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6D7U	The crystal structure of hemagglutinin from A/Guangdong/17SF003/2016 H7N9 influenza virus Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain Authors: Yang, H, Stevens, J. Deposit date: 2018-04-25 Release date: 2018-05-30 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural and Molecular Characterization of the Hemagglutinin from the Fifth-Epidemic-Wave A(H7N9) Influenza Viruses. J. Virol., 92, 2018
6D7C	The crystal structure of hemagglutinin from A/Hong Kong/61/2016 H7N9 influenza virus Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain Authors: Yang, H, Stevens, J. Deposit date: 2018-04-24 Release date: 2018-05-30 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structural and Molecular Characterization of the Hemagglutinin from the Fifth-Epidemic-Wave A(H7N9) Influenza Viruses. J. Virol., 92, 2018
6D0U	Crystal structure of C05 V110P/A117E mutant bound to H3 influenza hemagglutinin, HA1 subunit Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05 V110P/A117E mutant, heavy chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2018-04-11 Release date: 2019-01-16 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6FYT	Structure of H1 (A/solomon Islands/3/06) Influenza Hemagglutinin in complex with SD38 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Laursen, N.S, Wilson, I.A. Deposit date: 2018-03-12 Release date: 2018-11-07 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science, 362, 2018
6FYW	Structure of B/Brisbane/60/2008 Influenza Hemagglutinin in complex with SD83 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... Authors: Laursen, N.S, Wilson, I.A. Deposit date: 2018-03-12 Release date: 2018-11-07 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science, 362, 2018
6FYU	Structure of H7(A/Shanghai/2/2013) Influenza Hemagglutinin in complex SD36 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Laursen, N.S, Wilson, I.A. Deposit date: 2018-03-12 Release date: 2018-11-07 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.643 Å) Cite: Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science, 362, 2018
6CNV	INFLUENZA B/BRISBANE HEMAGGLUTININ FAB CR9115 SD84H COMPLEX Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 Fab heavy chain, ... Authors: Luo, J, Obmolova, G. Deposit date: 2018-03-09 Release date: 2018-11-14 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science, 362, 2018
6CHX	High Resolution Crystal Structure of the Hemagglutinin H1 Head Domain of Influenza A virus Solomon Islands Descriptor: Hemagglutinin Authors: Dong, J, Sevy, A.M, Crowe, J.E. Deposit date: 2018-02-23 Release date: 2019-02-27 Method: X-RAY DIFFRACTION (1.4 Å) Cite: High Resolution Crystal Structure of the Hemagglutinin H1 Head Domain of Influenza A virus Solomon Islands To Be Published
6CFG	Crystal structure of the A/Vietnam/1203/2004 (H5N1) influenza virus hemagglutinin in complex with small molecule JNJ4796 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... Authors: Kadam, R.U, Wilson, I.A. Deposit date: 2018-02-14 Release date: 2019-02-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.32 Å) Cite: A small-molecule fusion inhibitor of influenza virus is orally active in mice. Science, 363, 2019
6CF5	Crystal structure of the A/Viet Nam/1203/2004(H5N1) influenza virus hemagglutinin in complex with small molecule N-Cyclohexyltaurine Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wilson, I.A, Kadam, R.U. Deposit date: 2018-02-13 Release date: 2018-04-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.04 Å) Cite: A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CF7	Crystal structure of the A/Solomon Islands/3/2006(H1N1) influenza virus hemagglutinin in complex with small molecule JNJ4796 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Kadam, R.U, Wilson, I.A. Deposit date: 2018-02-13 Release date: 2019-02-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.719 Å) Cite: A small-molecule fusion inhibitor of influenza virus is orally active in mice. Science, 363, 2019
6CEX	Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin in complex with small molecule N-Cyclohexyltaurine Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: wilson, I.A, Kadam, R.U. Deposit date: 2018-02-12 Release date: 2018-04-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.57 Å) Cite: A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YT9	Crystal structure of H5 hemagglutinin G228S mutant from A/chicken/Taiwan/0502/2012 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Lin, T.H, Lee, M.S, Wu, W.G, Liu, J.S. Deposit date: 2017-11-17 Release date: 2018-11-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.766 Å) Cite: crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012 To Be Published
5YT8	Crystal structure of H5 hemagglutinin with G228S Q226L mutants from A/chicken/Taiwan/0502/2012 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Lin, T.H, Lee, M.S, Wu, W.G, Liu, J.S. Deposit date: 2017-11-17 Release date: 2018-11-21 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.765 Å) Cite: crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012 To Be Published
6BKQ	Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin E190D mutant in complex with 6'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.25 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKO	Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin D190E mutant apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKS	Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin D190E mutant in complex with 6'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKR	Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin in complex with 6'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.76 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKT	Crystal structure of the A/Michigan/15/2014 (H3N2) influenza virus hemagglutinin in complex with 6'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKM	Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin E190D mutant apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKP	Crystal structure of the A/Michigan/15/2014 (H3N2) influenza virus hemagglutinin apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.05 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
6BKN	Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-11-09 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018
5YKC	crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Lin, T.H, Lee, M.S, Wu, W.G. Deposit date: 2017-10-13 Release date: 2018-10-17 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.823 Å) Cite: crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012 To Be Published
6B3M	The crystal structure of a broadly-reactive human anti-hemagglutinin stalk antibody (70-1F02) in complex with H5 hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 70-1F02 Fab Heavy Chain, ... Authors: Shore, D.A, Yang, H, Stevens, J. Deposit date: 2017-09-22 Release date: 2018-06-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.92 Å) Cite: Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. J. Virol., 92, 2018
6AOP	Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant apo form Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Wilson, I.A. Deposit date: 2017-08-16 Release date: 2017-10-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017

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