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8SET
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BU of 8set by Molmil
Cryo-EM Structure of RyR1 + cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEO
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BU of 8seo by Molmil
Cryo-EM Structure of RyR1 + ATP-gamma-S
分子名称: Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEX
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BU of 8sex by Molmil
Cryo-EM Structure of RyR1 + AMP (Local Refinement of TMD)
分子名称: ADENOSINE MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SER
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BU of 8ser by Molmil
Cryo-EM Structure of RyR1 + Adenosine
分子名称: ADENOSINE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEU
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BU of 8seu by Molmil
Cryo-EM Structure of RyR1 (Local Refinement of TMD)
分子名称: Ryanodine receptor 1, ZINC ION
著者Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
登録日2023-04-10
公開日2023-05-24
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8DVV
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BU of 8dvv by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2022-07-29
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
To Be Published
8DVE
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BU of 8dve by Molmil
RyR1 in presence of IpCa-T26E phosphomimetic and activating ligands
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Haji-Ghassemi, O, Van Petegm, F.
登録日2022-07-28
公開日2023-05-31
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DUJ
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BU of 8duj by Molmil
Global map in C1 of RyR1 particles in complex with ImperaCalcin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Haji-Ghassemi, O, Van Petegm, F.
登録日2022-07-27
公開日2023-05-31
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DTZ
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BU of 8dtz by Molmil
Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2022-07-26
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published
8DTY
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BU of 8dty by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2022-07-26
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published
8DTB
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BU of 8dtb by Molmil
Focus/local refined map in C1 of signal subtracted RyR1 particles in complex with ImperaCalcin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Imperacalcin, ...
著者Haji-Ghassemi, O, Van Petegm, F.
登録日2022-07-25
公開日2023-05-31
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DRP
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BU of 8drp by Molmil
Focus/local refined map in C4 of signal subtracted RyR1 particles
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Ryanodine receptor 1, ...
著者Haji-Ghassemi, O, Van Petegm, F.
登録日2022-07-21
公開日2023-05-31
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
7UA1
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BU of 7ua1 by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of ARM210
分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7U9T
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BU of 7u9t by Molmil
Structure of PKA phosphorylated human RyR2 in the closed state in the presence of Calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA3
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BU of 7ua3 by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the closed state in the presence of Calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7U9Q
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BU of 7u9q by Molmil
Structure of PKA phosphorylated human RyR2 in the closed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA4
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BU of 7ua4 by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the open state in the presence of Calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7U9X
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BU of 7u9x by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the closed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7U9Z
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BU of 7u9z by Molmil
Structure of PKA phosphorylated human RyR2-R2474S in the open state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7U9R
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BU of 7u9r by Molmil
Structure of PKA phosphorylated human RyR2 in the open state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA5
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BU of 7ua5 by Molmil
Structure of dephosphorylated human RyR2 in the closed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7UA9
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BU of 7ua9 by Molmil
Structure of dephosphorylated human RyR2 in the open state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7TZC
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BU of 7tzc by Molmil
A drug and ATP binding site in type 1 ryanodine receptor
分子名称: (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Melville, Z, Dridi, H, Yuan, Q, Reiken, S, Anetta, W, Liu, Y, Clarke, O.B, Marks, A.R.
登録日2022-02-15
公開日2022-05-18
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献A drug and ATP binding site in type 1 ryanodine receptor.
Structure, 30, 2022
7TDG
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BU of 7tdg by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in inactivated conformation (Dataset-A)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDI
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BU of 7tdi by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 2 (Dataset-A)
分子名称: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022

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件を2024-05-22に公開中

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