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5JNT

Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with MES

Summary for 5JNT
Entry DOI10.2210/pdb5jnt/pdb
Related5JNR 5JNS 5JNU 5JNV 5JNW
DescriptorLow molecular weight phosphotyrosine protein phosphatase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywordsprotein tyrosine phosphatase, hydrolase, lmw-ptp, lmptp
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight18635.19
Authors
Stanford, S.M.,Aleshin, A.E.,Liddington, R.C.,Bankston, L.,Cadwell, G.,Bottini, N. (deposition date: 2016-04-30, release date: 2017-03-29, Last modification date: 2023-09-27)
Primary citationStanford, S.M.,Aleshin, A.E.,Zhang, V.,Ardecky, R.J.,Hedrick, M.P.,Zou, J.,Ganji, S.R.,Bliss, M.R.,Yamamoto, F.,Bobkov, A.A.,Kiselar, J.,Liu, Y.,Cadwell, G.W.,Khare, S.,Yu, J.,Barquilla, A.,Chung, T.D.Y.,Mustelin, T.,Schenk, S.,Bankston, L.A.,Liddington, R.C.,Pinkerton, A.B.,Bottini, N.
Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13:624-632, 2017
Cited by
PubMed: 28346406
DOI: 10.1038/nchembio.2344
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.45 Å)
Structure validation

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