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4HK1	Crystal Structure of PCNA from Drosophila melanogaster Descriptor: Proliferating cell nuclear antigen Authors: Wang, K, Shi, Z.B, Zhou, Z.C. Deposit date: 2012-10-14 Release date: 2013-04-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Structure of PCNA from Drosophila melanogaster. Acta Crystallogr.,Sect.F, 69, 2013
6E49	Pif1 peptide bound to PCNA trimer Descriptor: ATP-dependent DNA helicase PIF1, Proliferating cell nuclear antigen Authors: Buzovetsky, O, Kwon, Y, Pham, N.T, Kim, C, Ira, G, Sung, P, Xiong, Y. Deposit date: 2018-07-17 Release date: 2018-08-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Role of the Pif1-PCNA Complex in Pol delta-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication. Cell Rep, 21, 2017
6S1M	Human polymerase delta holoenzyme Conformer 1 Descriptor: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... Authors: Lancey, C, Hamdan, S.M, De Biasio, A. Deposit date: 2019-06-19 Release date: 2019-12-25 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (4.27 Å) Cite: Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
3WGW	Structure of PCNA bound to a small molecule inhibitor Descriptor: 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION Authors: Hashimoto, H. Deposit date: 2013-08-12 Release date: 2014-02-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.8 Å) Cite: A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J.Biol.Chem., 289, 2014
7WP3	Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution Descriptor: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, Proliferating cell nuclear antigen Authors: Ahmad, M.I, Yadav, S.P, Singh, P.K, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2022-01-22 Release date: 2022-06-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.954 Å) Cite: Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution To Be Published
7BUP	Crystal structure of PCNA from pathogenic yeast Candida albicans Descriptor: Proliferating cell nuclear antigen Authors: sundaram, R, Vasudevan, D. Deposit date: 2020-04-07 Release date: 2021-02-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural analyses of PCNA from the fungal pathogen Candida albicans identify three regions with species-specific conformations. Febs Lett., 595, 2021
4YHR	Crystal Structure of Yeast Proliferating Cell Nuclear Antigen Descriptor: Proliferating cell nuclear antigen Authors: Litman, J.M, Nguyen, V.Q, Kondratick, C.M, Powers, K.T, Schnieders, M.J, Washington, M.T. Deposit date: 2015-02-27 Release date: 2015-03-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.9502 Å) Cite: Dead-End Elimination with a Polarizable Force Field Repacks PCNA Models from Low-Resolution X-ray Diffraction into Atomic Resolution Structures To be published
1AXC	HUMAN PCNA Descriptor: P21/WAF1, PCNA Authors: Gulbis, J.M, Kuriyan, J. Deposit date: 1997-10-14 Release date: 1998-01-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Cell(Cambridge,Mass.), 87, 1996
4RJF	Crystal structure of the human sliding clamp at 2.0 angstrom resolution Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen Authors: Kroker, A.J, Bruning, J.B. Deposit date: 2014-10-09 Release date: 2015-08-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.0072 Å) Cite: p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding. Biochemistry, 54, 2015
1GE8	PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) HOMOLOG FROM PYROCOCCUS FURIOSUS Descriptor: PROLIFERATION CELL NUCLEAR ANTIGEN Authors: Matsumiya, S, Ishino, Y, Morikawa, K. Deposit date: 2000-10-18 Release date: 2001-01-24 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of an archaeal DNA sliding clamp: proliferating cell nuclear antigen from Pyrococcus furiosus. Protein Sci., 10, 2001
8P9O	PCNA from Chaetomium thermophilum in complex with PolD3 peptide Descriptor: Proliferating cell nuclear antigen, Synthetic peptide corresponding to amino acids 437 to 451 of PolD3 from Chaetomium thermophilum Authors: Alphey, M.S, Wolford, C.B, MacNeill, S.A. Deposit date: 2023-06-06 Release date: 2023-12-13 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Canonical binding of Chaetomium thermophilum DNA polymerase delta / zeta subunit PolD3 and flap endonuclease Fen1 to PCNA. Front Mol Biosci, 10, 2023
6O09	Structure of AtPCNA in complex with the PIP motif of ATXR6 Descriptor: Proliferating cellular nuclear antigen 1, Uncharacterized protein Authors: Couture, J.F, Davarinejad, H. Deposit date: 2019-02-15 Release date: 2019-03-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.06 Å) Cite: ATXR5/6 Forms Alternative Protein Complexes with PCNA and the Nucleosome Core Particle. J. Mol. Biol., 431, 2019
7EFA	Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA Descriptor: Adenine DNA glycosylase, Proliferating cell nuclear antigen Authors: Nakamura, T, Nakabeppu, Y, Yamagata, Y. Deposit date: 2021-03-21 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic Acids Res., 49, 2021
4ZTD	Crystal Structure of Human PCNA in complex with a TRAIP peptide Descriptor: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen Authors: Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A. Deposit date: 2015-05-14 Release date: 2015-12-16 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.199 Å) Cite: TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J.Cell Biol., 212, 2016
3LX2	Crystal Structure analysis of PCNA from Thermococcus kodakaraensis tk0582 Descriptor: DNA polymerase sliding clamp 2, SULFATE ION Authors: Ladner, J.E, Kelman, Z, Pan, M. Deposit date: 2010-02-24 Release date: 2011-01-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc.Natl.Acad.Sci.USA, 108, 2011
3LX1	Crystal Structure analysis of PCNA1 from Thermococcus kodakaraensis tk0535 Descriptor: DNA polymerase sliding clamp 1, SULFATE ION Authors: Ladner, J.E, Kelman, Z, Pan, M. Deposit date: 2010-02-24 Release date: 2011-01-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis. Proc.Natl.Acad.Sci.USA, 108, 2011
5A6D	Proliferating Cell Nuclear Antigen, PCNA, from Thermococcus gammatolerans Descriptor: DNA POLYMERASE SLIDING CLAMP Authors: Venancio-Landeros, A, Cardona-Felix, C.S, Rudino-Pinera, E. Deposit date: 2015-06-25 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans. Biochem Biophys Rep, 8, 2016
4L60	Structure of C81R Mutant PCNA Protein Defective in Mismatch Repair Descriptor: Proliferating cell nuclear antigen Authors: Washington, T, Boehm, E. Deposit date: 2013-06-11 Release date: 2013-10-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.003 Å) Cite: Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair. Biochemistry, 52, 2013
7EP8	Crystal structure of PCNA from Neurospora crassa Descriptor: Proliferating cell nuclear antigen Authors: Sundaram, R, Vasudevan, D. Deposit date: 2021-04-26 Release date: 2021-06-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA. J.Biol.Chem., 297, 2021
4L6P	Structure of C22Y Mutant PCNA protein defective in DNA mismatch repair Descriptor: GLYCEROL, Proliferating cell nuclear antigen Authors: Washington, T, Boehm, E. Deposit date: 2013-06-12 Release date: 2014-10-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair. Biochemistry, 52, 2013
8B8T	Open conformation of the complex of DNA ligase I on PCNA and DNA in the presence of ATP Descriptor: DNA ligase 1, Proliferating cell nuclear antigen Authors: Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A. Deposit date: 2022-10-05 Release date: 2023-01-11 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing. Nat Commun, 13, 2022
5JNE	E2-SUMO-Siz1 E3-SUMO-PCNA complex Descriptor: E3 SUMO-protein ligase SIZ1,Ubiquitin-like protein SMT3, GLYCEROL, Proliferating cell nuclear antigen, ... Authors: Lima, C.D, Streich Jr, F.C. Deposit date: 2016-04-29 Release date: 2016-08-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Capturing a substrate in an activated RING E3/E2-SUMO complex. Nature, 536, 2016
5IY4	Crystal structure of human PCNA in complex with the PIP box of DVC1 Descriptor: DVC1 PIP box, Proliferating cell nuclear antigen Authors: Jiang, T, Xu, M, Wang, Y. Deposit date: 2016-03-24 Release date: 2016-06-08 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.945 Å) Cite: Crystal structure of human PCNA in complex with the PIP box of DVC1 Biochem.Biophys.Res.Commun., 474, 2016
1PLQ	CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA Descriptor: MERCURY (II) ION, PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) Authors: Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J. Deposit date: 1995-01-02 Release date: 1995-03-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. Cell(Cambridge,Mass.), 79, 1994
2OD8	Structure of a peptide derived from Cdc9 bound to PCNA Descriptor: DNA ligase I, mitochondrial precursor, Proliferating cell nuclear antigen Authors: Chapados, B.R, Tainer, J.A. Deposit date: 2006-12-21 Release date: 2007-05-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase. Nucleic Acids Res., 35, 2007

 

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