Crystal structure of the human sliding clamp at 2.0 angstrom resolution

Summary for 4RJF

DescriptorProliferating cell nuclear antigen, Cyclin-dependent kinase inhibitor 1 (3 entities in total)
Functional Keywordssliding clamp, processivity factor, p21, dna polymerase, nucleus, replication
Biological sourceHomo sapiens (human)
Cellular locationNucleus  P12004
Cytoplasm P38936
Total number of polymer chains6
Total molecular weight94676.95
Kroker, A.J.,Bruning, J.B. (deposition date: 2014-10-09, release date: 2015-08-26)
Primary citation
Kroker, A.J.,Bruning, J.B.
p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding.
Biochemistry, 54:3483-3493, 2015
PubMed: 25972089 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.5b00241
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.19580.4%1.0%0.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4rjf
no rotation
Molmil generated image of 4rjf
rotated about x axis by 90°
Molmil generated image of 4rjf
rotated about y axis by 90°
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