Structure of the alanine racemase from Staphylococcus aureus in complex with a pyridoxal 5' phosphate-derivative

Summary for 6G58

DescriptorAlanine racemase 1, (6-but-3-ynyl-4-methyl-5-oxidanyl-pyridin-3-yl)methyl dihydrogen phosphate, SODIUM ION, ... (9 entities in total)
Functional Keywordspyridoxal 5 phosphate dependent, d-alanine biosynthesis, biosynthetic protein
Biological sourceStaphylococcus aureus
Total number of polymer chains2
Total molecular weight92797.33
Hoegl, A.,Sieber, S.A.,Schneider, S. (deposition date: 2018-03-29, release date: 2018-05-30, Last modification date: 2018-12-05)
Primary citation
Hoegl, A.,Nodwell, M.B.,Kirsch, V.C.,Bach, N.C.,Pfanzelt, M.,Stahl, M.,Schneider, S.,Sieber, S.A.
Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics.
Nat Chem, 10:1234-1245, 2018
PubMed: 30297752 (PDB entries with the same primary citation)
DOI: 10.1038/s41557-018-0144-2
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.18210 0.8% 1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6g58
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Molmil generated image of 6g58
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Molmil generated image of 6g58
rotated about y axis by 90°
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