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1PN5
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NMR structure of the NALP1 Pyrin domain (PYD)
分子名称: NACHT-, LRR- and PYD-containing protein 2
著者Hiller, S, Kohl, A, Fiorito, F, Herrmann, T, Wider, G, Tschopp, J, Grutter, M.G, Wuthrich, K.
登録日2003-06-12
公開日2003-10-07
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain
Structure, 11, 2003
1UCP
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BU of 1ucp by Molmil
NMR structure of the PYRIN domain of human ASC
分子名称: Apoptosis-associated speck-like protein containing a CARD
著者Liepinsh, E, Barbals, R, Dahl, E, Sharipo, A, Staub, E, Otting, G.
登録日2003-04-16
公開日2003-11-04
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
J.Mol.Biol., 332, 2003
2DBG
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BU of 2dbg by Molmil
Solution structure of the Pyrin (PAAD-DAPIN) domain in human Myeloid cell nuclear differentiation antigen
分子名称: Myeloid cell nuclear differentiation antigen
著者Saito, K, Inoue, M, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-15
公開日2006-06-15
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of the Pyrin (PAAD-DAPIN) domain in human Myeloid cell nuclear differentiation antigen
To be Published
2HM2
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BU of 2hm2 by Molmil
Solution structure of ASC2
分子名称: Pyrin-only protein 1
著者Natarajan, A, Ghose, R, Hill, J.M.
登録日2006-07-11
公開日2006-07-25
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structure and dynamics of ASC2, a pyrin domain-only protein that regulates inflammatory signaling
J.Biol.Chem., 281, 2006
2DO9
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BU of 2do9 by Molmil
Solution structure of the Pyrin/PAAD-DAPIN domain in mouse NALP10 (NACHT, leucine rich repeat and PYD containing 10)
分子名称: NACHT-, LRR- and PYD-containing protein 10
著者Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-28
公開日2006-10-28
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of the Pyrin/PAAD-DAPIN domain in mouse NALP10 (NACHT, leucine rich repeat and PYD containing 10)
To be Published
2YU0
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BU of 2yu0 by Molmil
Solution structures of the PAAD_DAPIN domain of mus musculus interferon-activatable protein 205
分子名称: Interferon-activable protein 205
著者Sato, M, Tochio, N, Koshiba, S, Watanabe, M, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2008-02-19
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structures of the PAAD_DAPIN domain of mus musculus interferon-activatable protein 205
To be Published
2KN6
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BU of 2kn6 by Molmil
Structure of full-length human ASC (Apoptosis-associated speck-like protein containing a CARD)
分子名称: Apoptosis-associated speck-like protein containing a CARD
著者De Alba, E.
登録日2009-08-16
公開日2009-09-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure and interdomain dynamics of apoptosis-associated speck-like protein containing a CARD (ASC)
J.Biol.Chem., 284, 2009
2KM6
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BU of 2km6 by Molmil
NMR structure of the NLRP7 Pyrin domain
分子名称: NACHT, LRR and PYD domains-containing protein 7
著者Pinheiro, A, Proell, M, Schwarzenbacher, R, Peti, W.
登録日2009-07-21
公開日2010-06-09
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of the NLRP7 pyrin domain: insight into pyrin-pyrin-mediated effector domain signaling in innate immunity.
J.Biol.Chem., 285, 2010
3QF2
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Crystal structure of NALP3 PYD
分子名称: NACHT, LRR and PYD domains-containing protein 3
著者Park, H.H, Bae, J.Y.
登録日2011-01-21
公開日2011-08-31
最終更新日2011-11-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly
J.Biol.Chem., 286, 2011
2L6A
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BU of 2l6a by Molmil
Three-dimensional structure of the N-terminal effector PYRIN domain of NLRP12
分子名称: NACHT, LRR and PYD domains-containing protein 12
著者Pinheiro, A.S, Peti, W.
登録日2010-11-17
公開日2011-11-02
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The NLRP12 pyrin domain: structure, dynamics, and functional insights.
J.Mol.Biol., 413, 2011
4EWI
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BU of 4ewi by Molmil
Crystal structure of the NLRP4 Pyrin domain
分子名称: CHLORIDE ION, NACHT, LRR and PYD domains-containing protein 4, ...
著者Eibl, C, Hessenberger, M, Puehringer, S, Page, R, Diederichs, K, Peti, W.
登録日2012-04-27
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural and Functional Analysis of the NLRP4 Pyrin Domain.
Biochemistry, 51, 2012
3VD8
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BU of 3vd8 by Molmil
Crystal structure of human AIM2 PYD domain with MBP fusion
分子名称: 1,2-ETHANEDIOL, Maltose-binding periplasmic protein, Interferon-inducible protein AIM2, ...
著者Jin, T.C, Perry, A, Smith, P, Xiao, T.S.
登録日2012-01-04
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.0685 Å)
主引用文献Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly.
J.Biol.Chem., 288, 2013
2M5V
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BU of 2m5v by Molmil
Three-dimensional structure of human NLRP10/PYNOD pyrin domain
分子名称: NACHT, LRR and PYD domains-containing protein 10
著者Su, M.Y, Chang, C.F, Chang, C.I.
登録日2013-03-11
公開日2013-04-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Three-Dimensional Structure of Human NLRP10/PYNOD Pyrin Domain Reveals a Homotypic Interaction Site Distinct from Its Mouse Homologue.
Plos One, 8, 2013
4O7Q
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Crystal Structure of the F27G AIM2 Pyrin Domain Mutant and Similarities of its Self-association to DED/DED Interactions
分子名称: Interferon-inducible protein AIM2
著者Lu, A, Kabaleeswaran, V, Wu, H.
登録日2013-12-26
公開日2014-02-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal Structure of the F27G AIM2 PYD Mutant and Similarities of Its Self-Association to DED/DED Interactions.
J.Mol.Biol., 426, 2014
3J63
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Unified assembly mechanism of ASC-dependent inflammasomes
分子名称: Apoptosis-associated speck-like protein containing a CARD
著者Lu, A, Magupalli, V.G, Ruan, J, Yin, Q, Atianand, M.K, Vos, M, Schroder, G.F, Fitzgerald, K.A, Wu, H, Egelman, E.H.
登録日2013-12-05
公開日2014-03-26
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes.
Cell(Cambridge,Mass.), 156, 2014
2MPC
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BU of 2mpc by Molmil
Solution structure of the pyrin domain of human Pyrin
分子名称: Pyrin
著者Soh, S.L, Smith, S.J, Hill, J.M.
登録日2014-05-15
公開日2014-07-16
最終更新日2022-08-24
実験手法SOLUTION NMR
主引用文献Identification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly.
J.Biol.Chem., 289, 2014
4N1J
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Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions
分子名称: GLYCEROL, NACHT, LRR and PYD domains-containing protein 14
著者Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H.
登録日2013-10-04
公開日2014-07-16
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions.
Acta Crystallogr.,Sect.D, 70, 2014
4N1L
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BU of 4n1l by Molmil
Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions
分子名称: NACHT, LRR and PYD domains-containing protein 14
著者Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H.
登録日2013-10-04
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.986 Å)
主引用文献Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions.
Acta Crystallogr.,Sect.D, 70, 2014
4N1K
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BU of 4n1k by Molmil
Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions
分子名称: NACHT, LRR and PYD domains-containing protein 14
著者Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H.
登録日2013-10-04
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions.
Acta Crystallogr.,Sect.D, 70, 2014
2N00
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BU of 2n00 by Molmil
NMR Solution structure of AIM2 PYD from Mus musculus
分子名称: Interferon-inducible protein AIM2
著者Hou, X, Niu, X.
登録日2015-03-01
公開日2015-05-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The NMR solution structure of AIM2 PYD domain from Mus musculus reveals a distinct alpha 2-alpha 3 helix conformation from its human homologues
Biochem.Biophys.Res.Commun., 461, 2015
2N1F
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BU of 2n1f by Molmil
Structure and assembly of the mouse ASC filament by combined NMR spectroscopy and cryo-electron microscopy
分子名称: Apoptosis-associated speck-like protein
著者Sborgi, L, Ravotti, F, Dandey, V, Dick, M, Mazur, A, Reckel, S, Chami, M, Scherer, S, Bockmann, A, Egelman, E, Stahlberg, H, Broz, P, Meier, B, Hiller, S.
登録日2015-04-01
公開日2015-10-14
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR
主引用文献Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 112, 2015
4QOB
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BU of 4qob by Molmil
Crystal structure of cPOP1
分子名称: Pyrin domain-containing protein 1
著者Park, H.H.
登録日2014-06-19
公開日2015-11-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of cPOP1
To be Published
2NAQ
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3D NMR solution structure of NLRP3 PYD
分子名称: NACHT, LRR and PYD domains-containing protein 3
著者de Alba, E, Oroz, J.
登録日2016-01-07
公開日2016-07-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献ASC Pyrin Domain Self-associates and Binds NLRP3 Protein Using Equivalent Binding Interfaces.
J.Biol.Chem., 291, 2016
5H7Q
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Crystal structure of human MNDA PYD domain with MBP tag
分子名称: ACETATE ION, MNDA PYD domain with MBP tag, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Jin, T.C, Xiao, T.S.
登録日2016-11-20
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
5WPZ
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Crystal structure of MNDA PYD with MBP tag
分子名称: MBP-hMNDA-PYD, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Jin, T.C, Xiao, T.S.
登録日2016-11-22
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017

 

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