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7TFN	Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-HIV-1 CD4bs antibody Fab Ab1303 - Heavy chain, ... Authors: Yang, Z, Bjorkman, P.J. Deposit date: 2022-01-06 Release date: 2022-01-19 Last modified: 2022-02-23 Method: ELECTRON MICROSCOPY (4 Å) Cite: Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13, 2022
7TFO	Cryo-EM structure of HIV-1 Env trimer BG505 SOSIP.664 in complex with CD4bs antibody Ab1573 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4 binding site antibody Ab1573 - Fab heavy chain, ... Authors: Yang, Z, Bjorkman, P.J. Deposit date: 2022-01-06 Release date: 2022-01-26 Last modified: 2022-02-23 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13, 2022
7MDU	BG505 SOSIP MD39 in complex with the monoclonal antibodies Rh.33104 mAb.1 and RM20A3 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RM20A3 mAb Heavy Chain, ... Authors: Antanasijevic, A, Ward, A.B. Deposit date: 2021-04-06 Release date: 2022-01-26 Last modified: 2022-02-02 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
7MDT	BG505 SOSIP.v5.2 in complex with the monoclonal antibody Rh4O9.8 (as Fab fragment) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rh4O9.8 monoclonal antibody Heavy Chain, ... Authors: Antanasijevic, A, Ozorowski, G, Nogal, B, Ward, A.B. Deposit date: 2021-04-06 Release date: 2022-01-26 Last modified: 2022-02-02 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
7MEP	BG505 SOSIP.v5.2(7S) in complex with the monoclonal antibodies Rh.33172 mAb.1 and RM19R Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2(7S) - gp120, ... Authors: Antanasijevic, A, Ward, A.B. Deposit date: 2021-04-07 Release date: 2022-01-26 Last modified: 2022-08-10 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
7PC2	HIV-1 Env (BG505 SOSIP.664) in complex with the IgA bNAb 7-269 and the antibody 3BNC117. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC IgG Fab heavy chain, ... Authors: Fernandez, I, Bontems, F, Pehau-Arnaudet, G, Rey, F. Deposit date: 2021-08-03 Release date: 2022-02-23 Last modified: 2022-03-16 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller. J.Exp.Med., 219, 2022
7LPN	Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2021-02-12 Release date: 2022-02-23 Last modified: 2023-03-29 Method: ELECTRON MICROSCOPY (3.61 Å) Cite: Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7SKA	Sub-tomogram averaged structure of HIV-1 Envelope protein in native membrane Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(2-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Mangala Prasad, V, Lee, K.K. Deposit date: 2021-10-20 Release date: 2022-03-09 Method: ELECTRON MICROSCOPY (9.1 Å) Cite: Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice. Cell, 185, 2022
7RI1	Crystal structure of anti-HIV llama VHH antibody J3 in complex with HIV-1 C1086 gp120 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Lamma VHH antibody J3, ... Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-07-19 Release date: 2022-03-30 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7RI2	Crystal structure of anti-HIV llama VHH antibody A12 in complex with HIV-1 C1086 gp120 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, anti-HIV llama VHH antibody A12 Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-07-19 Release date: 2022-03-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7R73	Crystal structure of llama VHH antibody D7 in complex with HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Llama antibody D7 Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-06-24 Release date: 2022-03-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7R74	Crystal structure of llama VHH antibody in complex with HIV-1 HXBC2 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C8 VHH domain, Glycoprotein 120 Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-06-24 Release date: 2022-03-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7MXD	Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J038 in complex with HIV-1 Env Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody heavy chain, ... Authors: Zhou, T, Gao, F. Deposit date: 2021-05-19 Release date: 2022-03-30 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2. Adv Sci, 9, 2022
7N28	Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J033 in complex with HIV-1 Env Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody heavy chain, ... Authors: Zhou, T, Gao, F. Deposit date: 2021-05-28 Release date: 2022-04-06 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2. Adv Sci, 9, 2022
7N8Q	Rhesusized RV305 DH677.3 Fab bound to Clade A/E 93TH057 HIV-1 gp120 core. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, M48U1 CD4 MIMETIC PEPTIDE, Rhesusized DH677.3 FAB HEAVY CHAIN, ... Authors: Tolbert, W.D, Pazgier, M. Deposit date: 2021-06-15 Release date: 2022-04-06 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s. Front Immunol, 12, 2021
7RDW	Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... Authors: Weidle, C, Pancera, M. Deposit date: 2021-07-12 Release date: 2022-05-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.55 Å) Cite: Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain. Sci Adv, 8, 2022
7SQ1	BG505.MD39TS Env trimer in complex with Fab from antibody C05 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C05 Fab Light chain, ... Authors: Moore, A, Du, J, Xu, Z, Walker, S, Kulp, D.W, Pallesen, J. Deposit date: 2021-11-04 Release date: 2022-06-22 Last modified: 2022-12-07 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer. Nat Commun, 13, 2022
7UCG	Structure of the DU422 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24 Descriptor: 10-1074 Fab heavy chain, 10-1074 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Barnes, C.O, Bjorkman, P.J. Deposit date: 2022-03-16 Release date: 2022-08-17 Last modified: 2022-09-07 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: A naturally arising broad and potent CD4-binding site antibody with low somatic mutation. Sci Adv, 8, 2022
7UCF	Structure of the BG505 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24 Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Barnes, C.O, Bjorkman, P.J. Deposit date: 2022-03-16 Release date: 2022-08-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4 Å) Cite: A naturally arising broad and potent CD4-binding site antibody with low somatic mutation. Sci Adv, 8, 2022
7T2P	The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2021-12-06 Release date: 2022-10-19 Last modified: 2023-07-05 Method: ELECTRON MICROSCOPY (3.47 Å) Cite: Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus. Nat Commun, 13, 2022
7T4G	The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2021-12-09 Release date: 2022-10-19 Last modified: 2023-07-05 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus. Nat Commun, 13, 2022
7UGO	Cryo-EM structure of BG24 inferred germline Fabs with mature CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Dam, K.A, Bjorkman, P.J. Deposit date: 2022-03-25 Release date: 2022-10-26 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13, 2022
7UGN	Cryo-EM structure of BG24 inferred germline Fabs with germline CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 - Class 1 Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Dam, K.A, Bjorkman, P.J. Deposit date: 2022-03-25 Release date: 2022-10-26 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13, 2022
8DUA	SIV E660.CR54 SOS-2P Env Trimer with ITS92.02 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Envelope glycoprotein gp41, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2022-07-27 Release date: 2022-10-26 Last modified: 2022-11-30 Method: ELECTRON MICROSCOPY (4.32 Å) Cite: Cryo-EM structures of prefusion SIV envelope trimer. Nat.Struct.Mol.Biol., 29, 2022
7UGP	Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 containing the N276 gp120 glycan- Class 1 Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Dam, K.A, Bjorkman, P.J. Deposit date: 2022-03-25 Release date: 2022-11-09 Last modified: 2022-11-16 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13, 2022

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