1XB2
| Crystal Structure of Bos taurus mitochondrial Elongation Factor Tu/Ts Complex | Descriptor: | Elongation factor Ts, mitochondrial, Elongation factor Tu | Authors: | Jeppesen, M.G, Navratil, T, Spremulli, L.L, Nyborg, J. | Deposit date: | 2004-08-27 | Release date: | 2004-11-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the Bovine Mitochondrial Elongation Factor Tu.Ts Complex J.Biol.Chem., 280, 2005
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4PC6
| Elongation factor Tu:Ts complex with bound GDPNP | Descriptor: | Elongation factor Ts, Elongation factor Tu, GLYCEROL, ... | Authors: | Thirup, S.S. | Deposit date: | 2014-04-14 | Release date: | 2015-05-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural outline of the detailed mechanism for elongation factor Ts-mediated guanine nucleotide exchange on elongation factor Tu. J.Struct.Biol., 191, 2015
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4LC0
| Identifying ligand binding hot spots in proteins using brominated fragments | Descriptor: | AMMONIUM ION, Elongation factor Tu-A, MAGNESIUM ION, ... | Authors: | Groftehauge, M.K, Therkelsen, M, Taaning, R, Skrydstrup, T, Morth, J.P, Nissen, P. | Deposit date: | 2013-06-21 | Release date: | 2013-09-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.221 Å) | Cite: | Identifying ligand-binding hot spots in proteins using brominated fragments. Acta Crystallogr.,Sect.F, 69, 2013
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4LBZ
| Identifying ligand binding hot spots in proteins using brominated fragments | Descriptor: | AMMONIUM ION, Elongation factor Tu-A, MAGNESIUM ION, ... | Authors: | Groftehauge, M.K, Therkelsen, M, Taaning, R, Skrydstrup, T, Morth, J.P, Nissen, P. | Deposit date: | 2013-06-21 | Release date: | 2013-09-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.223 Å) | Cite: | Identifying ligand-binding hot spots in proteins using brominated fragments. Acta Crystallogr.,Sect.F, 69, 2013
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8FR3
| E. coli EF-Tu in complex with KKL-55 | Descriptor: | 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M. | Deposit date: | 2023-01-06 | Release date: | 2023-09-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA. Mbio, 14, 2023
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4J0Q
| Crystal structure of Pseudomonas putida elongation factor Tu (EF-Tu) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Elongation factor Tu-A, ... | Authors: | Scotti, J.S, McDonough, M.A, Schofield, C.J. | Deposit date: | 2013-01-31 | Release date: | 2014-02-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.294 Å) | Cite: | Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation Proc.Natl.Acad.Sci.USA, 111, 2014
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5W75
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2BVN
| E. coli EF-Tu:GDPNP in complex with the antibiotic enacyloxin IIa | Descriptor: | ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ... | Authors: | Parmeggiani, A, Krab, I.M, Watanabe, T, Nielsen, R.C, Dahlberg, C, Nyborg, J, Nissen, P. | Deposit date: | 2005-06-30 | Release date: | 2005-09-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics. J.Biol.Chem., 281, 2006
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3VMF
| Archaeal protein | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Kobayashi, K, Saito, K, Ishitani, R, Ito, K, Nureki, O. | Deposit date: | 2011-12-12 | Release date: | 2012-07-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for translation termination by archaeal RF1 and GTP-bound EF1alpha complex Nucleic Acids Res., 40, 2012
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3WXM
| Crystal structure of archaeal Pelota and GTP-bound EF1 alpha complex | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Kobayashi, K, Ishitani, R, Nureki, O. | Deposit date: | 2014-08-04 | Release date: | 2014-09-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1 alpha complex Proc.Natl.Acad.Sci.USA, 107, 2010
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3WY9
| Crystal structure of a complex of the archaeal ribosomal stalk protein aP1 and the GDP-bound archaeal elongation factor aEF1alpha | Descriptor: | 50S ribosomal protein L12, Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE | Authors: | Ito, K, Honda, T, Suzuki, T, Miyoshi, T, Murakami, R, Yao, M, Uchiumi, T. | Deposit date: | 2014-08-22 | Release date: | 2014-12-24 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1 alpha. Nucleic Acids Res., 42, 2014
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4G5G
| ef-tu (Escherichia coli) complexed with nvp-ldu796 | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Palestrant, D. | Deposit date: | 2012-07-17 | Release date: | 2012-12-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Antibiotic optimization and chemical structure stabilization of thiomuracin A. J.Med.Chem., 55, 2012
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1R5B
| Crystal structure analysis of sup35 | Descriptor: | Eukaryotic peptide chain release factor GTP-binding subunit | Authors: | Kong, C, Song, H. | Deposit date: | 2003-10-10 | Release date: | 2004-05-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe Mol.Cell, 14, 2004
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1D8T
| CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COMPLEXED WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC | Descriptor: | ACETATE ION, ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Heffron, S.E, Jurnak, F. | Deposit date: | 1999-10-25 | Release date: | 2000-10-25 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of an EF-TU Complex with a Thiazolyl Peptide Antibiotic Determined at 2.35 A Resolution: Atomic Basis for Ge2270A Inhibition of EF-TU. Biochemistry, 39, 2000
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3WYA
| Crystal structure of GDP-bound EF1alpha from Pyrococcus horikoshii | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE | Authors: | Ito, K, Honda, T, Suzuki, T, Miyoshi, T, Murakami, R, Yao, M, Uchiumi, T. | Deposit date: | 2014-08-22 | Release date: | 2014-12-24 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1 alpha. Nucleic Acids Res., 42, 2014
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5I4Q
| Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (domains 2 and 3) | Descriptor: | CHLORIDE ION, Contact-dependent inhibitor A, Contact-dependent inhibitor I, ... | Authors: | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | Deposit date: | 2016-02-12 | Release date: | 2017-06-28 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs. Nucleic Acids Res., 45, 2017
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1IJE
| Nucleotide Exchange Intermediates in the eEF1A-eEF1Ba Complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, elongation factor 1-alpha, elongation factor 1-beta | Authors: | Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J. | Deposit date: | 2001-04-26 | Release date: | 2001-05-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex. Nat.Struct.Biol., 8, 2001
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3AVX
| Structure of viral RNA polymerase complex 5 | Descriptor: | 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... | Authors: | Takeshita, D, Tomita, K. | Deposit date: | 2011-03-08 | Release date: | 2012-01-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.406 Å) | Cite: | Molecular basis for RNA polymerization by Q beta replicase Nat.Struct.Mol.Biol., 19, 2012
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3U6K
| Ef-tu (escherichia coli) in complex with nvp-ldk733 | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Palestrant, D.J. | Deposit date: | 2011-10-12 | Release date: | 2012-02-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids. J.Med.Chem., 54, 2011
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6EZE
| The open conformation of E.coli Elongation Factor Tu in complex with GDPNP. | Descriptor: | DI(HYDROXYETHYL)ETHER, Elongation factor Tu 2, GLYCEROL, ... | Authors: | Johansen, J.S, Blaise, M, Thirup, S.S. | Deposit date: | 2017-11-15 | Release date: | 2018-08-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form. Nucleic Acids Res., 46, 2018
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1EFT
| THE CRYSTAL STRUCTURE OF ELONGATION FACTOR EF-TU FROM THERMUS AQUATICUS IN THE GTP CONFORMATION | Descriptor: | ELONGATION FACTOR TU, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Kjeldgaard, M, Nissen, P, Thirup, S, Nyborg, J. | Deposit date: | 1993-08-24 | Release date: | 1994-08-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation. Structure, 1, 1993
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1EFU
| ELONGATION FACTOR COMPLEX EF-TU/EF-TS FROM ESCHERICHIA COLI | Descriptor: | ELONGATION FACTOR TS, ELONGATION FACTOR TU | Authors: | Kawashima, T, Berthet-Colominas, C, Wulff, M, Cusack, S, Leberman, R. | Deposit date: | 1996-07-09 | Release date: | 1997-01-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution. Nature, 379, 1996
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1DG1
| WHOLE, UNMODIFIED, EF-TU(ELONGATION FACTOR TU). | Descriptor: | ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Abel, K, Yoder, M, Hilgenfeld, R, Jurnak, F. | Deposit date: | 1999-11-22 | Release date: | 1999-12-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | An alpha to beta conformational switch in EF-Tu. Structure, 4, 1996
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3MMP
| Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins | Descriptor: | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ... | Authors: | Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R. | Deposit date: | 2010-04-20 | Release date: | 2010-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins. Proc.Natl.Acad.Sci.USA, 107, 2010
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8G60
| mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-14 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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