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1D1N
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BU of 1d1n by Molmil
SOLUTION STRUCTURE OF THE FMET-TRNAFMET BINDING DOMAIN OF BECILLUS STEAROTHERMOPHILLUS TRANSLATION INITIATION FACTOR IF2
Descriptor: INITIATION FACTOR 2
Authors:Meunier, S, Spurio, S, Czisch, M, Wechselberger, R, Gueunneugues, M.
Deposit date:1999-09-20
Release date:2000-09-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the fMet-tRNA(fMet)-binding domain of B. stearothermophilus initiation factor IF2.
EMBO J., 19, 2000
3E1Y
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BU of 3e1y by Molmil
Crystal structure of human eRF1/eRF3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1
Authors:Cheng, Z, Lim, M, Kong, C, Song, H.
Deposit date:2008-08-05
Release date:2009-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural insights into eRF3 and stop codon recognition by eRF1
Genes Dev., 23, 2009
1MJ1
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BU of 1mj1 by Molmil
FITTING THE TERNARY COMPLEX OF EF-Tu/tRNA/GTP AND RIBOSOMAL PROTEINS INTO A 13 A CRYO-EM MAP OF THE COLI 70S RIBOSOME
Descriptor: Elongation Factor Tu, L11 ribosomal protein, Phe-tRNA, ...
Authors:Stark, H, Rodnina, M.V, Wieden, H.-J, Zemlin, F, Wintermeyer, W, Vanheel, M.
Deposit date:2002-08-26
Release date:2002-11-01
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Ribosome Interactions of Aminoacyl-tRNA and Elongation Factor TU in the Codon Recognition Complex
Nat.Struct.Biol., 9, 2002
6D9J
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BU of 6d9j by Molmil
Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1.
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Pisareva, V.P, Pisarev, A.V, Fernandez, I.S.
Deposit date:2018-04-30
Release date:2018-06-06
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES.
Elife, 7, 2018
7QTT
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BU of 7qtt by Molmil
Structural organization of a late activated human spliceosome (Baqr, core region)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Cretu, C, Pena, V.
Deposit date:2022-01-15
Release date:2023-05-10
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
4WQY
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BU of 4wqy by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the post-translocational state (without fusitic acid)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Lin, J, Gagnon, M.G, Steitz, T.A.
Deposit date:2014-10-22
Release date:2015-01-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
6O7K
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BU of 6o7k by Molmil
30S initiation complex
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Frank, J, Gonzalez Jr, R.L, kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M.
Deposit date:2019-03-08
Release date:2019-05-29
Last modified:2020-01-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Late steps in bacterial translation initiation visualized using time-resolved cryo-EM.
Nature, 570, 2019
3CB4
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BU of 3cb4 by Molmil
The Crystal Structure of LepA
Descriptor: GTP-binding protein lepA
Authors:Evans, R.N, Blaha, G, Bailey, S, Steitz, T.A.
Deposit date:2008-02-21
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of LepA, the ribosomal back translocase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2RDO
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BU of 2rdo by Molmil
50S subunit with EF-G(GDPNP) and RRF bound
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ...
Authors:Gao, N, Zavialov, A.V, Ehrenberg, M, Frank, J.
Deposit date:2007-09-24
Release date:2008-03-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.
J.Mol.Biol., 374, 2007
3MMP
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BU of 3mmp by Molmil
Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins
Descriptor: (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ...
Authors:Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R.
Deposit date:2010-04-20
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins.
Proc.Natl.Acad.Sci.USA, 107, 2010
6U43
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BU of 6u43 by Molmil
Crystal structure of Methanoperedens nitroreducens elongation factor 2 H595N bound to GMPPCP and magnesium (triclinic crystal form)
Descriptor: CHLORIDE ION, Elongation factor 2, MAGNESIUM ION, ...
Authors:Fenwick, M.K, Ealick, S.E.
Deposit date:2019-08-22
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of elongation factor 2 switching
Curr Res Struct Biol, 2, 2020
5OT7
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BU of 5ot7 by Molmil
Elongation factor G-ribosome complex captures in the absence of inhibitors.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mace, K, Giudice, E, Chat, S, Gillet, R.
Deposit date:2017-08-21
Release date:2018-02-14
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors.
Nucleic Acids Res., 46, 2018
6UCQ
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BU of 6ucq by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome recycling complex
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Zhou, D, Tanzawa, T, Gagnon, M.G, Lin, J.
Deposit date:2019-09-17
Release date:2019-12-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for ribosome recycling by RRF and tRNA.
Nat.Struct.Mol.Biol., 27, 2020
5OPD
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BU of 5opd by Molmil
Structure of phosphorylated EF-Tu in complex with GTP
Descriptor: Elongation factor Tu 1, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Garcia-Pino, A.
Deposit date:2017-08-09
Release date:2018-08-29
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of phosphorylated EF-Tu in complex with GTP
To Be Published
7LS1
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BU of 7ls1 by Molmil
80S ribosome from mouse bound to eEF2 (Class II)
Descriptor: 28S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Loerch, S, Smith, P.R, Kunder, N, Stanowick, A.D, Lou, T.-F, Campbell, Z.T.
Deposit date:2021-02-17
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
Nat Commun, 12, 2021
7LS2
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BU of 7ls2 by Molmil
80S ribosome from mouse bound to eEF2 (Class I)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Loerch, S, Smith, P.R, Kunder, N, Stanowick, A.D, Lou, T.-F, Campbell, Z.T.
Deposit date:2021-02-17
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
Nat Commun, 12, 2021
9BDP
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BU of 9bdp by Molmil
80S ribosome bound with angiogenin and complex of eEF1A and Ala-tRNAAla
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Loveland, A.B, Korostelev, A.A.
Deposit date:2024-04-12
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural mechanism of angiogenin activation by the ribosome.
Nature, 630, 2024
9AX8
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BU of 9ax8 by Molmil
70S initiation complex (tRNA-fMet M1, initiation factor 2 + CUG start codon)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
Deposit date:2024-03-06
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 2024
9FMD
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BU of 9fmd by Molmil
Integrative model of the human post-catalytic spliceosome (P-complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Rothe, P, Plaschka, C, Vorlaender, M.K.
Deposit date:2024-06-05
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism for the initiation of spliceosome disassembly.
Nature, 2024
7AAV
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BU of 7aav by Molmil
Human pre-Bact-2 spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ...
Authors:Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
Deposit date:2020-09-04
Release date:2020-12-09
Last modified:2020-12-30
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
6RA9
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BU of 6ra9 by Molmil
Novel structural features and post-translational modifications in eukaryotic elongation factor 1A2 from Oryctolagus cuniculus
Descriptor: Elongation factor 1-alpha 2, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Carriles, A.A, Hermoso, J, Gago, F.
Deposit date:2019-04-05
Release date:2020-06-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Cues for Understanding eEF1A2 Moonlighting.
Chembiochem, 22, 2021
6ZMW
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BU of 6zmw by Molmil
Structure of a human 48S translational initiation complex
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-07-04
Release date:2020-09-23
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
6ZYM
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BU of 6zym by Molmil
Human C Complex Spliceosome - High-resolution CORE
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Corepressor interacting with RBPJ 1, ...
Authors:Bertram, K, Kastner, B.
Deposit date:2020-08-02
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Mol.Cell, 80, 2020
4R71
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BU of 4r71 by Molmil
Structure of the Qbeta holoenzyme complex in the P1211 crystal form
Descriptor: 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu, ...
Authors:Gytz, H, Seweryn, P, Kutlubaeva, Z, Chetverin, A.B, Brodersen, D.E, Knudsen, C.R.
Deposit date:2014-08-26
Release date:2015-09-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural basis for RNA-genome recognition during bacteriophage Q beta replication.
Nucleic Acids Res., 43, 2015
4V4B
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BU of 4v4b by Molmil
Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ...
Authors:Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J.
Deposit date:2004-01-06
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (11.7 Å)
Cite:Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004

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