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8B8H
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Structure of DCS-resistant variant D322N of alanine racemase from M. tuberculosis in complex with DCS
分子名称: (~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylidene-[(4~{R})-3-oxidanylidene-1,2-oxazolidin-4-yl]azanium, 1,2-ETHANEDIOL, Alanine racemase, ...
著者de Chiara, C, Prosser, G, Ogrodowicz, R.W, de Carvalho, L.P.S.
登録日2022-10-04
公開日2023-04-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis .
Acs Bio Med Chem Au, 3, 2023
1XQL
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Effect of a Y265F Mutant on the Transamination Based Cycloserine Inactivation of Alanine Racemase
分子名称: (5-HYDROXY-4-{[(3-HYDROXYISOXAZOL-4-YL)AMINO]METHYL}-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ...
著者Fenn, T.D, Holyoak, T, Stamper, G.F, Ringe, D.
登録日2004-10-12
公開日2005-01-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Effect of a Y265F Mutant on the Transamination-Based Cycloserine Inactivation of Alanine Racemase
Biochemistry, 44, 2005
4PB4
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D-threo-3-hydroxyaspartate dehydratase H351A mutant complexed with 2-amino maleic acid
分子名称: 2-amino maleic acid, D-threo-3-hydroxyaspartate dehydratase, MAGNESIUM ION, ...
著者Yasutake, Y, Matsumoto, Y, Wada, M.
登録日2014-04-11
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the substrate stereospecificity of D-threo-3-hydroxyaspartate dehydratase from Delftia sp. HT23: a useful enzyme for the synthesis of optically pure L-threo- and D-erythro-3-hydroxyaspartate.
Appl.Microbiol.Biotechnol., 99, 2015
5YYC
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BU of 5yyc by Molmil
Crystal structure of alanine racemase from Bacillus pseudofirmus (OF4)
分子名称: Alanine racemase, PYRIDOXAL-5'-PHOSPHATE
著者Dong, H, Hu, T.T, He, G.Z, Lu, D.R, Qi, J.X, Dou, Y.S, Long, W, He, X, Su, D, Ju, J.S.
登録日2017-12-08
公開日2019-01-02
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structural features and kinetic characterization of alanine racemase from Bacillus pseudofirmus OF4.
Biochem. Biophys. Res. Commun., 497, 2018
7YQA
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Crystal structure of D-threonine aldolase from Chlamydomonas reinhardtii
分子名称: D-threonine aldolase, MAGNESIUM ION
著者Hirato, Y, Goto, M, Mizobuchi, T, Muramatsu, H, Tanigawa, M, Nishimura, K.
登録日2022-08-05
公開日2023-02-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of pyridoxal 5'-phosphate-bound D-threonine aldolase from Chlamydomonas reinhardtii.
Acta Crystallogr.,Sect.F, 79, 2023
1VFS
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BU of 1vfs by Molmil
Crystal structure of D-cycloserine-bound form of alanine racemase from D-cycloserine-producing Streptomyces lavendulae
分子名称: CHLORIDE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, alanine racemase
著者Noda, M, Matoba, Y, Kumagai, T, Sugiyama, M.
登録日2004-04-19
公開日2004-09-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.
J.Biol.Chem., 279, 2004
6G58
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Structure of the alanine racemase from Staphylococcus aureus in complex with a pyridoxal 5' phosphate-derivative
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, (6-but-3-ynyl-4-methyl-5-oxidanyl-pyridin-3-yl)methyl dihydrogen phosphate, ...
著者Hoegl, A, Sieber, S.A, Schneider, S.
登録日2018-03-29
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics.
Nat Chem, 10, 2018
5NLC
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Structure of PipY, the COG0325 family member of Synechococcus elongatus PCC7942,without PLP
分子名称: PHOSPHATE ION, PipY
著者Tremino, L, Forcada-Nadal, A, Contreras, A, Rubio, V.
登録日2017-04-04
公開日2017-09-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Studies on cyanobacterial protein PipY shed light on structure, potential functions, and vitamin B6 -dependent epilepsy.
FEBS Lett., 591, 2017
4WR3
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Y274F alanine racemase from E. coli
分子名称: Alanine racemase, biosynthetic, GLYCEROL, ...
著者Squire, C.J, Yosaatmadja, Y, Patrick, W.M.
登録日2014-10-23
公開日2015-11-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes.
J.Biol.Chem., 291, 2016
1XFC
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The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site
分子名称: Alanine racemase, PYRIDOXAL-5'-PHOSPHATE
著者LeMagueres, P, Im, H, Ebalunode, J, Strych, U, Benedik, M.J, Briggs, J.M, Kohn, H, Krause, K.L.
登録日2004-09-14
公開日2005-08-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site.
Biochemistry, 44, 2005
4PB5
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BU of 4pb5 by Molmil
D-threo-3-hydroxyaspartate dehydratase H351A mutant complexed with L-erythro-3-hydroxyaspartate
分子名称: (3R)-3-hydroxy-L-aspartic acid, D-threo-3-hydroxyaspartate dehydratase, GLYCEROL, ...
著者Yasutake, Y, Matsumoto, Y, Wada, M.
登録日2014-04-11
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the substrate stereospecificity of D-threo-3-hydroxyaspartate dehydratase from Delftia sp. HT23: a useful enzyme for the synthesis of optically pure L-threo- and D-erythro-3-hydroxyaspartate.
Appl.Microbiol.Biotechnol., 99, 2015
3R79
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Crystal structure of an uncharactertized protein from Agrobacterium tumefaciens
分子名称: ACETATE ION, PRASEODYMIUM ION, PYRIDOXAL-5'-PHOSPHATE, ...
著者Eswaramoorthy, S, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC)
登録日2011-03-22
公開日2011-04-06
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an uncharactertized protein from Agrobacterium tumefaciens
To be Published
2SFP
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ALANINE RACEMASE WITH BOUND PROPIONATE INHIBITOR
分子名称: PROPANOIC ACID, PROTEIN (ALANINE RACEMASE), PYRIDOXAL-5'-PHOSPHATE
著者Morollo, A.A, Petsko, G.A, Ringe, D.
登録日1999-02-16
公開日1999-02-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase.
Biochemistry, 38, 1999
1SFT
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ALANINE RACEMASE
分子名称: ACETATE ION, ALANINE RACEMASE, PYRIDOXAL-5'-PHOSPHATE
著者Shaw, J.P, Petsko, G.A, Ringe, D.
登録日1996-09-20
公開日1997-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-A resolution.
Biochemistry, 36, 1997
4QHR
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The structure of alanine racemase from Acinetobacter baumannii
分子名称: Alanine racemase
著者Davis, E, Scaletti-Hutchinson, E, Nakatani, Y, Krause, K.L.
登録日2014-05-29
公開日2015-05-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of alanine racemase from Acinetobacter baumannii
ACTA CRYSTALLOGR.,SECT.F, 70, 2014
3ANU
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BU of 3anu by Molmil
Crystal structure of D-serine dehydratase from chicken kidney
分子名称: CHLORIDE ION, D-serine dehydratase, PYRIDOXAL-5'-PHOSPHATE, ...
著者Tanaka, H, Senda, M, Venugopalan, N, Yamamoto, A, Senda, T, Ishida, T, Horiike, K.
登録日2010-09-09
公開日2011-06-15
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney
J.Biol.Chem., 286, 2011
6Q71
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Crystal structure of the alanine racemase Bsu17640 from Bacillus subtilis in the presence of Bis-Tris propane
分子名称: Alanine racemase 2, CHLORIDE ION, MAGNESIUM ION, ...
著者Bernardo-Garcia, N, Gago, F, Hermoso, J.A.
登録日2018-12-12
公開日2019-04-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Cold-induced aldimine bond cleavage by Tris in Bacillus subtilis alanine racemase.
Org.Biomol.Chem., 17, 2019
5NM8
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Structure of PipY, the COG0325 family member of Synechococcus elongatus PCC7942, with PLP bound
分子名称: CALCIUM ION, PYRIDOXAL-5'-PHOSPHATE, PipY
著者Tremino, L, Forcada-Nadal, A, Contreras, A, Rubio, V.
登録日2017-04-05
公開日2017-09-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Studies on cyanobacterial protein PipY shed light on structure, potential functions, and vitamin B6 -dependent epilepsy.
FEBS Lett., 591, 2017
1XQK
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BU of 1xqk by Molmil
Effect of a Y265F Mutant on the Transamination Based Cycloserine Inactivation of Alanine Racemase
分子名称: (5-HYDROXY-4-{[(3-HYDROXYISOXAZOL-4-YL)AMINO]METHYL}-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Alanine racemase
著者Fenn, T.D, Holyoak, T, Stamper, G.F, Ringe, D.
登録日2004-10-12
公開日2005-01-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Effect of a Y265F Mutant on the Transamination-Based Cycloserine Inactivation of Alanine Racemase
Biochemistry, 44, 2005
3HA1
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Alanine racemase from Bacillus Anthracis (Ames)
分子名称: ACETATE ION, Alanine racemase, CHLORIDE ION
著者Counago, R.M, Davlieva, M, Strych, U, Hill, R.E, Krause, K.L.
登録日2009-04-30
公開日2009-09-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames).
Bmc Struct.Biol., 9, 2009
1VFH
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Crystal structure of alanine racemase from D-cycloserine producing Streptomyces lavendulae
分子名称: PYRIDOXAL-5'-PHOSPHATE, alanine racemase
著者Noda, M, Matoba, Y, Kumagai, T, Sugiyama, M.
登録日2004-04-13
公開日2004-09-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.
J.Biol.Chem., 279, 2004
1W8G
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CRYSTAL STRUCTURE OF E. COLI K-12 YGGS
分子名称: HYPOTHETICAL UPF0001 PROTEIN YGGS, ISOCITRIC ACID, PYRIDOXAL-5'-PHOSPHATE
著者Sulzenbacher, G, Gruez, A, Spinelli, S, Roig-Zamboni, V, Pagot, F, Bignon, C, Vincentelli, R, Cambillau, C.
登録日2004-09-21
公開日2006-07-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of E. Coli K-12 Yggs
To be Published
1L6G
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Alanine racemase bound with N-(5'-phosphopyridoxyl)-D-alanine
分子名称: N-(5'-PHOSPHOPYRIDOXYL)-D-ALANINE, alanine racemase
著者Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N.
登録日2002-03-10
公開日2002-06-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J.Biol.Chem., 277, 2002
1L6F
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Alanine racemase bound with N-(5'-phosphopyridoxyl)-L-alanine
分子名称: ALANYL-PYRIDOXAL-5'-PHOSPHATE, alanine racemase
著者Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N.
登録日2002-03-09
公開日2002-06-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J.Biol.Chem., 277, 2002
7U9H
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Crystal Structure of Escherichia coli apo Pyridoxal 5'-phosphate homeostasis protein (YGGS)
分子名称: Pyridoxal phosphate homeostasis protein, SULFATE ION
著者Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K.
登録日2022-03-10
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022

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