PDB: 161 件ウェブページステータス検索Chemie searchBIRD

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5EJS	Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain, mutant 1 分子名称: Myosin-I heavy chain 著者 Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2015-11-02 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Myosin MyTH4-FERM structures highlight important principles of convergent evolution. Proc.Natl.Acad.Sci.USA, 113, 2016
2AL6	FERM domain of Focal Adhesion Kinase 分子名称: Focal adhesion kinase 1 著者 Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J. 登録日 2005-08-04 公開日 2005-10-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structure of the FERM Domain of Focal Adhesion Kinase J.Biol.Chem., 281, 2006
8CIT	The FERM domain of human moesin mutant L281R 分子名称: Moesin 著者 Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.536 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
8CIR	The FERM domain of human moesin with a bound peptide identified by phage display 分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, ... 著者 Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
8CIS	The FERM domain of human moesin with two bound peptides identified by phage display 分子名称: 1,2-ETHANEDIOL, ACETATE ION, C3P, ... 著者 Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
8CIU	The FERM domain of human moesin mutant H288A 分子名称: Moesin 著者 Bradshaw, W.J, Katis, V.L, Koekemoer, L, Bountra, C, von Delft, F, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.393 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
3PZD	Structure of the myosin X MyTH4-FERM/DCC complex 分子名称: GLYCEROL, Myosin-X, Netrin receptor DCC 著者 Wei, Z, Yan, J, Pan, L, Zhang, M. 登録日 2010-12-14 公開日 2011-02-23 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain Proc.Natl.Acad.Sci.USA, 108, 2011
3WA0	Crystal structure of merlin complexed with DCAF1/VprBP 分子名称: Merlin, Protein VPRBP 著者 Mori, T, Gotoh, S, Shirakawa, M, Hakoshima, T. 登録日 2013-04-20 公開日 2014-05-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function. Genes Cells, 19, 2014
3QIJ	Primitive-monoclinic crystal structure of the FERM domain of protein 4.1R 分子名称: Protein 4.1, UNKNOWN ATOM OR ION 著者 Nedyalkova, L, Zhong, N, Tong, Y, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) 登録日 2011-01-27 公開日 2011-02-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Primitive-monoclinic crystal structure of the FERM domain of protein 4.1R to be published
3X23	Radixin complex 分子名称: Peptide from Matrix metalloproteinase-14, Radixin 著者 Terawaki, S, Kitano, K, Aoyama, M, Mori, T, Hakoshima, T. 登録日 2014-12-09 公開日 2015-10-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.396 Å) 主引用文献 MT1-MMP recognition by ERM proteins and its implication in CD44 shedding Genes Cells, 20, 2015
4YL8	Crystal structure of the Crumbs/Moesin complex 分子名称: GLYCEROL, IODIDE ION, Moesin, ... 著者 Wei, Z, Li, Y, Zhang, M. 登録日 2015-03-05 公開日 2015-04-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Basis for the Phosphorylation-regulated Interaction between the Cytoplasmic Tail of Cell Polarity Protein Crumbs and the Actin-binding Protein Moesin J.Biol.Chem., 290, 2015
3ZDT	Crystal structure of basic patch mutant FAK FERM domain FAK31- 405 K216A, K218A, R221A, K222A 分子名称: FOCAL ADHESION KINASE 1 著者 Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D. 登録日 2012-11-30 公開日 2012-12-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes. Proc.Natl.Acad.Sci.USA, 111, 2014
6QLY	IDOL FERM domain 分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase MYLIP, SULFATE ION 著者 Martinelli, L, Sixma, T.K. 登録日 2019-02-01 公開日 2020-02-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site. J.Biol.Chem., 295, 2020
6R9T	Cryo-EM structure of autoinhibited human talin-1 分子名称: Talin-1 著者 Dedden, D, Schumacher, S, Zacharias, M, Biertumpfel, C, Mizuno, N. 登録日 2019-04-04 公開日 2019-10-16 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 The Architecture of Talin1 Reveals an Autoinhibition Mechanism. Cell, 179, 2019
4ZRK	Merlin-FERM and Lats1 complex 分子名称: Merlin, Serine/threonine-protein kinase LATS1 著者 Lin, Z, Li, Y, Wei, Z, Zhang, M. 登録日 2015-05-12 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.316 Å) 主引用文献 Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
4ZRI	Crystal structure of Merlin-FERM and Lats2 分子名称: Merlin, Serine/threonine-protein kinase LATS2 著者 Li, F, Zhou, H, Long, J, Shen, Y. 登録日 2015-05-12 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
4ZRJ	Structure of Merlin-FERM and CTD 分子名称: GLYCEROL, Merlin 著者 Lin, Z, Li, F, Long, J, Shen, Y. 登録日 2015-05-12 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
5MV7	Structure of human Myosin 7b C-terminal MyTH4-FERM MF2 domain 分子名称: SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Unconventional myosin-VIIb 著者 Planelles-Herrero, V.J, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-15 公開日 2017-07-05 最終更新日 2022-03-30 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV8	Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain 分子名称: GLYCEROL, MAGNESIUM ION, Unconventional myosin-VIIb, ... 著者 Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-16 公開日 2017-07-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV9	Structure of human Myosin 7a C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain 分子名称: ACETATE ION, Unconventional myosin-VIIa, cDNA FLJ51329, ... 著者 Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-16 公開日 2017-07-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
3U8Z	human merlin FERM domain 分子名称: Merlin 著者 Yogesha, S.D, Sharff, A.J, Giovannini, M, Bricogne, G, Izard, T. 登録日 2011-10-17 公開日 2011-11-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor. Protein Sci., 20, 2011
4NY0	Crystal structure of FERM domain of human focal adhesion kinase 分子名称: Focal adhesion kinase 1 著者 Walkiewicz, K, Arold, S.T. 登録日 2013-12-10 公開日 2014-03-12 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 FAK dimerization controls its kinase-dependent functions at focal adhesions. Embo J., 33, 2014
6CB0	Crystal Structure of the FAK FERM domain 分子名称: Focal adhesion kinase 1 著者 Dementiev, A, Marlowe, T. 登録日 2018-02-01 公開日 2019-02-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 High resolution crystal structure of the FAK FERM domain reveals new insights on the Druggability of tyrosine 397 and the Src SH3 binding site. BMC Mol Cell Biol, 20, 2019
6CDS	Human neurofibromin 2/merlin/schwannomin residues 1-339 in complex with PIP2 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Merlin, ... 著者 Chinthalapudi, K, Sharff, A.J, Bricogne, G, Izard, T. 登録日 2018-02-09 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2. Nat Commun, 9, 2018
5XBF	Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3 分子名称: ACETATE ION, D-MALATE, GLYCEROL, ... 著者 Li, J, He, Y, Weck, W.L, Lu, Q, Tyska, M.J, Zhang, M. 登録日 2017-03-17 公開日 2017-05-17 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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