4RJF
Crystal structure of the human sliding clamp at 2.0 angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Proliferating cell nuclear antigen | polymer | 261 | 28795.8 | 3 | UniProt (P12004) Pfam (PF00705) Pfam (PF02747) | Homo sapiens (human) | PCNA, Cyclin |
| 2 | B, D, F (B, D, F) | Cyclin-dependent kinase inhibitor 1 | polymer | 22 | 2763.2 | 3 | UniProt (P38936) | Homo sapiens | CDK-interacting protein 1, Melanoma differentiation-associated protein 6, MDA-6, p21 |
| 3 | G, H, I, J, K... (A, B, C, D, E...) | water | water | 18.0 | 1927 | Chemie (HOH) |
Sequence modifications
B, D, F: 139 - 160 (UniProt: P38936)
| PDB | External Database | Details |
|---|---|---|
| Phe 151 | Tyr 151 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 94677.0 | |
| All* | Total formula weight | 94677.0 |
