinger, H, Weissenhorn, W. Deposit date: 2006-03-15 Release date: 2006-06-13 Last modified: 2017-10-18 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Basis for Budding by the ESCRT-III Factor CHMP3. Dev.Cell, 10, 2006
5FD7	X-ray Crystal Structure of ESCRT-III Snf7 core domain (conformation A) Descriptor: Vacuolar-sorting protein SNF7 Authors: Tang, S, Henne, W.M, Borbat, P.P, Buchkovich, N.J, Freed, J.H, Mao, Y, Fromme, J.C, Emr, S.D. Deposit date: 2015-12-15 Release date: 2015-12-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments. Elife, 4, 2015
5T8L	Crystal structure of Snf7 under 350 MPa Descriptor: Vacuolar-sorting protein SNF7 Authors: Huang, Q, Szebenyi, D. Deposit date: 2016-09-07 Release date: 2017-08-16 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of Snf7 under 350 MPa To Be Published
5FD9	X-ray Crystal Structure of ESCRT-III Snf7 core domain (conformation B) Descriptor: Vacuolar-sorting protein SNF7 Authors: Tang, S, Henne, W.M, Borbat, P.P, Buchkovich, N.J, Freed, J.H, Mao, Y, Fromme, J.C, Emr, S.D. Deposit date: 2015-12-15 Release date: 2015-12-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments. Elife, 4, 2015
7ZCH	CHMP2A-CHMP3 heterodimer (410 Angstrom diameter) Descriptor: Charged multivesicular body protein 2a, Charged multivesicular body protein 3 Authors: Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W. Deposit date: 2022-03-28 Release date: 2023-01-18 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage. Nat.Struct.Mol.Biol., 30, 2023
7ZCG	CHMP2A-CHMP3 heterodimer (430 Angstrom diameter) Descriptor: Charged multivesicular body protein 2a, Charged multivesicular body protein 3 Authors: Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W. Deposit date: 2022-03-28 Release date: 2023-01-18 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage. Nat.Struct.Mol.Biol., 30, 2023
5T8N	Crystal structure of Snf7 under 200 MPa Descriptor: Vacuolar-sorting protein SNF7 Authors: Huang, Q, Szebenyi, D. Deposit date: 2016-09-07 Release date: 2017-08-16 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.204 Å) Cite: Crystal structure of Snf7 under 200 MPa To Be Published
3FRT	The structure of human CHMP3 (residues 8 - 222). Descriptor: Charged multivesicular body protein 3 Authors: Schubert, H.L, McCullough, J, Hill, C.P, Sundquist, W.I. Deposit date: 2009-01-08 Release date: 2009-06-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (4 Å) Cite: Structural basis for ESCRT-III protein autoinhibition. Nat.Struct.Mol.Biol., 16, 2009
3FRV	Structure of Human CHMP3 (residues 1-150) Descriptor: Charged multivesicular body protein 3 Authors: Hill, C.P, Schubert, H.L, McCullough, J, Sundquist, W.I. Deposit date: 2009-01-08 Release date: 2009-06-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Structural basis for ESCRT-III protein autoinhibition. Nat.Struct.Mol.Biol., 16, 2009
4ABM	Crystal Structure of CHMP4B hairpin Descriptor: CHARGED MULTIVESICULAR BODY PROTEIN 4B Authors: Martinelli, N, Hartlieb, B, Usami, Y, Sabin, C, Dordor, A, Ribeiro, E.A, Gottlinger, H, Weissenhorn, W. Deposit date: 2011-12-08 Release date: 2012-05-09 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Cc2D1A is a Regulator of Escrt-III Chmp4B. J.Mol.Biol., 419, 2012
6TZ9	CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B only Descriptor: Charged multivesicular body protein 1b Authors: Nguyen, H.C, Frost, A. Deposit date: 2019-08-11 Release date: 2020-04-08 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Membrane constriction and thinning by sequential ESCRT-III polymerization. Nat.Struct.Mol.Biol., 27, 2020
4TXR	Crystal structure of LIP5 N-terminal domain complexed with CHMP1B MIM and CHMP5 MIM Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Charged multivesicular body protein 1b, ... Authors: Vild, C.J, Xu, Z. Deposit date: 2014-07-04 Release date: 2015-02-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1 Å) Cite: A Novel Mechanism of Regulating the ATPase VPS4 by Its Cofactor LIP5 and the Endosomal Sorting Complex Required for Transport (ESCRT)-III Protein CHMP5. J.Biol.Chem., 290, 2015
6E8G	CryoEM reconstruction of IST1-CHMP1B copolymer filament bound to ssDNA at 2.9 Angstrom resolution Descriptor: Charged multivesicular body protein 1b, IST1 homolog Authors: Talledge, N, Frost, A, McCullough, J. Deposit date: 2018-07-29 Release date: 2018-08-15 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: The ESCRT-III proteins IST1 and CHMP1B assemble around nucleic acids Biorxiv, 2018
3JC1	Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer Descriptor: Charged multivesicular body protein 1b, Increased Sodium Tolerance 1 (IST1) Authors: McCullough, J, Clippinger, A.K, Talledge, N, Skowyra, M.L, Saunders, M.G, Naismith, T.V, Colf, L.A, Afonine, P, Arthur, C, Sundquist, W.I, Hanson, P.I, Frost, A. Deposit date: 2015-11-09 Release date: 2015-12-16 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structure and membrane remodeling activity of ESCRT-III helical polymers. Science, 350, 2015
5VO5	Crystal structure of Lgd-Shrub complex, single chain fusion Descriptor: Coiled-coil and C2 domain-containing protein 1-like,GH13992p Authors: McMillan, B.J, Seegar, T.C.M, Blacklow, S.C. Deposit date: 2017-05-02 Release date: 2017-06-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.004 Å) Cite: Structural Basis for Regulation of ESCRT-III Complexes by Lgd. Cell Rep, 19, 2017
2LUH	NMR structure of the Vta1-Vps60 complex Descriptor: Vacuolar protein sorting-associated protein VTA1, Vacuolar protein-sorting-associated protein 60 Authors: Yang, Z, Vild, C, Ju, J, Zhang, X, Liu, J, Shen, J, Zhao, B, Lan, W, Gong, F, Liu, M, Cao, C, Xu, Z. Deposit date: 2012-06-13 Release date: 2012-11-07 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structural Basis of Molecular Recognition between ESCRT-III-like Protein Vps60 and AAA-ATPase Regulator Vta1 in the Multivesicular Body Pathway. J.Biol.Chem., 287, 2012
2LXM	Lip5-chmp5 Descriptor: Charged multivesicular body protein 5, Vacuolar protein sorting-associated protein VTA1 homolog Authors: Skalicky, J.J, Sundquist, W.I. Deposit date: 2012-08-29 Release date: 2012-11-28 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Interactions of the Human LIP5 Regulatory Protein with Endosomal Sorting Complexes Required for Transport. J.Biol.Chem., 287, 2012
6TZ4	CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (right-handed) Descriptor: Charged multivesicular body protein 1b, IST1 homolog Authors: Nguyen, H.C, Frost, A. Deposit date: 2019-08-10 Release date: 2020-04-08 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Membrane constriction and thinning by sequential ESCRT-III polymerization. Nat.Struct.Mol.Biol., 27, 2020
6TZ5	CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (left-handed) Descriptor: Charged multivesicular body protein 1b, IST1 homolog Authors: Nguyen, H.C, Frost, A. Deposit date: 2019-08-10 Release date: 2020-04-08 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Membrane constriction and thinning by sequential ESCRT-III polymerization. Nat.Struct.Mol.Biol., 27, 2020
3UM3	Crystal structure of the Brox Bro1 domain in complex with the C-terminal tail of CHMP4B Descriptor: BRO1 domain-containing protein BROX, Charged multivesicular body protein 4b Authors: Jiang, J.S, Mu, R.L, Xiao, T. Deposit date: 2011-11-12 Release date: 2012-04-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B. Structure, 20, 2012
2Z2W	Human Wee1 kinase complexed with inhibitor PF0335770 Descriptor: CHLORIDE ION, GLYCEROL, N-[4-(2-CHLOROPHENYL)-1,3-DIOXO-1,2,3,6-TETRAHYDROPYRROLO[3,4-C]CARBAZOL-9-YL]FORMAMIDE, ... Authors: Squire, C.J, Baker, E.N. Deposit date: 2007-05-29 Release date: 2008-05-06 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Synthesis and Structure-Activity Relationships of 9-Amino-4-(2-chlorophenyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones and Related Formamides as Inhibitors of the Wee1 and Chk1 Checkpoint Kinases To be Published