PDB: 92 件ウェブページステータス検索Chemie searchBIRD

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3ROF	Crystal Structure of the S. aureus Protein Tyrosine Phosphatase PtpA 分子名称: Expression tag cleaved from protein-tyrosine-phosphatase ptpA, Low molecular weight protein-tyrosine-phosphatase ptpA, PHOSPHATE ION 著者 Grundner, C, Chou, S, Engel, K. 登録日 2011-04-25 公開日 2011-09-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Structure and substrate recognition of the Staphylococcus aureus protein tyrosine phosphatase PtpA. J.Mol.Biol., 413, 2011
4ETN	Crystal structure of YwlE mutant from Bacillus subtilis 分子名称: Low molecular weight protein-tyrosine-phosphatase ywlE, PHOSPHATE ION 著者 Cao, X.F, Su, X.D. 登録日 2012-04-24 公開日 2012-06-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Crystal structure of YwlE mutant from Bacillus subtilis To be published
1JF8	X-ray structure of reduced C10S, C15A arsenate reductase from pI258 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BICARBONATE ION, POTASSIUM ION, ... 著者 Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J. 登録日 2001-06-20 公開日 2001-10-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty. Nat.Struct.Biol., 8, 2001
7DHF	Vibrio vulnificus Wzb in complex with benzylphosphonate 分子名称: GLYCEROL, PHOSPHATE ION, Protein-tyrosine-phosphatase 著者 Ma, Q, Wang, X. 登録日 2020-11-14 公開日 2021-01-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.211 Å) 主引用文献 Wzb of Vibrio vulnificus represents a new group of low-molecular-weight protein tyrosine phosphatases with a unique insertion in the W-loop. J.Biol.Chem., 296, 2021
7KH8	Human LMPTP in complex with inhibitor 分子名称: 3-[(2,6-dichlorophenyl)methyl]-8-(2-methylphenyl)-3H-purin-6-amine, Low molecular weight phosphotyrosine protein phosphatase, NITRATE ION 著者 Stanford, S.M, Diaz, M.A, Ardecky, R.J, Zou, J, Roosild, T, Holmes, Z.J, Hedrick, M.P, Rodiles, S, Santelli, E, Chung, T.D.Y, Jackson, M.R, Bottini, N, Pinkerton, A.B. 登録日 2020-10-20 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine Phosphatase. J.Med.Chem., 64, 2021
1LJU	X-RAY STRUCTURE OF C15A ARSENATE REDUCTASE FROM PI258 COMPLEXED WITH ARSENITE 分子名称: POTASSIUM ION, arsenate reductase 著者 Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J. 登録日 2002-04-22 公開日 2002-08-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc.Natl.Acad.Sci.USA, 99, 2002
4PIC	YwlE arginine phosphatase from Geobacillus stearothermophilus 分子名称: Arginine phosphatase Ywle, PHOSPHATE ION, SULFATE ION 著者 Clausen, T, Fuhrmann, J. 登録日 2014-05-08 公開日 2014-05-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Chasing phosphoarginine proteins: development of a selective enrichment method using a phosphatase trap. Mol.Cell Proteomics, 2014
5KQL	Co-crystal structure of LMW-PTP in complex with 2-oxo-1-phenyl-2-(phenylamino)ethanesulfonic acid 分子名称: (1~{S})-2-oxidanylidene-1-phenyl-2-phenylazanyl-ethanesulfonic acid, Low molecular weight phosphotyrosine protein phosphatase 著者 Wang, J, Zhang, Z.-Y, Yu, Z.-H. 登録日 2016-07-06 公開日 2016-10-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism. J.Med.Chem., 2016
4LRQ	Crystal structure of a Low Molecular Weight Phosphotyrosine phosphatase from Vibrio choleraeO395 分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Phosphotyrosine protein phosphatase, SULFATE ION 著者 Nath, S, Banerjee, R, Sen, U. 登録日 2013-07-20 公開日 2014-07-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Atomic resolution crystal structure of VcLMWPTP-1 from Vibrio cholerae O395: insights into a novel mode of dimerization in the low molecular weight protein tyrosine phosphatase family. Biochem.Biophys.Res.Commun., 450, 2014
5JNT	Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with MES 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... 著者 Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. 登録日 2016-04-30 公開日 2017-03-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. Nat. Chem. Biol., 13, 2017
5KQG	Co-crystal structure of LMW-PTP in complex with 2-(benzothiazol-2-ylamino)-2-oxo-1-phenylethanesulfonic acid 分子名称: (1~{S})-2-(1,3-benzothiazol-2-ylamino)-2-oxidanylidene-1-phenyl-ethanesulfonic acid, Low molecular weight phosphotyrosine protein phosphatase 著者 Wang, J, Zhang, Z.-Y, Yu, Z.-H. 登録日 2016-07-06 公開日 2016-10-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism. J.Med.Chem., 2016
8P5N	Arsenate reductase (ArsC2) from Deinococcus indicus, co-crystallized with arsenate 分子名称: ARSENATE, GLYCEROL, Low molecular weight phosphatase family protein 著者 Gouveia, A.G, Matias, P.M, Romao, C.V. 登録日 2023-05-24 公開日 2023-08-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus . Front Microbiol, 14, 2023
2CD7	Staphylococcus aureus pI258 arsenate reductase (ArsC) H62Q mutant 分子名称: PROTEIN ARSC, SODIUM ION 著者 Buts, L, Roos, G, Van Belle, K, Brosens, E, Loris, R, Wyns, L, Messens, J. 登録日 2006-01-23 公開日 2006-06-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Interplay between Ion Binding and Catalysis in the Thioredoxin-Coupled Arsenate Reductase Family. J.Mol.Biol., 360, 2006
3N8I	Crystal structure of the A isoform of human cytoplasmic protein tyrosine phosphatase (HCPTP-A) in complex with 1-naphtylacetic acid 分子名称: Low molecular weight phosphotyrosine protein phosphatase, NAPHTHALEN-1-YL-ACETIC ACID 著者 Homan, K.T, Balasubramaniam, D, Stauffacher, C.V. 登録日 2010-05-28 公開日 2011-12-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Characterization of a Secondary Binding Site on Low Molecular Weight Protein Tyrosine Phosphatases To be Published
7UW6	The co-crystal structure of low molecular weight protein tyrosine phosphatase (LMW-PTP) with a small molecule inhibitor SPAA-2 分子名称: 2-[(1,3-benzothiazol-2-yl)amino]-2-oxoethane-1-sulfonic acid, Low molecular weight phosphotyrosine protein phosphatase 著者 Wang, J, Zhang, Z.Y. 登録日 2022-05-02 公開日 2022-10-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. J.Med.Chem., 65, 2022
1RXI	pI258 arsenate reductase (ArsC) triple mutant C10S/C15A/C82S 分子名称: Arsenate reductase, CHLORIDE ION, PERCHLORATE ION, ... 著者 Messens, J, Van Molle, I, Vanhaesebrouck, P, Limbourg, M, Van Belle, K, Wahni, K, Martins, J.C, Loris, R, Wyns, L. 登録日 2003-12-18 公開日 2004-06-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct. Acta Crystallogr.,Sect.D, 60, 2004
4D74	1.57 A crystal structure of erwinia amylovora tyrosine phosphatase amsI 分子名称: PROTEIN-TYROSINE-PHOSPHATASE AMSI, SULFATE ION 著者 Benini, S, Salomone-Stagni, M, Caputi, L, Cianci, M. 登録日 2014-11-19 公開日 2016-01-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Characterization and 1.57 A Resolution Structure of the Key Fire Blight Phosphatase Amsi from Erwinia Amylovora Acta Crystallogr.,Sect.F, 72, 2016
5JNV	Crystal structure of bovine low molecular weight protein tyrosine phosphatase (LMPTP) mutant (W49Y N50E) complexed with HEPES 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Low molecular weight phosphotyrosine protein phosphatase 著者 Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. 登録日 2016-04-30 公開日 2017-03-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. Nat. Chem. Biol., 13, 2017
1JL3	Crystal Structure of B. subtilis ArsC 分子名称: ARSENATE REDUCTASE, SULFATE ION 著者 Su, X.-D, Bennett, M.S. 登録日 2001-07-15 公開日 2001-10-24 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Bacillus subtilis arsenate reductase is structurally and functionally similar to low molecular weight protein tyrosine phosphatases. Proc.Natl.Acad.Sci.USA, 98, 2001
1LK0	Disulfide intermediate of C89L Arsenate reductase from pI258 分子名称: CHLORIDE ION, POTASSIUM ION, arsenate reductase 著者 Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. 登録日 2002-04-23 公開日 2002-08-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc.Natl.Acad.Sci.USA, 99, 2002
4ETM	Crystal structure of YfkJ from Bacillus subtilis 分子名称: Low molecular weight protein-tyrosine-phosphatase yfkJ, PHOSPHATE ION, POTASSIUM ION, ... 著者 Cao, X.F, Su, X.D. 登録日 2012-04-24 公開日 2012-10-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of YfkJ from Bacillus subtilis To be published
1XWW	Crystal Structure of Human B-form Low Molecular Weight Phosphotyrosyl Phosphatase at 1.6 Angstrom Resolution 分子名称: GLYCEROL, Low molecular weight phosphotyrosine protein phosphatase, SULFATE ION 著者 Stauffacher, C.V, Zabell, A.P.R. 登録日 2004-11-02 公開日 2005-11-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Crystal structure of the human B-form low molecular weight phosphotyrosyl phosphatase at 1.6-A resolution. J.Biol.Chem., 281, 2006
8P6M	Arsenate reductase (ArsC2) from Deinococcus indicus 分子名称: Low molecular weight phosphatase family protein 著者 Gouveia, A.G, Matias, P.M, Romao, C.V. 登録日 2023-05-26 公開日 2023-08-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus . Front Microbiol, 14, 2023
4KK3	YwlE arginine phosphatase - wildtype 分子名称: Low molecular weight protein-tyrosine-phosphatase YwlE, PHOSPHATE ION 著者 Fuhrmann, J, Clausen, T. 登録日 2013-05-05 公開日 2013-07-03 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep, 3, 2013
1RXE	ArsC complexed with MNB 分子名称: 5-MERCAPTO-2-NITRO-BENZOIC ACID, Arsenate reductase, PERCHLORATE ION, ... 著者 Messens, J, Van Molle, I, Vanhaesebrouck, P, Limbourg, M, Van Belle, K, Wahni, K, Martins, J.C, Loris, R, Wyns, L. 登録日 2003-12-18 公開日 2004-06-01 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct. Acta Crystallogr.,Sect.D, 60, 2004

 

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