1D8T

CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COMPLEXED WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC

Summary for 1D8T

Entry DOI	10.2210/pdb1d8t/pdb
Related	1E9W 1OLN 2C77 2JQ7 2ZJP 3CF5
Related PRD ID	PRD_000225
Descriptor	ELONGATION FACTOR TU, THIOCILLIN GE2270, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	hydrolase-antibiotic complex, thiopeptide, antibiotic, antibacterial, thiazole, oxazole, hydrolase, gtpase, translation elongation factor, protein synthesis, nucleotide-binding, phosphorylation, hydrolase/antibiotic
Biological source	ESCHERICHIA COLI More
Cellular location	Secreted : Q7M0J8
Total number of polymer chains	4
Total formula weight	92094.23
Authors	Heffron, S.E.,Jurnak, F. (deposition date: 1999-10-25, release date: 2000-10-25, Last modification date: 2017-11-01)
Primary citation	Heffron, S.E.,Jurnak, F. Structure of an EF-TU Complex with a Thiazolyl Peptide Antibiotic Determined at 2.35 A Resolution: Atomic Basis for Ge2270A Inhibition of EF-TU. Biochemistry, 39:37-, 2000 Cited by PubMed: 10625477 DOI: 10.1021/BI9913597 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation