PDB: 149 件ウェブページステータス検索Chemie searchBIRD

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4XQ2	Ensemble refinement of cystathione gamma lyase (CalE6) D7G from Micromonospora echinospora 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, CalE6, ... 著者 Wang, F, Yennamalli, R.M, Singh, S, Tan, K, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2015-01-18 公開日 2015-04-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora To Be Published
6S0C	Crystal structure of methionine gamma-lyase from Citrobacter freundii modified by dimethylthiosulfinate 分子名称: Cystathionine gamma-synthase, PYRIDOXAL-5'-PHOSPHATE, TRIETHYLENE GLYCOL 著者 Revtovich, S.V, Morozova, E.A, Nikulin, A.D, Demidkina, T.V. 登録日 2019-06-14 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Sulfoxides of sulfur-containing amino acids are suicide substrates of Citrobacter freundii methionine gamma-lyase. Structural bases of the enzyme inactivation. Biochimie, 168, 2020
5M3Z	Crystal structure of Citrobacter freundii methionine gamma-lyase with C115H replacement in the complex with L-norleucine 分子名称: 2-[O-PHOSPHONOPYRIDOXYL]-AMINO-HEXANOIC ACID, Methionine gamma-lyase, NORLEUCINE, ... 著者 Revtovich, S.V, Nikulin, A.D, Anufrieva, N.V, Morozova, E.A, Demidkina, T.V. 登録日 2016-10-17 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of mutant form Cys115His of Citrobacter freundii methionine gamma-lyase complexed with l-norleucine. Biochim. Biophys. Acta, 1865, 2017
7YEO	Crystal Structure of cystathionine gamma-synthase-like protein C23A1.14c 分子名称: MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, Uncharacterized trans-sulfuration enzyme C23A1.14c 著者 Zhang, S.J. 登録日 2022-07-06 公開日 2023-01-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of cystathionine gamma-synthase-like protein C23A1.14c To Be Published
7SWH	Crystal Structure of Putative cystathionine gamma-synthase from Burkholderia pseudomallei in Complex with PLP 分子名称: 1,2-ETHANEDIOL, Putative cystathionine gamma-synthase 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-11-19 公開日 2021-12-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Putative cystathionine gamma-synthase from Burkholderia pseudomallei in Complex with PLP to be published
5X5H	Crystal structure of metB from Corynebacterium glutamicum 分子名称: Cystathionine beta-lyases/cystathionine gamma-synthases, GLYCEROL, MAGNESIUM ION, ... 著者 Sagong, H.-Y, Kim, K.-J. 登録日 2017-02-16 公開日 2017-03-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Structural Insights into Substrate Specificity of Cystathionine gamma-Synthase from Corynebacterium glutamicum J. Agric. Food Chem., 65, 2017
5X2X	Crystal structure of Pseudomonas putida methionine gamma-lyase wild type with L-homocysteine intermediates 分子名称: (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid, HYDROSULFURIC ACID, L-methionine gamma-lyase 著者 Shiba, T, Sato, D, Harada, S. 登録日 2017-02-02 公開日 2017-04-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and mechanistic insights into homocysteine degradation by a mutant of methionine gamma-lyase based on substrate-assisted catalysis Protein Sci., 26, 2017
6NBA	Crystal structure of Human Cystathionine gamma lyase with S-3-Carboxpropyl-L-Cysteine 分子名称: 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, Cystathionine gamma-lyase 著者 Kim, H, Yadav, P.K, Banerjee, R, Cho, U.-S. 登録日 2018-12-06 公開日 2019-06-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.495 Å) 主引用文献 S-3-Carboxypropyl-l-cysteine specifically inhibits cystathionine gamma-lyase-dependent hydrogen sulfide synthesis. J.Biol.Chem., 294, 2019
2FQ6	Cystathionine beta-lyase (cbl) from escherichia coli in complex with n-hydrazinocarbonylmethyl-2-trifluoromethyl-benzamide 分子名称: Cystathionine beta-lyase, PHOSPHORIC ACID MONO-(5-HYDROXY-6-METHYL-4-{[2-(2-TRIFLUOROMETHYL-BENZOYLAMINO)-ACETYL]-HYDRAZONOMETHYL}-PYRIDIN-3-YLMETHYL)ESTER 著者 Junop, M.S. 登録日 2006-01-17 公開日 2006-12-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function. J.Med.Chem., 50, 2007
6OVG	L-Methionine Depletion with an Engineered Human Enzyme Disrupts Prostate Cancer Metabolism 分子名称: Cystathionine gamma-lyase, SULFATE ION 著者 Yan, W, Irani, S, Zhang, J. 登録日 2019-05-07 公開日 2020-04-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.719 Å) 主引用文献 Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity. Proc.Natl.Acad.Sci.USA, 117, 2020
5IJG	Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution 分子名称: Cys/Met metabolism pyridoxal-phosphate-dependent enzyme, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE 著者 Boyko, K.M, Nikolaeva, A.Y, Koolikova, V.V, Kotlov, M.I, Demidkina, T.V, Popov, V.O. 登録日 2016-03-02 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution To Be Published
1UKJ	Detailed structure of L-Methionine-Lyase from Pseudomonas putida 分子名称: Methionine gamma-lyase, SULFATE ION 著者 Misaki, S, Takimoto, A, Takakura, T, Yoshioka, T, Yamashita, M, Tamura, T, Tanaka, H, Inagaki, K. 登録日 2003-08-24 公開日 2004-10-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Detailed structure of L-Methionine -Lyase from Pseudomonas putida To be Published
2GQN	Cystathionine Beta-Lyase (CBL) from Escherichia Coli in complex with N-Hydrazinocarbonylmethyl-2-Nitro-Benzamide 分子名称: (5-HYDROXY-6-METHYL-4-((2-(2-(2-NITROBENZAMIDO)ACETYL)HYDRAZINYL)METHYL)PYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Cystathionine beta-lyase 著者 Summerfield, R, Junop, M.S. 登録日 2006-04-21 公開日 2007-03-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Inhibitors of Bacterial Cystathionine beta-Lyase: Leads for New Antimicrobial Agents and Probes of Enzyme Structure and Function. J.Med.Chem., 50, 2007
5K30	Crystal structure of methionine gamma-lyase from Citrobacter freundii modified by S-Ethyl-L-cysteine sulfoxide 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, ... 著者 Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V. 登録日 2016-05-19 公開日 2017-07-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Sulfoxides of sulfur-containing amino acids are suicide substrates of Citrobacter freundii methionine gamma-lyase. Structural bases of the enzyme inactivation. Biochimie, 168, 2020
2CB1	Crystal Structure of O-actetyl Homoserine Sulfhydrylase From Thermus Thermophilus HB8,OAH2. 分子名称: O-ACETYL HOMOSERINE SULFHYDRYLASE, PYRIDOXAL-5'-PHOSPHATE 著者 Imagawa, T, Utsunomiya, H, Tsuge, H, Ebihara, A, Kanagawa, M, Nakagawa, N, Kuroishi, C, Agari, Y, Kuramitsu, S, Yokoyama, S. 登録日 2005-12-28 公開日 2007-01-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Crystal Structure of O-Acetyl Homoserine Sulfhydrylase To be Published
2CTZ	Crystal structure of o-acetyl homoserine sulfhydrylase from Thermus thermophilus HB8 分子名称: O-acetyl-L-homoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE 著者 Imagawa, T, Kousumi, Y, Tsuge, H, Utsunomiya, H, Ebihara, A, Nakagawa, N, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-24 公開日 2005-11-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of o-acetyl homoserine sulfhydrylase from Thermus thermophilus HB8 To be Published
1Y4I	Crystal structure of Citrobacter Freundii L-methionine-lyase 分子名称: SULFATE ION, methionine gamma-lyase 著者 Revtovich, S.V, Mamaeva, D.V, Morozova, E.A, Nikulin, A.D, Nikonov, S.V, Garber, M.B, Demidkina, T.V. 登録日 2004-12-01 公開日 2005-06-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of Citrobacter freundii L-methionine gamma-lyase. Acta Crystallogr.,Sect.F, 61, 2005
6CJA	Crystal structure of Cystathionine beta-lyase from Legionella pneumophila Philadelphia 1 in complex with Alanyl-PLP and Serine 分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-alanine, Cystathionine beta-lyase, GLYCEROL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-02-26 公開日 2018-03-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of Cystathionine beta-lyase from Legionella pneumophila Philadelphia 1 in complex with Alanyl-PLP and Serine to be published
6CJB	Crystal structure of Cystathionine beta-lyase from Legionella pneumophila Philadelphia 1 covalently bound to Pyridoxal phosphate 分子名称: Cystathionine beta-lyase, FORMIC ACID, GLYCEROL 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-02-26 公開日 2018-03-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of Cystathionine beta-lyase from Legionella pneumophila Philadelphia 1 covalently bound to Pyridoxal phosphate to be published
8ERB	Crystal structure of Fub7 in complex with vinylglycine ketimine 分子名称: (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, Sulfhydrylase FUB7 著者 Hai, Y. 登録日 2022-10-11 公開日 2023-10-18 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Molecular and Structural Basis for C gamma-C Bond Formation by PLP-Dependent Enzyme Fub7. Angew.Chem.Int.Ed.Engl., 63, 2024
8EQW	Crystal structure of Fub7 分子名称: Sulfhydrylase FUB7 著者 Hai, Y. 登録日 2022-10-10 公開日 2023-10-11 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Molecular and Structural Basis for C gamma-C Bond Formation by PLP-Dependent Enzyme Fub7. Angew.Chem.Int.Ed.Engl., 63, 2024
8ERJ	Crystal structure of Fub7 in complex with E-2-aminocrotonate 分子名称: (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid, (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]but-3-enoic acid, Sulfhydrylase FUB7 著者 Hai, Y. 登録日 2022-10-12 公開日 2023-10-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Molecular and Structural Basis for C gamma-C Bond Formation by PLP-Dependent Enzyme Fub7. Angew.Chem.Int.Ed.Engl., 63, 2024
4Q31	The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FORMIC ACID, ... 著者 Tan, K, Bigelow, L, Jedrzejczak, R, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2014-04-10 公開日 2014-05-07 最終更新日 2017-03-08 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate. Struct Dyn, 3, 2016
7BQW	Crystal structure of Methionine gamma-lyase from Fusobacterium nucleatum 分子名称: L-methionine gamma-lyase 著者 Lan, J, Chen, Y, Liu, W, Xu, Y. 登録日 2020-03-25 公開日 2020-04-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of Methionine gamma-lyase from Fusobacterium nucleatum To Be Published
7BA4	Structure of Cystathionine gamma-lyase from Pseudomonas aeruginosa 分子名称: Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE 著者 Fernandez-Rodriguez, C, Oyenarte, I, Gonzalez-Recio, I, Majtan, T, Astegno, A, Martinez-Cruz, L.A. 登録日 2020-12-15 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of Cystathionine gamma-lyase from Pseudomonas aeruginosa To Be Published

 

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