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1ZM4
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Structure of the eEF2-ETA-bTAD complex
分子名称: BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, Elongation factor 2, exotoxin A
著者Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R.
登録日2005-05-10
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
Nature, 436, 2005
1ZM2
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Structure of ADP-ribosylated eEF2 in complex with catalytic fragment of ETA
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Exotoxin A
著者Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R.
登録日2005-05-10
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
Nature, 436, 2005
1ZO1
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IF2, IF1, and tRNA fitted to cryo-EM data OF E. COLI 70S initiation complex
分子名称: P/I-site tRNA, translation Initiation Factor 1, translation initiation factor 2
著者Allen, G.S, Zavialov, A, Gursky, R, Ehrenberg, M, Frank, J.
登録日2005-05-12
公開日2005-06-14
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (13.8 Å)
主引用文献The Cryo-EM Structure of a Translation Initiation Complex from Escherichia coli.
Cell(Cambridge,Mass.), 121, 2005
2BV3
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Crystal structure of a mutant elongation factor G trapped with a GTP analogue
分子名称: ELONGATION FACTOR G, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T.
登録日2005-06-22
公開日2005-08-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of a Mutant Elongation Factor G Trapped with a GTP Analogue.
FEBS Lett., 579, 2005
2BVN
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E. coli EF-Tu:GDPNP in complex with the antibiotic enacyloxin IIa
分子名称: ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ...
著者Parmeggiani, A, Krab, I.M, Watanabe, T, Nielsen, R.C, Dahlberg, C, Nyborg, J, Nissen, P.
登録日2005-06-30
公開日2005-09-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics.
J.Biol.Chem., 281, 2006
1OB5
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T. aquaticus elongation factor EF-Tu complexed with the antibiotic enacyloxin IIa, a GTP analog, and Phe-tRNA
分子名称: ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ...
著者Dahlberg, C, Nielsen, R.C, Parmeggiani, A, Nyborg, J, Nissen, P.
登録日2003-01-24
公開日2005-10-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics.
J.Biol.Chem., 281, 2006
1ZUN
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Crystal Structure of a GTP-Regulated ATP Sulfurylase Heterodimer from Pseudomonas syringae
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Mougous, J.D, Lee, D.H, Hubbard, S.C, Schelle, M.W, Vocadlo, D.J, Berger, J.M, Bertozzi, C.R.
登録日2005-05-31
公開日2006-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis for g protein control of the prokaryotic ATP sulfurylase.
Mol.Cell, 21, 2006
2C78
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EF-Tu complexed with a GTP analog and the antibiotic pulvomycin
分子名称: (1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-DIHYDROXY-12,16,19-TRIMETHYL-11,22-DIOXOOX ACYCLODOCOSA-4,6,8,12,14,16,19-HEPTAEN-2-YL]-2,11-DIHYDROXY-1,10-DIMETHYL-9-OXOTRIDECA-3,5,7-TRIEN-1-YL 6-DEOXY-2,4-DI-O-METHYL-BETA-L-GALACTOPYRANOSIDE, ELONGATION FACTOR TU-A, MAGNESIUM ION, ...
著者Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P.
登録日2005-11-18
公開日2006-03-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
2C77
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EF-Tu complexed with a GTP analog and the antibiotic GE2270 A
分子名称: DI(HYDROXYETHYL)ETHER, ELONGATION FACTOR TU-B, MAGNESIUM ION, ...
著者Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P.
登録日2005-11-18
公開日2006-03-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
2FX3
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Crystal Structure Determination of E. coli Elongation Factor, Tu using a Twinned Data Set
分子名称: Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Heffron, S.E, Moeller, R, Jurnak, F.
登録日2006-02-03
公開日2006-03-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Solving the structure of Escherichia coli elongation factor Tu using a twinned data set.
Acta Crystallogr.,Sect.D, 62, 2006
2B7B
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Yeast guanine nucleotide exchange factor eEF1Balpha K205A mutant in complex with eEF1A and GDP
分子名称: Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, elongation factor-1 beta
著者Pittman, Y.R, Valente, L, Jeppesen, M.G, Andersen, G.R, Patel, S, Kinzy, T.G.
登録日2005-10-04
公開日2006-05-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha
J.Biol.Chem., 281, 2006
2B7C
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Yeast guanine nucleotide exchange factor eEF1Balpha K205A mutant in complex with eEF1A
分子名称: Elongation factor 1-alpha, elongation factor-1 beta
著者Pittman, Y.R, Valente, L, Jeppesen, M.G, Andersen, G.R, Patel, S, Kinzy, T.G.
登録日2005-10-04
公開日2006-05-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha
J.Biol.Chem., 281, 2006
2D74
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Crystal structure of translation initiation factor aIF2betagamma heterodimer
分子名称: Translation initiation factor 2 beta subunit, Translation initiation factor 2 gamma subunit, ZINC ION
著者Sokabe, M, Yao, M, Sakai, N, Toya, S, Tanaka, I.
登録日2005-11-16
公開日2006-07-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region.
Proc.Natl.Acad.Sci.USA, 103, 2006
2DCU
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Crystal structure of translation initiation factor aIF2betagamma heterodimer with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Translation initiation factor 2 beta subunit, ...
著者Sokabe, M, Yao, M, Sakai, N, Toya, S, Tanaka, I.
登録日2006-01-16
公開日2006-07-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region.
Proc.Natl.Acad.Sci.USA, 103, 2006
2HDN
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Trypsin-modified Elongation Factor Tu in complex with tetracycline at 2.8 Angstrom resolution
分子名称: Elongation factor EF-Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F.
登録日2006-06-20
公開日2006-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
2HCJ
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Trypsin-modified Elongation Factor Tu in complex with tetracycline
分子名称: GLYOXYLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F.
登録日2006-06-16
公開日2006-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
2E1R
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Structure of eEF2 in complex with a sordarin derivative
分子名称: (1S,4S,5S,6R,9S,11S)-6-CHLORO-9-FORMYL-13-ISOPROPYL-5-METHYL-2-({[(3AR,5R,7R ,7AS)-7-METHYL-3-METHYLENEHEXAHYDRO-2H-FURO[2,3-C]PYRAN-5-YL]OXY}METHYL)TETR ACYCLO[7.4.0.02,11.04,8]TRIDEC-12-ENE-1-CARBOXYLIC ACI, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE
著者Soe, R, Mosley, R.T, Andersen, G.R.
登録日2006-10-27
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2
J.Biol.Chem., 282, 2007
2NPF
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Structure of eEF2 in complex with moriniafungin
分子名称: (1S,4R,5R,9S,11S)-2-({[(2S,5R,6R,7R,9S,10R)-2-(7-CARBOXYHEPTYL)-6-HYDROXY-10-METHOXY-9-METHYL-3-OXO-1,4,8-TRIOXASPIRO[4 .5]DEC-7-YL]OXY}METHYL)-9-FORMYL-13-ISOPROPYL-5-METHYLTETRACYCLO[7.4.0.02,11.04.8]TRIDEC-12-ENE-1-CARBOXYLIC ACID, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE
著者Soe, R, Mosley, R.T, Andersen, G.R.
登録日2006-10-27
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2
J.Biol.Chem., 282, 2007
2P8Z
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Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP:sordarin cryo-EM reconstruction
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Elongation factor Tu-B, ...
著者Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J.
登録日2007-03-23
公開日2007-05-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (8.9 Å)
主引用文献Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
2P8W
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Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction
分子名称: Elongation factor 2, Elongation factor Tu-B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J.
登録日2007-03-23
公開日2007-05-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (11.3 Å)
主引用文献Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
2P8X
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Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP cryo-EM reconstruction
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Elongation factor Tu-B, ...
著者Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J.
登録日2007-03-23
公開日2007-05-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
2P8Y
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Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDP:sordarin cryo-EM reconstruction
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J.
登録日2007-03-23
公開日2007-05-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (11.7 Å)
主引用文献Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
2H5E
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Crystal structure of E.coli polypeptide release factor RF3
分子名称: GUANOSINE-5'-DIPHOSPHATE, Peptide chain release factor RF-3
著者Song, H.W, Zhou, Z.H.
登録日2006-05-26
公開日2007-05-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
2O0F
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Docking of the modified RF3 X-ray structure into cryo-EM map of E.coli 70S ribosome bound with RF3
分子名称: Peptide chain release factor 3
著者Gao, H, Zhou, Z, Rawat, U, Huang, C, Bouakaz, L, Wang, C, Liu, Y, Zavialov, A, Gursky, R, Sanyal, S, Ehrenberg, M, Frank, J, Song, H.
登録日2006-11-27
公開日2007-07-24
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (15.5 Å)
主引用文献RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
2J7K
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Crystal structure of the T84A mutant EF-G:GDPCP complex
分子名称: ELONGATION FACTOR G, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Hansson, S, Logan, D.T.
登録日2006-10-12
公開日2007-10-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献New Insights Into the Role of the P-Loop Lysine: Implications from the Crystal Structure of a Mutant EF-G:Gdpcp Complex
To be Published

219869

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