6FVE
 
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3GAD
 | | Structure of apomif | | Descriptor: | ACETIC ACID, Macrophage migration inhibitory factor-like protein, SULFATE ION | | Authors: | Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. | | Deposit date: | 2009-02-17 | | Release date: | 2009-12-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host
Mol.Immunol., 47, 2010
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3GAC
 | | Structure of mif with HPP | | Descriptor: | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ACETIC ACID, Macrophage migration inhibitory factor-like protein, ... | | Authors: | Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. | | Deposit date: | 2009-02-17 | | Release date: | 2009-12-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host
Mol.Immunol., 47, 2010
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3HOF
 | | Structure of macrophage migration inhibitory factor (MIF) with caffeic acid at 1.9A resolution | | Descriptor: | CAFFEIC ACID, Macrophage migration inhibitory factor | | Authors: | Crawley, L, Barker, J, Cheng, R.K.Y, Wood, M, Felicetti, B. | | Deposit date: | 2009-06-02 | | Release date: | 2009-06-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of macrophage migration inhibitory factor (MIF) with caffeic acid at 1.9A resolution
To be Published
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4Z1T
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4Z15
 | | MIF in complex with 3-(2-furylmethyl)-2-thioxo-1,3-thiazolan-4-one | | Descriptor: | ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION | | Authors: | Cho, T.Y. | | Deposit date: | 2015-03-26 | | Release date: | 2016-09-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors.
J. Cell. Mol. Med., 21, 2017
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4Z1U
 | | MIF in complex with 1-(4-methylphenyl)-3-phenylprop-2-yn-1-one | | Descriptor: | GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION | | Authors: | Cho, T.Y. | | Deposit date: | 2015-03-27 | | Release date: | 2016-09-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors.
J. Cell. Mol. Med., 21, 2017
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5BS9
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5B4O
 | | Crystal structure of Macrophage Migration Inhibitory Factor in complex with BTZO-14 | | Descriptor: | 1,2-ETHANEDIOL, 2-pyridin-3-yl-1,3-benzothiazin-4-one, Macrophage migration inhibitory factor, ... | | Authors: | Oki, H, Igaki, S, Moriya, Y, Hayano, Y, Habuka, N. | | Deposit date: | 2016-04-07 | | Release date: | 2016-04-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression
Chem. Biol., 17, 2010
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5BSJ
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5BSC
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5BSI
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4DH4
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4EUI
 | | Crystal Structure of MIF L46F mutant | | Descriptor: | Macrophage migration inhibitory factor, SULFATE ION | | Authors: | Ashrafi, A, Pojer, F, Lashuel, H. | | Deposit date: | 2012-04-25 | | Release date: | 2012-10-03 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: leucine 46 hydrophobic pocket.
Plos One, 7, 2012
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4ETG
 | | Crystal Structure of MIF L46G mutant | | Descriptor: | Macrophage migration inhibitory factor, SULFATE ION | | Authors: | Ashrafi, A, Pojer, F, Lashuel, H. | | Deposit date: | 2012-04-24 | | Release date: | 2012-10-03 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: leucine 46 hydrophobic pocket.
Plos One, 7, 2012
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4EVG
 | | Crystal Structure of MIF L46A mutant | | Descriptor: | Macrophage migration inhibitory factor, SULFATE ION | | Authors: | Ashrafi, A, Pojer, F, Lashuel, H. | | Deposit date: | 2012-04-26 | | Release date: | 2012-10-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: leucine 46 hydrophobic pocket.
Plos One, 7, 2012
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4F2K
 | | Macrophage Migration Inhibitory Factor covalently complexed with phenethylisothiocyanate | | Descriptor: | ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, N-(2-phenylethyl)thioformamide, ... | | Authors: | Tyndall, J.D.A, Bernhagen, J, Hampton, M.B, Wilbanks, S.M, Rutledge, M.T. | | Deposit date: | 2012-05-08 | | Release date: | 2012-06-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Macrophage migration inhibitory factor covalently complexed with phenethyl isothiocyanate
Acta Crystallogr.,Sect.F, 68, 2012
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4GRR
 | | characterization of N- and C- terminus mutants of human MIF | | Descriptor: | (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor, ... | | Authors: | Fan, C, Lolis, E. | | Deposit date: | 2012-08-26 | | Release date: | 2013-09-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | Characterization of N- and C- terminus mutants of human MIF
To be Published
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4GUM
 | | Cystal structure of locked-trimer of human MIF | | Descriptor: | CHLORIDE ION, Macrophage migration inhibitory factor | | Authors: | Fan, C, Lolis, E. | | Deposit date: | 2012-08-29 | | Release date: | 2013-07-03 | | Last modified: | 2020-11-18 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4GRU
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4GRQ
 | | Characterization of N- and C- terminus mutants of human MIF | | Descriptor: | 2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor, ... | | Authors: | Fan, C, Lolis, E. | | Deposit date: | 2012-08-26 | | Release date: | 2013-10-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Characterization of N- and C- terminus mutants of human MIF
To be Published
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4GRO
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8UR4
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8VFK
 | | Crystal Structure of Delta 109-117 D-Dopachrome Tautomerase (D-DT) | | Descriptor: | CITRATE ANION, D-dopachrome decarboxylase, SODIUM ION | | Authors: | Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. | | Deposit date: | 2023-12-21 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes.
J.Med.Chem., 2024
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8VG8
 | | Crystal Structure of T115A Variant of D-Dopachrome Tautomerase (D-DT) Bound to 4CPPC | | Descriptor: | 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid, D-dopachrome decarboxylase | | Authors: | Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. | | Deposit date: | 2023-12-23 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes.
J.Med.Chem., 2024
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