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5J45
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BU of 5j45 by Molmil
Crystal structure of Shrub, fly ortholog of SNF7/CHMP4B
分子名称: GH13992p
著者McMillan, B.J, Blacklow, S.C.
登録日2016-03-31
公開日2016-07-20
最終更新日2016-08-17
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Electrostatic Interactions between Elongated Monomers Drive Filamentation of Drosophila Shrub, a Metazoan ESCRT-III Protein.
Cell Rep, 16, 2016
6ZH3
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BU of 6zh3 by Molmil
Cryo-EM structure of ESCRT-III helical Vps24 filaments
分子名称: Vacuolar protein-sorting-associated protein 24
著者Huber, S.T, Mostafavi, S, Mortensen, S.A, Sachse, C.
登録日2020-06-20
公開日2020-08-26
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and assembly of ESCRT-III helical Vps24 filaments.
Sci Adv, 6, 2020
2GD5
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BU of 2gd5 by Molmil
Structural basis for budding by the ESCRTIII factor CHMP3
分子名称: Charged multivesicular body protein 3
著者Muziol, T.M, Pineda-Molina, E, Ravelli, R.B, Zamborlini, A, Usami, Y, Gottlinger, H, Weissenhorn, W.
登録日2006-03-15
公開日2006-06-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Budding by the ESCRT-III Factor CHMP3.
Dev.Cell, 10, 2006
5FD7
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BU of 5fd7 by Molmil
X-ray Crystal Structure of ESCRT-III Snf7 core domain (conformation A)
分子名称: Vacuolar-sorting protein SNF7
著者Tang, S, Henne, W.M, Borbat, P.P, Buchkovich, N.J, Freed, J.H, Mao, Y, Fromme, J.C, Emr, S.D.
登録日2015-12-15
公開日2015-12-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments.
Elife, 4, 2015
5T8L
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BU of 5t8l by Molmil
Crystal structure of Snf7 under 350 MPa
分子名称: Vacuolar-sorting protein SNF7
著者Huang, Q, Szebenyi, D.
登録日2016-09-07
公開日2017-08-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Snf7 under 350 MPa
To Be Published
5FD9
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BU of 5fd9 by Molmil
X-ray Crystal Structure of ESCRT-III Snf7 core domain (conformation B)
分子名称: Vacuolar-sorting protein SNF7
著者Tang, S, Henne, W.M, Borbat, P.P, Buchkovich, N.J, Freed, J.H, Mao, Y, Fromme, J.C, Emr, S.D.
登録日2015-12-15
公開日2015-12-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments.
Elife, 4, 2015
7ZCH
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BU of 7zch by Molmil
CHMP2A-CHMP3 heterodimer (410 Angstrom diameter)
分子名称: Charged multivesicular body protein 2a, Charged multivesicular body protein 3
著者Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W.
登録日2022-03-28
公開日2023-01-18
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
7ZCG
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BU of 7zcg by Molmil
CHMP2A-CHMP3 heterodimer (430 Angstrom diameter)
分子名称: Charged multivesicular body protein 2a, Charged multivesicular body protein 3
著者Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W.
登録日2022-03-28
公開日2023-01-18
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
5T8N
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BU of 5t8n by Molmil
Crystal structure of Snf7 under 200 MPa
分子名称: Vacuolar-sorting protein SNF7
著者Huang, Q, Szebenyi, D.
登録日2016-09-07
公開日2017-08-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Crystal structure of Snf7 under 200 MPa
To Be Published
3FRT
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BU of 3frt by Molmil
The structure of human CHMP3 (residues 8 - 222).
分子名称: Charged multivesicular body protein 3
著者Schubert, H.L, McCullough, J, Hill, C.P, Sundquist, W.I.
登録日2009-01-08
公開日2009-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis for ESCRT-III protein autoinhibition.
Nat.Struct.Mol.Biol., 16, 2009
3FRV
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BU of 3frv by Molmil
Structure of Human CHMP3 (residues 1-150)
分子名称: Charged multivesicular body protein 3
著者Hill, C.P, Schubert, H.L, McCullough, J, Sundquist, W.I.
登録日2009-01-08
公開日2009-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural basis for ESCRT-III protein autoinhibition.
Nat.Struct.Mol.Biol., 16, 2009
4ABM
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BU of 4abm by Molmil
Crystal Structure of CHMP4B hairpin
分子名称: CHARGED MULTIVESICULAR BODY PROTEIN 4B
著者Martinelli, N, Hartlieb, B, Usami, Y, Sabin, C, Dordor, A, Ribeiro, E.A, Gottlinger, H, Weissenhorn, W.
登録日2011-12-08
公開日2012-05-09
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cc2D1A is a Regulator of Escrt-III Chmp4B.
J.Mol.Biol., 419, 2012
6TZ9
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BU of 6tz9 by Molmil
CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B only
分子名称: Charged multivesicular body protein 1b
著者Nguyen, H.C, Frost, A.
登録日2019-08-11
公開日2020-04-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
4TXR
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BU of 4txr by Molmil
Crystal structure of LIP5 N-terminal domain complexed with CHMP1B MIM and CHMP5 MIM
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Charged multivesicular body protein 1b, ...
著者Vild, C.J, Xu, Z.
登録日2014-07-04
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献A Novel Mechanism of Regulating the ATPase VPS4 by Its Cofactor LIP5 and the Endosomal Sorting Complex Required for Transport (ESCRT)-III Protein CHMP5.
J.Biol.Chem., 290, 2015
6E8G
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BU of 6e8g by Molmil
CryoEM reconstruction of IST1-CHMP1B copolymer filament bound to ssDNA at 2.9 Angstrom resolution
分子名称: Charged multivesicular body protein 1b, IST1 homolog
著者Talledge, N, Frost, A, McCullough, J.
登録日2018-07-29
公開日2018-08-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The ESCRT-III proteins IST1 and CHMP1B assemble around nucleic acids
Biorxiv, 2018
3JC1
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BU of 3jc1 by Molmil
Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer
分子名称: Charged multivesicular body protein 1b, Increased Sodium Tolerance 1 (IST1)
著者McCullough, J, Clippinger, A.K, Talledge, N, Skowyra, M.L, Saunders, M.G, Naismith, T.V, Colf, L.A, Afonine, P, Arthur, C, Sundquist, W.I, Hanson, P.I, Frost, A.
登録日2015-11-09
公開日2015-12-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure and membrane remodeling activity of ESCRT-III helical polymers.
Science, 350, 2015
5VO5
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BU of 5vo5 by Molmil
Crystal structure of Lgd-Shrub complex, single chain fusion
分子名称: Coiled-coil and C2 domain-containing protein 1-like,GH13992p
著者McMillan, B.J, Seegar, T.C.M, Blacklow, S.C.
登録日2017-05-02
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Structural Basis for Regulation of ESCRT-III Complexes by Lgd.
Cell Rep, 19, 2017
2LUH
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BU of 2luh by Molmil
NMR structure of the Vta1-Vps60 complex
分子名称: Vacuolar protein sorting-associated protein VTA1, Vacuolar protein-sorting-associated protein 60
著者Yang, Z, Vild, C, Ju, J, Zhang, X, Liu, J, Shen, J, Zhao, B, Lan, W, Gong, F, Liu, M, Cao, C, Xu, Z.
登録日2012-06-13
公開日2012-11-07
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Basis of Molecular Recognition between ESCRT-III-like Protein Vps60 and AAA-ATPase Regulator Vta1 in the Multivesicular Body Pathway.
J.Biol.Chem., 287, 2012
2LXM
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BU of 2lxm by Molmil
Lip5-chmp5
分子名称: Charged multivesicular body protein 5, Vacuolar protein sorting-associated protein VTA1 homolog
著者Skalicky, J.J, Sundquist, W.I.
登録日2012-08-29
公開日2012-11-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Interactions of the Human LIP5 Regulatory Protein with Endosomal Sorting Complexes Required for Transport.
J.Biol.Chem., 287, 2012
6TZ4
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BU of 6tz4 by Molmil
CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (right-handed)
分子名称: Charged multivesicular body protein 1b, IST1 homolog
著者Nguyen, H.C, Frost, A.
登録日2019-08-10
公開日2020-04-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6TZ5
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BU of 6tz5 by Molmil
CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (left-handed)
分子名称: Charged multivesicular body protein 1b, IST1 homolog
著者Nguyen, H.C, Frost, A.
登録日2019-08-10
公開日2020-04-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
3UM3
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BU of 3um3 by Molmil
Crystal structure of the Brox Bro1 domain in complex with the C-terminal tail of CHMP4B
分子名称: BRO1 domain-containing protein BROX, Charged multivesicular body protein 4b
著者Jiang, J.S, Mu, R.L, Xiao, T.
登録日2011-11-12
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B.
Structure, 20, 2012
2Z2W
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BU of 2z2w by Molmil
Human Wee1 kinase complexed with inhibitor PF0335770
分子名称: CHLORIDE ION, GLYCEROL, N-[4-(2-CHLOROPHENYL)-1,3-DIOXO-1,2,3,6-TETRAHYDROPYRROLO[3,4-C]CARBAZOL-9-YL]FORMAMIDE, ...
著者Squire, C.J, Baker, E.N.
登録日2007-05-29
公開日2008-05-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Synthesis and Structure-Activity Relationships of 9-Amino-4-(2-chlorophenyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones and Related Formamides as Inhibitors of the Wee1 and Chk1 Checkpoint Kinases
To be Published

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件を2024-05-01に公開中

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