PDB: 294 件ウェブページステータス検索Chemie searchBIRD

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2EZS	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 31-40 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES 分子名称: GP41 著者 Caffrey, M, Gronenborn, A.M, Clore, G.M. 登録日 1998-05-20 公開日 1998-10-14 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
2EZR	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 21-30 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES 分子名称: GP41 著者 Caffrey, M, Gronenborn, A.M, Clore, G.M. 登録日 1998-05-20 公開日 1998-10-14 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
2EZO	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, RESTRAINED REGULARIZED MEAN STRUCTURE 分子名称: GP41 著者 Caffrey, M, Gronenborn, A.M, Clore, G.M. 登録日 1998-05-20 公開日 1998-10-14 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
2EZQ	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 11-20 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES 分子名称: GP41 著者 Caffrey, M, Gronenborn, A.M, Clore, G.M. 登録日 1998-05-20 公開日 1998-10-14 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
5HFM	Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail 分子名称: Envelope glycoprotein gp160,gp41 CHR region, TRIS(HYDROXYETHYL)AMINOMETHANE 著者 Zhu, Y, Ye, S, Zhang, R. 登録日 2016-01-07 公開日 2017-01-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.298 Å) 主引用文献 Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations Sci Rep, 6, 2016
5HFL	Gp41-targeting HIV-1 fusion inhibitors with helical Ile-Asp-Leu tail 分子名称: Envelope glycoprotein,gp41 CHR region 著者 Zhu, Y, Ye, S, Zhang, R. 登録日 2016-01-07 公開日 2017-01-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.294 Å) 主引用文献 Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations Sci Rep, 6, 2016
6R2G	Crystal structure of a single-chain protein mimetic of the gp41 NHR trimer in complex with the synthetic CHR peptide C34 分子名称: Envelope glycoprotein gp160, PHOSPHATE ION, Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 著者 Camara-Artigas, A, Conejero-Lara, F, Jurado, S, Cano-Munoz, M, Morel, B. 登録日 2019-03-17 公開日 2019-07-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins. J.Mol.Biol., 431, 2019
7T9B	ApexGT5 in complex with GT5-d42.16 and RM20A3 Fabs 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Berndsen, Z.T, Ward, A.B. 登録日 2021-12-18 公開日 2022-09-28 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (3.72 Å) 主引用文献 Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens Immunity, 2022
7T9A	ApexGT2 in complex with GT2-d42.16 and RM20A3 Fabs 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GT2-d42.16 Fab Heavy Chain, ... 著者 Berndsen, Z.T, Ward, A.B. 登録日 2021-12-18 公開日 2022-09-28 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens Immunity, 2022
6SNE	crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LN01 heavy chain, ... 著者 Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W. 登録日 2019-08-23 公開日 2019-11-06 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01. Cell Host Microbe, 26, 2019
6UJV	Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail (LLP2) 分子名称: Envelope glycoprotein GP41 著者 Piai, A, Fu, Q, Cai, Y, Ghantous, F, Xiao, T, Shaik, M.M, Peng, H, Rits-Volloch, S, Liu, Z, Chen, W, Seaman, M.S, Chen, B, Chou, J.J. 登録日 2019-10-03 公開日 2020-05-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein. Nat Commun, 11, 2020
8E1P	Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIP.v4.1-GT1.2gp120, ... 著者 Sarkar, A, Kumar, S, Wilson, I.A. 登録日 2022-08-11 公開日 2023-06-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.82 Å) 主引用文献 Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions. Cell Rep Med, 4, 2023
6NC3	AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env AMC011 v4.2 SOSIP gp120, ... 著者 Cottrell, C.A, Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2018-12-10 公開日 2019-06-19 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25, 2019
6NC2	AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 v4.2 SOSIP gp120, ... 著者 Cottrell, C.A, Ozorowski, G, Yuan, M, Copps, J, Wilson, I.A, Ward, A.B. 登録日 2018-12-10 公開日 2019-06-19 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25, 2019
7LOI	Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail 分子名称: Transmembrane protein gp41 著者 Piai, A, Fu, Q, Sharp, A.K, Bighi, B, Brown, A.M, Chou, J.J. 登録日 2021-02-10 公開日 2021-04-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology. J.Am.Chem.Soc., 143, 2021
7LXN	Cryo-EM structure of EDC-crosslinked ConM SOSIP.v7 (ConM-EDC) in complex with bNAb PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env glycoprotein gp120, ... 著者 Martin, G.M, Ward, A.B, Sattentau, Q.J. 登録日 2021-03-04 公開日 2022-03-09 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.85 Å) 主引用文献 Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens. Npj Vaccines, 8, 2023
4TVP	Crystal Structure of the HIV-1 BG505 SOSIP.664 Env Trimer Ectodomain, Comprising Atomic-Level Definition of Pre-Fusion gp120 and gp41, in Complex with Human Antibodies PGT122 and 35O22 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ... 著者 Pancera, M, Zhou, T, Kwong, P.D. 登録日 2014-06-27 公開日 2014-10-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure and immune recognition of trimeric pre-fusion HIV-1 Env. Nature, 514, 2014
7PC2	HIV-1 Env (BG505 SOSIP.664) in complex with the IgA bNAb 7-269 and the antibody 3BNC117. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC IgG Fab heavy chain, ... 著者 Fernandez, I, Bontems, F, Pehau-Arnaudet, G, Rey, F. 登録日 2021-08-03 公開日 2022-02-23 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller. J.Exp.Med., 219, 2022
7KDE	BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2020-10-08 公開日 2020-10-28 最終更新日 2020-11-04 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch. Elife, 9, 2020
6B0N	Crystal structure of the cleavage-independent prefusion HIV Env glycoprotein trimer of the clade A BG505 isolate (NFL construct) in complex with Fabs PGT122 and PGV19 at 3.39 A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp140, ... 著者 Sarkar, A, Irimia, A, Wilson, I.A. 登録日 2017-09-14 公開日 2018-05-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. Nat Commun, 9, 2018
5JS9	Uncleaved prefusion optimized gp140 trimer with an engineered 8-residue HR1 turn bound to broadly neutralizing antibodies 8ANC195 and PGT128 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kong, L, Wilson, I.A. 登録日 2016-05-07 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (6.918 Å) 主引用文献 Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability. Nat Commun, 7, 2016
5JSA	Uncleaved prefusion optimized gp140 trimer with an engineered 10-residue HR1 turn bound to broadly neutralizing antibodies 8ANC195 and PGT128 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kong, L, Wilson, I.A. 登録日 2016-05-07 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (6.308 Å) 主引用文献 Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability. Nat Commun, 7, 2016
7UGP	Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 containing the N276 gp120 glycan- Class 1 分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Dam, K.A, Bjorkman, P.J. 登録日 2022-03-25 公開日 2022-11-09 最終更新日 2022-11-16 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13, 2022
7UGO	Cryo-EM structure of BG24 inferred germline Fabs with mature CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Dam, K.A, Bjorkman, P.J. 登録日 2022-03-25 公開日 2022-10-26 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13, 2022
7UGN	Cryo-EM structure of BG24 inferred germline Fabs with germline CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 - Class 1 分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Dam, K.A, Bjorkman, P.J. 登録日 2022-03-25 公開日 2022-10-26 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13, 2022

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