5IFS
| Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Roske, Y, Arumughan, A, Heinemann, U, Wanker, E. | 登録日 | 2016-02-26 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers. Nat Commun, 7, 2016
|
|
5GLF
| Structural insights into the interaction of p97 N-terminal domain and SHP motif in Derlin-1 rhomboid pseudoprotease | 分子名称: | Derlin-1, Transitional endoplasmic reticulum ATPase | 著者 | Lim, J.J, Lee, Y, Yoon, S.Y, Ly, T.T, Kang, J.Y, Youn, H.-S, An, J.Y, Lee, J.-G, Park, K.R, Kim, T.G, Yang, J.K, Jun, Y, Eom, S.H. | 登録日 | 2016-07-11 | 公開日 | 2016-11-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural insights into the interaction of human p97 N-terminal domain and SHP motif in Derlin-1 rhomboid pseudoprotease. FEBS Lett., 590, 2016
|
|
5B6C
| Structural Details of Ufd1 binding to p97 | 分子名称: | Peptide from Ubiquitin fusion degradation protein 1 homolog, Transitional endoplasmic reticulum ATPase | 著者 | Le, L.T.M, Yang, J.K. | 登録日 | 2016-05-26 | 公開日 | 2017-01-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural Details of Ufd1 Binding to p97 and Their Functional Implications in ER-Associated Degradation PLoS ONE, 11, 2016
|
|
5X4L
| Crystal structure of the UBX domain of human UBXD7 in complex with p97 N domain | 分子名称: | Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 7 | 著者 | Jiang, T, Li, Z, Wang, Y, Xu, M. | 登録日 | 2017-02-13 | 公開日 | 2017-03-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase Biochem. Biophys. Res. Commun., 486, 2017
|
|
5KIY
| p97 ND1-A232E in complex with VIMP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ... | 著者 | Tang, W.K, Xia, D. | 登録日 | 2016-06-17 | 公開日 | 2017-12-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structural basis for nucleotide-modulated p97 association with the ER membrane. Cell Discov, 3, 2017
|
|
5KIW
| p97 ND1-L198W in complex with VIMP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ... | 著者 | Tang, W.K, Xia, D. | 登録日 | 2016-06-17 | 公開日 | 2018-03-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | 主引用文献 | Structural basis for nucleotide-modulated p97 association with the ER membrane. Cell Discov, 3, 2017
|
|
6CHS
| Cdc48-Npl4 complex in the presence of ATP-gamma-S | 分子名称: | MAGNESIUM ION, Npl4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Kim, K.H, Bodnar, N.O, Walz, T, Rapoport, T.A. | 登録日 | 2018-02-22 | 公開日 | 2018-07-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4. Nat. Struct. Mol. Biol., 25, 2018
|
|
6MDO
| The D1 and D2 domain rings of NSF engaging the SNAP-25 N-terminus within the 20S supercomplex (focused refinement on D1/D2 rings, class 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Synaptosomal-associated protein 25, ... | 著者 | White, K.I, Zhao, M, Brunger, A.T. | 登録日 | 2018-09-04 | 公開日 | 2018-09-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural principles of SNARE complex recognition by the AAA+ protein NSF. Elife, 7, 2018
|
|
6MDP
| The D1 and D2 domain rings of NSF engaging the SNAP-25 N-terminus within the 20S supercomplex (focused refinement on D1/D2 rings, class 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Synaptosomal-associated protein 25, ... | 著者 | White, K.I, Zhao, M, Brunger, A.T. | 登録日 | 2018-09-04 | 公開日 | 2018-09-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural principles of SNARE complex recognition by the AAA+ protein NSF. Elife, 7, 2018
|
|
6MDN
| The 20S supercomplex engaging the SNAP-25 N-terminus (class 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-soluble NSF attachment protein, ... | 著者 | White, K.I, Zhao, M, Brunger, A.T. | 登録日 | 2018-09-04 | 公開日 | 2018-09-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural principles of SNARE complex recognition by the AAA+ protein NSF. Elife, 7, 2018
|
|
6MDM
| The 20S supercomplex engaging the SNAP-25 N-terminus (class 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-soluble NSF attachment protein, ... | 著者 | White, K.I, Zhao, M, Brunger, A.T. | 登録日 | 2018-09-04 | 公開日 | 2018-09-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural principles of SNARE complex recognition by the AAA+ protein NSF. Elife, 7, 2018
|
|
6IP2
| NSF-D1D2 part in the whole 20S complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Vesicle-fusing ATPase | 著者 | Huang, X, Sun, S, Wang, X, Fan, F, Zhou, Q, Sui, S.F. | 登録日 | 2018-11-01 | 公開日 | 2019-04-24 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Mechanistic insights into the SNARE complex disassembly. Sci Adv, 5, 2019
|
|
6OA9
| Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ... | 著者 | Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A. | 登録日 | 2019-03-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science, 365, 2019
|
|
6OAA
| Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ADP-BeFx, state 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | 著者 | Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A. | 登録日 | 2019-03-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science, 365, 2019
|
|
6OAB
| Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ADP-BeFx, state 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | 著者 | Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A. | 登録日 | 2019-03-15 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science, 365, 2019
|
|
6OPC
| Cdc48 Hexamer in a complex with substrate and Shp1(Ubx Domain) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | 著者 | Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S. | 登録日 | 2019-04-24 | 公開日 | 2019-07-10 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Science, 365, 2019
|
|
6OMB
| Cdc48 Hexamer (Subunits A to E) with substrate bound to the central pore | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | 著者 | Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S. | 登録日 | 2019-04-18 | 公開日 | 2019-07-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Science, 365, 2019
|
|
6HD3
| Common mode of remodeling AAA ATPases p97/CDC48 by their disassembly cofactors ASPL/PUX1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 48 homolog A, PHOSPHATE ION | 著者 | Heinemann, U, Roske, Y, Banchenko, S, Arumughan, A, Petrovic, S. | 登録日 | 2018-08-17 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Common Mode of Remodeling AAA ATPases p97/CDC48 by Their Disassembling Cofactors ASPL/PUX1. Structure, 27, 2019
|
|
6HD0
| |
7JY5
| Structure of human p97 in complex with ATPgammaS and Npl4/Ufd1 (masked around p97) | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2020-08-28 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative. Nat Commun, 12, 2021
|
|
7BPB
| |
7BP9
| Human AAA+ ATPase VCP mutant - T76E, ADP-bound form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Yang, C, Zhang, H. | 登録日 | 2020-03-21 | 公開日 | 2021-03-31 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
|
|
7BPA
| |
7BP8
| Human AAA+ ATPase VCP mutant - T76A, ADP-bound form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Yang, C, Zhang, H. | 登録日 | 2020-03-21 | 公開日 | 2021-03-31 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
|
|
7R7S
| p47-bound p97-R155H mutant with ATPgammaS | 分子名称: | NSFL1 cofactor p47, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. | 登録日 | 2021-06-25 | 公開日 | 2021-08-04 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (4.23 Å) | 主引用文献 | Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
|
|