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8Q7I
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BU of 8q7i by Molmil
PCNA from Chaetomium thermophilum in complex with Fen1 peptide
Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen, SODIUM ION
Authors:Alphey, M.S, Wolford, C.B, MacNeill, S.A.
Deposit date:2023-08-16
Release date:2023-12-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Canonical binding of Chaetomium thermophilum DNA polymerase delta / zeta subunit PolD3 and flap endonuclease Fen1 to PCNA.
Front Mol Biosci, 10, 2023
6KNC
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BU of 6knc by Molmil
PolD-PCNA-DNA (form B)
Descriptor: DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ...
Authors:Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y.
Deposit date:2019-08-05
Release date:2020-08-05
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Bmc Biol., 18, 2020
6KNB
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BU of 6knb by Molmil
PolD-PCNA-DNA (form A)
Descriptor: DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ...
Authors:Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y.
Deposit date:2019-08-05
Release date:2020-08-05
Last modified:2021-02-17
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Bmc Biol., 18, 2020
3V61
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BU of 3v61 by Molmil
Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164
Descriptor: BARIUM ION, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ...
Authors:Armstrong, A.A, Mohideen, F, Lima, C.D.
Deposit date:2011-12-18
Release date:2012-02-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.
Nature, 483, 2012
2HII
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BU of 2hii by Molmil
heterotrimeric PCNA sliding clamp
Descriptor: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405)
Authors:Pascal, J.M, Tsodikov, O.V, Ellenberger, T.
Deposit date:2006-06-29
Release date:2006-11-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006
2HIK
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BU of 2hik by Molmil
heterotrimeric PCNA sliding clamp
Descriptor: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405)
Authors:Pascal, J.M, Tsodikov, O.V, Ellenberger, T.
Deposit date:2006-06-29
Release date:2006-11-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006
3GPM
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BU of 3gpm by Molmil
Structure of the trimeric form of the E113G PCNA mutant protein
Descriptor: Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
Deposit date:2009-03-23
Release date:2009-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
Acta Crystallogr.,Sect.D, 65, 2009
5E0T
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BU of 5e0t by Molmil
Human PCNA mutant - S228I
Descriptor: Proliferating cell nuclear antigen
Authors:Duffy, C.M, Hilbert, B.J, Kelch, B.A.
Deposit date:2015-09-29
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6653 Å)
Cite:A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
3HI8
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BU of 3hi8 by Molmil
Crystal structure of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii
Descriptor: Proliferating cell nuclear antigen PcnA
Authors:Morgunova, E, Gray, F.C, MacNeill, S.A, Ladenstein, R.
Deposit date:2009-05-19
Release date:2009-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.202 Å)
Cite:Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment.
Acta Crystallogr.,Sect.D, 65, 2009
2IO4
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BU of 2io4 by Molmil
Crystal structure of PCNA12 dimer from Sulfolobus solfataricus.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, DNA polymerase sliding clamp B, ...
Authors:Hlinkova, V, Ling, H.
Deposit date:2006-10-09
Release date:2008-04-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
3IFV
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BU of 3ifv by Molmil
Crystal structure of the Haloferax volcanii proliferating cell nuclear antigen
Descriptor: PCNA, SODIUM ION
Authors:Winter, J.A, Christofi, P, Morroll, S, Bunting, K.A.
Deposit date:2009-07-26
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation
Bmc Struct.Biol., 9, 2009
5DA7
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BU of 5da7 by Molmil
monomeric PCNA bound to a small protein inhibitor
Descriptor: DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ...
Authors:Ladner, J.E, Altieri, A.S, Kelman, Z.
Deposit date:2015-08-19
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
5E0U
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BU of 5e0u by Molmil
Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
Authors:Duffy, C.M, Hilbert, B.J, Kelch, B.A.
Deposit date:2015-09-29
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
5E0V
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BU of 5e0v by Molmil
Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms
Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen
Authors:Duffy, C.M, Hilbert, B.J, Kelch, B.A.
Deposit date:2015-09-29
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.074 Å)
Cite:A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
6S1M
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BU of 6s1m by Molmil
Human polymerase delta holoenzyme Conformer 1
Descriptor: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
Authors:Lancey, C, Hamdan, S.M, De Biasio, A.
Deposit date:2019-06-19
Release date:2019-12-25
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.27 Å)
Cite:Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
2IJX
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BU of 2ijx by Molmil
Crystal structure of PCNA3 monomer from Sulfolobus solfataricus.
Descriptor: 1,2-ETHANEDIOL, DNA polymerase sliding clamp A
Authors:Hlinkova, V, Ling, H.
Deposit date:2006-10-01
Release date:2007-10-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
2IZO
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BU of 2izo by Molmil
Structure of an Archaeal PCNA1-PCNA2-FEN1 Complex
Descriptor: DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C, FLAP STRUCTURE-SPECIFIC ENDONUCLEASE, ...
Authors:Dore, A.S, Kilkenny, M.L, Roe, S.M, Pearl, L.H.
Deposit date:2006-07-25
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of an Archaeal PCNA1-PCNA2-Fen1 Complex: Elucidating PCNA Subunit and Client Enzyme Specificity.
Nucleic Acids Res., 34, 2006
6S1N
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BU of 6s1n by Molmil
Human polymerase delta holoenzyme Conformer 2
Descriptor: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
Authors:Lancey, C, Hamdan, S.M, De Biasio, A.
Deposit date:2019-06-19
Release date:2019-12-25
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.86 Å)
Cite:Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
2IX2
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BU of 2ix2 by Molmil
Crystal structure of the heterotrimeric PCNA from Sulfolobus solfataricus
Descriptor: DNA POLYMERASE SLIDING CLAMP A, DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C
Authors:Williams, G.J, Johnson, K, McMahon, S.A, Carter, L, Oke, M, Liu, H, Taylor, G.L, White, M.F, Naismith, J.H.
Deposit date:2006-07-05
Release date:2006-10-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Heterotrimeric PCNA from Sulfolobus Solfataricus.
Acta Crystallogr.,Sect.F, 62, 2006
6QC0
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BU of 6qc0 by Molmil
PCNA complex with Cdt2 C-terminal PIP-box peptide
Descriptor: Denticleless protein homolog, Proliferating cell nuclear antigen
Authors:Perrakis, A.P, von Castelmur, E.
Deposit date:2018-12-25
Release date:2019-01-23
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1.
Life Sci Alliance, 1, 2018
6QCG
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BU of 6qcg by Molmil
PCNA complex with Cdt1 N-terminal PIP-box peptide
Descriptor: DNA replication factor Cdt1, Proliferating cell nuclear antigen
Authors:Perrakis, A, von Castelmur, E.
Deposit date:2018-12-28
Release date:2019-01-23
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1.
Life Sci Alliance, 1, 2018
6QH1
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BU of 6qh1 by Molmil
The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide
Descriptor: Proliferating cell nuclear antigen, S-phase delaying protein 1
Authors:Kragelund, B.B, Nielsen, O, Olsen, J.G, Kassem, N, Prestel, A.
Deposit date:2019-01-14
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide
To Be Published
5DAI
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BU of 5dai by Molmil
Proliferating cell nuclear antigen homolog 1 bound to FEN-1 peptide
Descriptor: C-terminus of FEN-1 protein, DNA polymerase sliding clamp 1, SULFATE ION
Authors:Ladner, J.E, Altieri, A.S, Kelman, Z.
Deposit date:2015-08-20
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
6S1O
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BU of 6s1o by Molmil
Human polymerase delta holoenzyme Conformer 3
Descriptor: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
Authors:Lancey, C, Hamdan, S.M, De Biasio, A.
Deposit date:2019-06-19
Release date:2019-12-25
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
3GPN
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BU of 3gpn by Molmil
Structure of the non-trimeric form of the E113G PCNA mutant protein
Descriptor: Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
Deposit date:2009-03-23
Release date:2009-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
Acta Crystallogr.,Sect.D, 65, 2009

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