The crystal structure of methionine gamma-lyase from Citrobacter freundii in complex with L-cycloserine pyridoxal-5'-phosphate

Summary for 4OMA

Related2RFV 4HF8 2DAA 1D7U
Descriptormethionine gamma-lyase, [5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methyl dihydrogen phosphate, TRIETHYLENE GLYCOL, ... (6 entities in total)
Functional Keywordsaminotransferase class i and ii, methionine, lyase
Biological sourceCitrobacter freundii
Total number of polymer chains1
Total molecular weight43816.06
Revtovich, S.V.,Nikulin, A.D.,Morozova, E.A.,Demidkina, T.V. (deposition date: 2014-01-27, release date: 2014-11-26, Last modification date: 2015-01-21)
Primary citation
Kuznetsov, N.A.,Faleev, N.G.,Kuznetsova, A.A.,Morozova, E.A.,Revtovich, S.V.,Anufrieva, N.V.,Nikulin, A.D.,Fedorova, O.S.,Demidkina, T.V.
Pre-steady-state Kinetic and Structural Analysis of Interaction of Methionine gamma-Lyase from Citrobacter freundii with Inhibitors.
J.Biol.Chem., 290:671-681, 2015
PubMed: 25398880 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M114.586511
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.19950.5%0.6%4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16