PDB: 149 件ウェブページステータス検索Chemie searchBIRD

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5X2X	Crystal structure of Pseudomonas putida methionine gamma-lyase wild type with L-homocysteine intermediates 分子名称: (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid, HYDROSULFURIC ACID, L-methionine gamma-lyase 著者 Shiba, T, Sato, D, Harada, S. 登録日 2017-02-02 公開日 2017-04-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and mechanistic insights into homocysteine degradation by a mutant of methionine gamma-lyase based on substrate-assisted catalysis Protein Sci., 26, 2017
5X2W	Crystal structure of Pseudomonas putida methionine gamma-lyase wild type with L-methionine intermediates 分子名称: (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-4-(methylsulfanyl)but-2-enoic acid, L-methionine gamma-lyase 著者 Shiba, T, Sato, D, Harada, S. 登録日 2017-02-02 公開日 2017-04-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and mechanistic insights into homocysteine degradation by a mutant of methionine gamma-lyase based on substrate-assisted catalysis Protein Sci., 26, 2017
5X2V	Crystal structure of Pseudomonas putida methionine gamma-lyase wild type without sulfate ion 分子名称: L-methionine gamma-lyase 著者 Shiba, T, Sato, D, Harada, S. 登録日 2017-02-02 公開日 2017-04-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and mechanistic insights into homocysteine degradation by a mutant of methionine gamma-lyase based on substrate-assisted catalysis Protein Sci., 26, 2017
5TT2	Inactive conformation of engineered human cystathionine gamma lyase (E59N, R119L, E339V) to depleting methionine 分子名称: Cystathionine gamma-lyase, SULFATE ION 著者 Yan, W, Zhang, Y. 登録日 2016-10-31 公開日 2017-10-11 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (2.949 Å) 主引用文献 Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site. Biochemistry, 56, 2017
5TSU	Active conformation for Engineered human cystathionine gamma lyase (E59N, R119L, E339V) to depleting methionine 分子名称: CYSTEINE, Cystathionine gamma-lyase, METHIONINE, ... 著者 Yan, W, Zhang, Y. 登録日 2016-10-31 公開日 2017-10-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site. Biochemistry, 56, 2017
5M3Z	Crystal structure of Citrobacter freundii methionine gamma-lyase with C115H replacement in the complex with L-norleucine 分子名称: 2-[O-PHOSPHONOPYRIDOXYL]-AMINO-HEXANOIC ACID, Methionine gamma-lyase, NORLEUCINE, ... 著者 Revtovich, S.V, Nikulin, A.D, Anufrieva, N.V, Morozova, E.A, Demidkina, T.V. 登録日 2016-10-17 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of mutant form Cys115His of Citrobacter freundii methionine gamma-lyase complexed with l-norleucine. Biochim. Biophys. Acta, 1865, 2017
5K30	Crystal structure of methionine gamma-lyase from Citrobacter freundii modified by S-Ethyl-L-cysteine sulfoxide 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, ... 著者 Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V. 登録日 2016-05-19 公開日 2017-07-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Sulfoxides of sulfur-containing amino acids are suicide substrates of Citrobacter freundii methionine gamma-lyase. Structural bases of the enzyme inactivation. Biochimie, 168, 2020
5IJG	Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution 分子名称: Cys/Met metabolism pyridoxal-phosphate-dependent enzyme, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE 著者 Boyko, K.M, Nikolaeva, A.Y, Koolikova, V.V, Kotlov, M.I, Demidkina, T.V, Popov, V.O. 登録日 2016-03-02 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution To Be Published
5EIG	Engineered human cystathionine gamma lyase (E59T, E339V) to deplet cysteine 分子名称: CYSTEINE, Cystathionine gamma-lyase, SULFATE ION 著者 Yan, W, Zhang, J. 登録日 2015-10-29 公開日 2016-11-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Systemic Depletion of Serum L-Cyst(e)ine with an Engineered Human Enzyme Mediates Potent Induction of ROS and Cancer Ablation To Be Published
5E4Z	Crystal structure of methionine gamma-lyase from Citrobacter freundii with C115A substitution 分子名称: DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, PENTAETHYLENE GLYCOL, ... 著者 Revtovich, S.V, Nikulin, A.D, Anufrieva, N.V, Morozova, E.A, Demidkina, T.V. 登録日 2015-10-07 公開日 2016-10-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Crystal structure of C115A mutant L-methionine gamma-lyase from Citrobacter freundii To Be Published
5DX5	Crystal structure of methionine gamma-lyase from Clostridium sporogenes 分子名称: CHLORIDE ION, Methionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Anufrieva, N.V, Demidkina, T.V. 登録日 2015-09-23 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structure of methionine gamma-lyase from Clostridium sporogenes. Acta Crystallogr.,Sect.F, 72, 2016
5D5S	Crystal structure of methionine gamma-lyase from Citrobacter freundii, S339A mutant 分子名称: DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Revtovich, S.V, Nikulin, A.D, Anufrieva, N.V, Morozova, E.A, Demidkina, T.V. 登録日 2015-08-11 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The crystal structure of methionine gamma-lyase from Citrobacter freundii, S339A mutant To Be Published
4XQ2	Ensemble refinement of cystathione gamma lyase (CalE6) D7G from Micromonospora echinospora 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, CalE6, ... 著者 Wang, F, Yennamalli, R.M, Singh, S, Tan, K, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2015-01-18 公開日 2015-04-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora To Be Published
4U2H	The crystal structure of apo CalE6, a methionine gamma lyase from Micromonospora echinospora 分子名称: CalE6, SULFATE ION 著者 Song, H.G, Xu, R. 登録日 2014-07-17 公開日 2015-01-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Identification and Characterization of a Methionine gamma-Lyase in the Calicheamicin Biosynthetic Cluster of Micromonospora echinospora Chembiochem, 16, 2015
4U1T	The crystal structure of holo CalE6, a methionine gamma lyase from Micromonospora echinospora 分子名称: CalE6, SULFATE ION 著者 Song, H.G, Guo, Z.H. 登録日 2014-07-16 公開日 2015-01-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Identification and Characterization of a Methionine gamma-Lyase in the Calicheamicin Biosynthetic Cluster of Micromonospora echinospora Chembiochem, 16, 2015
4Q31	The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FORMIC ACID, ... 著者 Tan, K, Bigelow, L, Jedrzejczak, R, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2014-04-10 公開日 2014-05-07 最終更新日 2017-03-08 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate. Struct Dyn, 3, 2016
4OMA	The crystal structure of methionine gamma-lyase from Citrobacter freundii in complex with L-cycloserine pyridoxal-5'-phosphate 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ... 著者 Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V. 登録日 2014-01-27 公開日 2014-11-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Pre-steady-state Kinetic and Structural Analysis of Interaction of Methionine gamma-Lyase from Citrobacter freundii with Inhibitors. J.Biol.Chem., 290, 2015
4OC9	2.35 Angstrom resolution crystal structure of putative O-acetylhomoserine (thiol)-lyase (metY) from Campylobacter jejuni subsp. jejuni NCTC 11168 with N'-Pyridoxyl-Lysine-5'-Monophosphate at position 205 分子名称: GLYCEROL, IMIDAZOLE, PHOSPHATE ION, ... 著者 Halavaty, A.S, Brunzelle, J.S, Wawrzak, Z, Onopriyenko, O, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2014-01-08 公開日 2014-03-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 2.35 Angstrom resolution crystal structure of putative O-acetylhomoserine (thiol)-lyase (metY) from Campylobacter jejuni subsp. jejuni NCTC 11168 with N'-Pyridoxyl-Lysine-5'-Monophosphate at position 205 To be Published
4MKK	Crystal structure of C115A mutant L-methionine gamma-lyase from Citrobacter freundii modified by allicine 分子名称: CHLORIDE ION, Methionine gamma-lyase, POTASSIUM ION, ... 著者 Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Zakomirdina, L.N, Demidkina, T.V. 登録日 2013-09-05 公開日 2014-11-12 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Alliin is a suicide substrate of Citrobacter freundii methionine gamma-lyase: structural bases of inactivation of the enzyme. Acta Crystallogr.,Sect.D, 70, 2014
4MKJ	Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine 分子名称: Methionine gamma-lyase, PENTAETHYLENE GLYCOL, SODIUM ION, ... 著者 Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Zakomirdina, L.N, Demidkina, T.V. 登録日 2013-09-05 公開日 2014-11-12 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Alliin is a suicide substrate of Citrobacter freundii methionine gamma-lyase: structural bases of inactivation of the enzyme. Acta Crystallogr.,Sect.D, 70, 2014
4L0O	Structure determination of cystathionine gamma-synthase from Helicobacter pylori 分子名称: Cystathionine gamma-synthase, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE 著者 Tarique, K.F, Rehman, S.A.A, Gourinath, S. 登録日 2013-05-31 公開日 2013-12-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structure determination of cystathionine gamma-synthase from Helicobacter pylori To be Published
4KAM	X-ray crystal structure of O-acetylhomoserine sulfhydrylase MetC from Mycobacterium marinum ATCC BAA-535 / M 分子名称: O-acetylhomoserine sulfhydrylase MetC, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-04-22 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4IYO	Crystal structure of cystathionine gamma lyase from Xanthomonas oryzae pv. oryzae (XometC) in complex with E-site serine, A-site serine, A-site external aldimine structure with aminoacrylate and A-site iminopropionate intermediates 分子名称: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, AMINO-ACRYLATE, Cystathionine gamma-lyase-like protein, ... 著者 Ngo, H.P.T, Kim, J.K, Kang, L.W. 登録日 2013-01-29 公開日 2014-01-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 PLP undergoes conformational changes during the course of an enzymatic reaction. Acta Crystallogr.,Sect.D, 70, 2014
4IY7	crystal structure of cystathionine gamma lyase (XometC) from Xanthomonas oryzae pv. oryzae in complex with E-site serine, A-site external aldimine structure with serine and A-site external aldimine structure with aminoacrylate intermediates 分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Cystathionine gamma-lyase-like protein, ... 著者 Ngo, H.P.T, Kim, J.K, Kang, L.W. 登録日 2013-01-28 公開日 2014-01-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 PLP undergoes conformational changes during the course of an enzymatic reaction. Acta Crystallogr.,Sect.D, 70, 2014
4IXZ	Native structure of cystathionine gamma lyase (XometC) from xanthomonas oryzae pv. oryzae at pH 9.0 分子名称: BETA-MERCAPTOETHANOL, BICARBONATE ION, Cystathionine gamma-lyase-like protein, ... 著者 Ngo, H.P.T, Kim, J.K, Kang, L.W. 登録日 2013-01-28 公開日 2014-01-29 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 PLP undergoes conformational changes during the course of an enzymatic reaction. Acta Crystallogr.,Sect.D, 70, 2014

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