2HCJ
| Trypsin-modified Elongation Factor Tu in complex with tetracycline | Descriptor: | GLYOXYLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F. | Deposit date: | 2006-06-16 | Release date: | 2006-10-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu. Acta Crystallogr.,Sect.D, 62, 2006
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2B7B
| Yeast guanine nucleotide exchange factor eEF1Balpha K205A mutant in complex with eEF1A and GDP | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, elongation factor-1 beta | Authors: | Pittman, Y.R, Valente, L, Jeppesen, M.G, Andersen, G.R, Patel, S, Kinzy, T.G. | Deposit date: | 2005-10-04 | Release date: | 2006-05-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha J.Biol.Chem., 281, 2006
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2B7C
| Yeast guanine nucleotide exchange factor eEF1Balpha K205A mutant in complex with eEF1A | Descriptor: | Elongation factor 1-alpha, elongation factor-1 beta | Authors: | Pittman, Y.R, Valente, L, Jeppesen, M.G, Andersen, G.R, Patel, S, Kinzy, T.G. | Deposit date: | 2005-10-04 | Release date: | 2006-05-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha J.Biol.Chem., 281, 2006
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2FX3
| Crystal Structure Determination of E. coli Elongation Factor, Tu using a Twinned Data Set | Descriptor: | Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Heffron, S.E, Moeller, R, Jurnak, F. | Deposit date: | 2006-02-03 | Release date: | 2006-03-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Solving the structure of Escherichia coli elongation factor Tu using a twinned data set. Acta Crystallogr.,Sect.D, 62, 2006
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2C78
| EF-Tu complexed with a GTP analog and the antibiotic pulvomycin | Descriptor: | (1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-DIHYDROXY-12,16,19-TRIMETHYL-11,22-DIOXOOX ACYCLODOCOSA-4,6,8,12,14,16,19-HEPTAEN-2-YL]-2,11-DIHYDROXY-1,10-DIMETHYL-9-OXOTRIDECA-3,5,7-TRIEN-1-YL 6-DEOXY-2,4-DI-O-METHYL-BETA-L-GALACTOPYRANOSIDE, ELONGATION FACTOR TU-A, MAGNESIUM ION, ... | Authors: | Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P. | Deposit date: | 2005-11-18 | Release date: | 2006-03-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu. Biochemistry, 45, 2006
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2C77
| EF-Tu complexed with a GTP analog and the antibiotic GE2270 A | Descriptor: | DI(HYDROXYETHYL)ETHER, ELONGATION FACTOR TU-B, MAGNESIUM ION, ... | Authors: | Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P. | Deposit date: | 2005-11-18 | Release date: | 2006-03-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu. Biochemistry, 45, 2006
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1OB5
| T. aquaticus elongation factor EF-Tu complexed with the antibiotic enacyloxin IIa, a GTP analog, and Phe-tRNA | Descriptor: | ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ... | Authors: | Dahlberg, C, Nielsen, R.C, Parmeggiani, A, Nyborg, J, Nissen, P. | Deposit date: | 2003-01-24 | Release date: | 2005-10-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics. J.Biol.Chem., 281, 2006
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2BVN
| E. coli EF-Tu:GDPNP in complex with the antibiotic enacyloxin IIa | Descriptor: | ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ... | Authors: | Parmeggiani, A, Krab, I.M, Watanabe, T, Nielsen, R.C, Dahlberg, C, Nyborg, J, Nissen, P. | Deposit date: | 2005-06-30 | Release date: | 2005-09-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics. J.Biol.Chem., 281, 2006
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1ZC8
| Coordinates of tmRNA, SmpB, EF-Tu and h44 fitted into Cryo-EM map of the 70S ribosome and tmRNA complex | Descriptor: | Elongation factor Tu, H2 16S rRNA, H2b d mRNA, ... | Authors: | Valle, M, Gillet, R, Kaur, S, Henne, A, Ramakrishnan, V, Frank, J. | Deposit date: | 2005-04-11 | Release date: | 2005-04-19 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (13 Å) | Cite: | Visualizing tmRNA Entry into a Stalled Ribosome Science, 300, 2003
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1XB2
| Crystal Structure of Bos taurus mitochondrial Elongation Factor Tu/Ts Complex | Descriptor: | Elongation factor Ts, mitochondrial, Elongation factor Tu | Authors: | Jeppesen, M.G, Navratil, T, Spremulli, L.L, Nyborg, J. | Deposit date: | 2004-08-27 | Release date: | 2004-11-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the Bovine Mitochondrial Elongation Factor Tu.Ts Complex J.Biol.Chem., 280, 2005
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1SKQ
| The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Vitagliano, L, Ruggiero, A, Masullo, M, Cantiello, P, Arcari, P, Zagari, A. | Deposit date: | 2004-03-05 | Release date: | 2004-07-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with magnesium and GDP. Biochemistry, 43, 2004
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1OB2
| E. coli elongation factor EF-Tu complexed with the antibiotic kirromycin, a GTP analog, and Phe-tRNA | Descriptor: | ELONGATION FACTOR TU, KIRROMYCIN, MAGNESIUM ION, ... | Authors: | Kristensen, O, Nissen, P, Nyborg, J. | Deposit date: | 2003-01-24 | Release date: | 2004-05-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Kirromycin Defines a Specific Domain Arrangement of Elongation Factor EF-TU To be Published
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1R5O
| crystal structure analysis of sup35 complexed with GMPPNP | Descriptor: | Eukaryotic peptide chain release factor GTP-binding subunit, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Kong, C, Song, H. | Deposit date: | 2003-10-11 | Release date: | 2004-05-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe Mol.Cell, 14, 2004
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1R5B
| Crystal structure analysis of sup35 | Descriptor: | Eukaryotic peptide chain release factor GTP-binding subunit | Authors: | Kong, C, Song, H. | Deposit date: | 2003-10-10 | Release date: | 2004-05-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe Mol.Cell, 14, 2004
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1R5N
| Crystal Structure Analysis of sup35 complexed with GDP | Descriptor: | Eukaryotic peptide chain release factor GTP-binding subunit, GUANOSINE-5'-DIPHOSPHATE | Authors: | Kong, C, Song, H. | Deposit date: | 2003-10-10 | Release date: | 2004-05-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe Mol.Cell, 14, 2004
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1QZD
| EF-Tu.kirromycin coordinates fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome | Descriptor: | Elongation factor Tu | Authors: | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | Deposit date: | 2003-09-16 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
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1MJ1
| FITTING THE TERNARY COMPLEX OF EF-Tu/tRNA/GTP AND RIBOSOMAL PROTEINS INTO A 13 A CRYO-EM MAP OF THE COLI 70S RIBOSOME | Descriptor: | Elongation Factor Tu, L11 ribosomal protein, Phe-tRNA, ... | Authors: | Stark, H, Rodnina, M.V, Wieden, H.-J, Zemlin, F, Wintermeyer, W, Vanheel, M. | Deposit date: | 2002-08-26 | Release date: | 2002-11-01 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (13 Å) | Cite: | Ribosome Interactions of Aminoacyl-tRNA and Elongation Factor TU in the
Codon Recognition Complex Nat.Struct.Biol., 9, 2002
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1LS2
| Fitting of EF-Tu and tRNA in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome | Descriptor: | Elongation Factor Tu, Phenylalanine transfer RNA | Authors: | Valle, M, Sengupta, J, Swami, N.K, Grassucci, R.A, Burkhardt, N, Nierhaus, K.H, Agrawal, R.K, Frank, J. | Deposit date: | 2002-05-16 | Release date: | 2002-06-26 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (16.799999 Å) | Cite: | Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process. EMBO J., 21, 2002
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1JNY
| Crystal structure of Sulfolobus solfataricus elongation factor 1 alpha in complex with GDP | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE | Authors: | Vitagliano, L, Masullo, M, Sica, F, Zagari, A, Bocchini, V. | Deposit date: | 2001-07-26 | Release date: | 2002-01-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with GDP reveals novel features in nucleotide binding and exchange. EMBO J., 20, 2001
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1HA3
| ELONGATION FACTOR TU IN COMPLEX WITH aurodox | Descriptor: | BETA-MERCAPTOETHANOL, ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Vogeley, L, Palm, G.J, Mesters, J.R, Hilgenfeld, R. | Deposit date: | 2001-03-26 | Release date: | 2001-05-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conformational Change of Elongation Factor TU Induced by Antibiotic Binding: Crystal Structure of the Complex between EF-TU:Gdp and Aurodox J.Biol.Chem., 276, 2001
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1IJE
| Nucleotide Exchange Intermediates in the eEF1A-eEF1Ba Complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, elongation factor 1-alpha, elongation factor 1-beta | Authors: | Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J. | Deposit date: | 2001-04-26 | Release date: | 2001-05-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex. Nat.Struct.Biol., 8, 2001
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1IJF
| Nucleotide exchange mechanisms in the eEF1A-eEF1Ba complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, elongation factor 1-alpha, ... | Authors: | Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J. | Deposit date: | 2001-04-26 | Release date: | 2001-05-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex. Nat.Struct.Biol., 8, 2001
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1G7C
| YEAST EEF1A:EEF1BA IN COMPLEX WITH GDPNP | Descriptor: | ELONGATION FACTOR 1-ALPHA, ELONGATION FACTOR 1-BETA, GUANOSINE-5'-MONOPHOSPHATE | Authors: | Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J. | Deposit date: | 2000-11-10 | Release date: | 2000-12-06 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex. Nat.Struct.Biol., 8, 2001
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1D8T
| CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COMPLEXED WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC | Descriptor: | ACETATE ION, ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Heffron, S.E, Jurnak, F. | Deposit date: | 1999-10-25 | Release date: | 2000-10-25 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of an EF-TU Complex with a Thiazolyl Peptide Antibiotic Determined at 2.35 A Resolution: Atomic Basis for Ge2270A Inhibition of EF-TU. Biochemistry, 39, 2000
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1F60
| CRYSTAL STRUCTURE OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA | Descriptor: | ELONGATION FACTOR EEF1A, ELONGATION FACTOR EEF1BA | Authors: | Andersen, G.R, Pedersen, L, Valente, L, Kinzy, T.G, Nyborg, J. | Deposit date: | 2000-06-19 | Release date: | 2000-07-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha. Mol.Cell, 6, 2000
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