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2RQ1
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Solution structure of the 4.1R FERM alpha lobe domain
分子名称: Protein 4.1
著者Kusunoki, H, Kohno, T.
登録日2009-01-09
公開日2009-04-14
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure and glycophorin C binding studies of the protein 4.1R FERM alpha-lobe domain
Proteins, 76, 2009
1Y19
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Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
分子名称: Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1
著者de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C.
登録日2004-11-17
公開日2005-01-04
最終更新日2016-11-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
3U7D
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BU of 3u7d by Molmil
Crystal structure of the KRIT1/CCM1 FERM domain in complex with the heart of glass (HEG1) cytoplasmic tail
分子名称: Krev interaction trapped protein 1, Protein HEG homolog 1
著者Gingras, A.R, Liu, J.J, Ginsberg, M.H, Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions (CELLMAT)
登録日2011-10-13
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.
J.Cell Biol., 199, 2012
1MK7
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
分子名称: Integrin Beta3, TALIN
著者Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
登録日2002-08-28
公開日2003-01-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1MIX
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BU of 1mix by Molmil
Crystal structure of a FERM domain of Talin
分子名称: Talin
著者Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
登録日2002-08-23
公開日2003-01-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MK9
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BU of 1mk9 by Molmil
CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
分子名称: Integrin Beta3, TALIN
著者Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
登録日2002-08-28
公開日2003-01-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1MIZ
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BU of 1miz by Molmil
Crystal structure of an integrin beta3-talin chimera
分子名称: TALIN, integrin beta3
著者Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
登録日2002-08-23
公開日2003-01-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
4F7G
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Crystal structure of talin autoinhibition complex
分子名称: Talin-1
著者Song, X, Qin, J, Ye, S, Zhang, R.
登録日2012-05-16
公開日2012-07-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
Cell Res., 22, 2012
2HRJ
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BU of 2hrj by Molmil
NMR solution structure of the F2 subdomain of talin
分子名称: Talin-1
著者Liu, G, Arroyo, M.M, Zheng, J.
登録日2006-07-20
公開日2008-04-29
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structural characterization of the talin F2 FERM subdomain with Coenzyme A and PI(4,5)P2
To be Published
1SGH
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BU of 1sgh by Molmil
Moesin FERM domain bound to EBP50 C-terminal peptide
分子名称: Ezrin-radixin-moesin binding phosphoprotein 50, Moesin
著者Finnerty, C.M, Chambers, D, Ingraffea, J, Faber, H.R, Karplus, P.A, Bretscher, A.
登録日2004-02-23
公開日2004-06-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain
J.Cell.Sci., 117, 2004
6MFS
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BU of 6mfs by Molmil
Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2)
分子名称: PHOSPHATE ION, Talin-1 fusion, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Izard, T, Chinthalapudi, K, Rangarajan, E.S.
登録日2018-09-12
公開日2018-09-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7LWH
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BU of 7lwh by Molmil
Human neurofibromin 2/merlin residues 1-339 in complex with LATS1
分子名称: GLYCEROL, IMIDAZOLE, Merlin, ...
著者Primi, M.C, Rangarajan, E.S, Izard, T.
登録日2021-03-01
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.606 Å)
主引用文献Conformational flexibility determines the Nf2/merlin tumor suppressor functions.
Matrix Biol Plus, 12, 2021
6IBE
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BU of 6ibe by Molmil
The FERM domain of Human EPB41L3
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Band 4.1-like protein 3
著者Bradshaw, W.J, Katis, V.L, Newman, J.A, Fernandez-Cid, A, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2018-11-29
公開日2018-12-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The FERM domain of Human EPB41L3
To Be Published
7BYJ
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BU of 7byj by Molmil
Crystal structure of the FERM domain of FRMPD4
分子名称: FERM and PDZ domain-containing protein 4
著者Lin, L, Wang, M, Wang, C, Zhu, J.
登録日2020-04-23
公開日2020-12-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structure of the FERM domain of a neural scaffold protein FRMPD4 implicated in X-linked intellectual disability.
Biochem.J., 477, 2020
1EF1
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BU of 1ef1 by Molmil
CRYSTAL STRUCTURE OF THE MOESIN FERM DOMAIN/TAIL DOMAIN COMPLEX
分子名称: MOESIN, SULFATE ION
著者Pearson, M.A, Reczek, D, Bretscher, A, Karplus, P.A.
登録日2000-02-04
公開日2000-05-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain.
Cell(Cambridge,Mass.), 101, 2000
6VGU
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BU of 6vgu by Molmil
Crystal structure of FERM-folded talin head domain bound to the NPLY motif of beta3-integrin
分子名称: Integrin beta-3,Talin-1
著者Zhang, P, Sun, Y, Wu, J.
登録日2020-01-09
公開日2020-12-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding.
Proc.Natl.Acad.Sci.USA, 117, 2020
8GVL
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BU of 8gvl by Molmil
PTPN21 FERM
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Tyrosine-protein phosphatase non-receptor type 21
著者Chen, L, Zheng, Y.Y, Zhou, C.
登録日2022-09-15
公開日2023-09-20
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
7EDR
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BU of 7edr by Molmil
The crystal structure of the FERM and C-terminal domain complex of Drosophila Merlin
分子名称: Moesin/ezrin/radixin homolog 2
著者Zhang, F, Long, J, Zhou, H.
登録日2021-03-16
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.527 Å)
主引用文献The crystal structure of the FERM and C-terminal domain complex of Drosophila Merlin.
Biochem.Biophys.Res.Commun., 553, 2021
6XTJ
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BU of 6xtj by Molmil
The high resolution structure of the FERM domain of human FERMT2
分子名称: CITRIC ACID, Fermitin family homolog 2,Fermitin family homolog 2,Fermitin family homolog 2
著者Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2020-01-16
公開日2020-02-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The high resolution structure of the FERM domain of human FERMT2
To Be Published
3G9W
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BU of 3g9w by Molmil
Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ...
著者Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D.
登録日2009-02-15
公開日2009-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.165 Å)
主引用文献The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
3IVF
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BU of 3ivf by Molmil
Crystal structure of the talin head FERM domain
分子名称: Talin-1
著者Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
登録日2009-09-01
公開日2010-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
2J0K
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Crystal structure of a fragment of focal adhesion kinase containing the FERM and kinase domains.
分子名称: 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1
著者Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J.
登録日2006-08-03
公開日2007-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Autoinhibition of Focal Adhesion Kinase.
Cell(Cambridge,Mass.), 129, 2007
2J0M
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Crystal structure a two-chain complex between the FERM and kinase domains of focal adhesion kinase.
分子名称: 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1
著者Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J.
登録日2006-08-03
公開日2007-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Autoinhibition of Focal Adhesion Kinase.
Cell(Cambridge,Mass.), 129, 2007
5EJR
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BU of 5ejr by Molmil
Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain
分子名称: 1,2-ETHANEDIOL, Myosin-I heavy chain
著者Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Clause, J, Titus, M.A, Houdusse, A.
登録日2015-11-02
公開日2016-07-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Myosin MyTH4-FERM structures highlight important principles of convergent evolution.
Proc.Natl.Acad.Sci.USA, 113, 2016
2AEH
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Focal adhesion kinase 1
分子名称: Focal adhesion kinase 1
著者Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J.
登録日2005-07-22
公開日2005-10-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006

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