6WTF
 
 | | Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with tryptophan substrate and SAM analog (aza-SAM) bound | | 分子名称: | COBALAMIN, IRON/SULFUR CLUSTER, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE, ... | | 著者 | Knox, H.L, Chen, P.Y.-T, Drennan, C.L, Booker, S.J. | | 登録日 | 2020-05-02 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Nat.Chem.Biol., 17, 2021
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7KDX
 | | Crystal structure of Streptomyces tokunonesis TokK with hydroxycobalamin, 5'-deoxyadenosine, and methionine | | 分子名称: | 1,2-ETHANEDIOL, 5'-DEOXYADENOSINE, CHLORIDE ION, ... | | 著者 | Knox, H.L, Booker, S.J, Boal, A.K. | | 登録日 | 2020-10-09 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.791 Å) | | 主引用文献 | Structure of a B 12 -dependent radical SAM enzyme in carbapenem biosynthesis.
Nature, 602, 2022
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7KDY
 | | Crystal structure of Streptomyces tokunonesis TokK with hydroxycobalamin, 5'-deoxyadenosine, methionine, and (2R)-pantetheinylated carbapenam | | 分子名称: | (2R,3R,5R)-3-{[2-({N-[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 5'-DEOXYADENOSINE, COBALAMIN, ... | | 著者 | Knox, H.L, Booker, S.J, Boal, A.K. | | 登録日 | 2020-10-09 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.939 Å) | | 主引用文献 | Structure of a B 12 -dependent radical SAM enzyme in carbapenem biosynthesis.
Nature, 602, 2022
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7REQ
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7TE2
 | | Crystal Structure of AerR from Rhodobacter capsulatus at 2.25 A. | | 分子名称: | AerR, CHLORIDE ION, COBALAMIN, ... | | 著者 | Dragnea, V, Gonzalez-Gutierrez, G, Bauer, C.E. | | 登録日 | 2022-01-04 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural Analyses of CrtJ and Its B 12 -Binding Co-Regulators SAerR and LAerR from the Purple Photosynthetic Bacterium Rhodobacter capsulatus.
Microorganisms, 10, 2022
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7XCN
 | | Crystal structure of the MttB-MttC complex at 2.7 A resolution | | 分子名称: | 5-HYDROXYBENZIMIDAZOLYLCOBAMIDE, GLYCEROL, Trimethylamine methyltransferase, ... | | 著者 | Li, J, Chan, M.K. | | 登録日 | 2022-03-24 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex.
Commun Biol, 6, 2023
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8DPB
 | | MeaB in complex with the cobalamin-binding domain of its target mutase with GMPPCP bound | | 分子名称: | GLYCEROL, MAGNESIUM ION, Methylmalonyl-CoA mutase accessory protein, ... | | 著者 | Vaccaro, F.A, Born, D.A, Drennan, C.L. | | 登録日 | 2022-07-15 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Structure of metallochaperone in complex with the cobalamin-binding domain of its target mutase provides insight into cofactor delivery.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8DYJ
 | | Crystal structure of human methylmalonyl-CoA mutase in complex with ADP and cob(II)alamin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, COBALAMIN, Methylmalonyl-CoA mutase, ... | | 著者 | Mascarenhas, R.N, Gouda, H, Banerjee, R. | | 登録日 | 2022-08-04 | | 公開日 | 2023-07-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B 12 repair.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8DYL
 | | Crystal structure of human methylmalonyl-CoA mutase bound to aquocobalamin | | 分子名称: | COBALAMIN, GLYCEROL, Methylmalonyl-CoA mutase, ... | | 著者 | Mascarenhas, R.N, Gouda, H, Banerjee, R. | | 登録日 | 2022-08-04 | | 公開日 | 2023-07-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B 12 repair.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8G3H
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8GJU
 | | Crystal structure of human methylmalonyl-CoA mutase (MMUT) in complex with methylmalonic acidemia type A protein (MMAA), coenzyme A, and GDP | | 分子名称: | COENZYME A, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Mascarenhas, R.M, Ruetz, M, Gouda, H, Yaw, M, Banerjee, R. | | 登録日 | 2023-03-16 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair.
Nat Commun, 14, 2023
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8J2W
 | | Saccharothrix syringae photocobilins protein, dark state | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 5'-DEOXYADENOSINE, BILIVERDINE IX ALPHA, ... | | 著者 | Zhang, S, Poddar, H, Levy, W.C, Leys, D. | | 登録日 | 2023-04-15 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Photocobilins integrate B12 and bilin photochemistry for enzyme control.
Nat Commun, 15, 2024
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8J2X
 | | Saccharothrix syringae photocobilins protein, light state | | 分子名称: | BILIVERDINE IX ALPHA, COBALAMIN, Cobalamin-binding protein, ... | | 著者 | Zhang, S, Poddar, H, Levy, C, Leys, D. | | 登録日 | 2023-04-15 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Photocobilins integrate B12 and bilin photochemistry for enzyme control.
Nat Commun, 15, 2024
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8J2Y
 | | Acidimicrobiaceae bacterium photocobilins protein, dark state | | 分子名称: | 5'-DEOXYADENOSINE, COBALAMIN, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zhang, S, Poddar, H, Levy, W.C, Leys, D. | | 登録日 | 2023-04-15 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Photocobilins integrate B12 and bilin photochemistry for enzyme control.
Nat Commun, 15, 2024
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8SSC
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8SSD
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8SSE
 | | Methionine synthase, C-terminal fragment, Cobalamin and Reactivation Domains from Thermus thermophilus HB8 | | 分子名称: | COBALAMIN, Methionine synthase | | 著者 | Yamada, K, Mendoza, J, Koutmos, M. | | 登録日 | 2023-05-08 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo.
Nat Commun, 14, 2023
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8SSL
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8STA
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