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3HJD
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X-ray structure of monomeric variant of HNP1
Descriptor: Human neutrophil peptide 1
Authors:Lubkowski, J, Pazgier, M, Lu, W.
Deposit date:2009-05-21
Release date:2009-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:What Dictates the Multifaced Functions of the Human alpha-Defensin HNP?
To be Published
2K1I
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Synthesis, Structure and Activities of an Oral Mucosal Alpha-Defensin from Rhesus Macaque
Descriptor: Mucosal Alpha-Defensin
Authors:Vasudevan, S.V, Yuan, J, Osapay, G, Tran, P, Tai, K, Selsted, M, Cocco, M.J.
Deposit date:2008-03-05
Release date:2008-10-28
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Synthesis, structure, and activities of an oral mucosal alpha-defensin from rhesus macaque.
J.Biol.Chem., 283, 2008
2KHT
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BU of 2kht by Molmil
NMR Structure of human alpha defensin HNP-1
Descriptor: Neutrophil defensin 1
Authors:Zhang, Y, Li, S, Doherty, T.F, Lubkowski, J, Lu, W, Li, J, Barinka, C, Hong, M.
Deposit date:2009-04-11
Release date:2010-02-09
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Resonance assignment and three-dimensional structure determination of a human alpha-defensin, HNP-1, by solid-state NMR.
J.Mol.Biol., 397, 2010
2MIT
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BU of 2mit by Molmil
Solution structure of oxidized dimeric form of human defensin 5
Descriptor: Defensin-5
Authors:Wommack, A.J, Ziarek, J.J, Wagner, G, Nolan, E.M.
Deposit date:2013-12-19
Release date:2014-09-17
Method:SOLUTION NMR
Cite:Solution structure of oxidized dimeric form of human defensin 5
To be Published
2LXZ
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Solution Structure of the Antimicrobial Peptide Human Defensin 5
Descriptor: Defensin-5
Authors:Wommack, A.J, Robson, S.A, Wanniarahchi, Y.A, Wan, A, Turner, C.J, Nolan, E.M.
Deposit date:2012-09-10
Release date:2012-11-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR solution structure and condition-dependent oligomerization of the antimicrobial Peptide human defensin 5.
Biochemistry, 51, 2012
2MXQ
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The solution structure of DEFA1, a highly potent antimicrobial peptide from the horse
Descriptor: Paneth cell-specific alpha-defensin 1
Authors:Jung, S, Michalek, M, Shomali, M, Soennichsen, F.D.
Deposit date:2015-01-12
Release date:2015-04-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure and functional studies of the highly potent equine antimicrobial peptide DEFA1.
Biochem.Biophys.Res.Commun., 459, 2015
1ZMH
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Crystal structure of human neutrophil peptide 2, HNP-2 (variant Gly16-> D-Ala)
Descriptor: GLYCEROL, HEXAETHYLENE GLYCOL, Neutrophil defensin 2, ...
Authors:Lubkowski, J, Prahl, A, Lu, W.
Deposit date:2005-05-10
Release date:2005-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
J.Biol.Chem., 280, 2005
1ZMI
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Crystal structure of human alpha_defensin-2 (variant GLY16->D-ALA), P 32 2 1 space group )
Descriptor: GLYCEROL, Neutrophil defensin 2, SULFATE ION
Authors:Lubkowski, J, Prahl, A, Lu, W.
Deposit date:2005-05-10
Release date:2005-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
J.Biol.Chem., 280, 2005
1ZMM
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Crystal structure of human alpha-defensin-4
Descriptor: Neutrophil defensin 4
Authors:Lubkowski, J, Szyk, A, Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
1ZMK
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Crystal structure of human alpha-defensin-2 (variant Gly16-> D-ALA), P 42 21 2 space group
Descriptor: CHLORIDE ION, GLYCEROL, Neutrophil defensin 2
Authors:Lubkowski, J, Prahl, A, Lu, W.
Deposit date:2005-05-10
Release date:2005-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
J.Biol.Chem., 280, 2005
1ZMP
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Crystal structure of human defensin-5
Descriptor: CHLORIDE ION, Defensin 5, GLYCEROL, ...
Authors:Lubkowski, J, Szyk, A, Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
1ZMQ
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Crystal structure of human alpha-defensin-6
Descriptor: CHLORIDE ION, Defensin 6
Authors:Lubkowski, J, Szyk, A, Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
3I5W
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BU of 3i5w by Molmil
Crystal structure of human alpha-defensin 5 (mutant R13H)
Descriptor: CHLORIDE ION, CITRATE ANION, Defensin-5
Authors:Pazgier, M, Lu, W.
Deposit date:2009-07-06
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5
Febs Lett., 583, 2009
3LO2
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Crystal structure of human alpha-defensin 1 (Y21A mutant)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Neutrophil defensin 1, SULFATE ION, ...
Authors:Pazgier, M, Lu, W.
Deposit date:2010-02-03
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LO1
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Crystal structure of human alpha-defensin 1 (Y16A mutant)
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, AZIDE ION, Neutrophil defensin 1
Authors:Pazgier, M, Lu, W.
Deposit date:2010-02-03
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LOE
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BU of 3loe by Molmil
Crystal structure of human alpha-defensin 1 (F28A mutant)
Descriptor: GLYCEROL, Neutrophil defensin 1, SULFATE ION
Authors:Pazgier, M, Lu, W.
Deposit date:2010-02-03
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LO4
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BU of 3lo4 by Molmil
Crystal structure of human alpha-defensin 1 (R24A mutant)
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Neutrophil defensin 1
Authors:Pazgier, M, Lu, W.
Deposit date:2010-02-03
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LO6
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BU of 3lo6 by Molmil
Crystal structure of human alpha-defensin 1 (W26Aba mutant)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Neutrophil defensin 1
Authors:Pazgier, M, Lu, W.
Deposit date:2010-02-03
Release date:2010-03-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LO9
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Crystal structure of human alpha-defensin 1 (W26Ahp mutant)
Descriptor: Neutrophil defensin 1
Authors:Pazgier, M, Lu, W.
Deposit date:2010-02-03
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
3LVX
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Crystal structure of human alpha-defensin 1 (I6A mutant)
Descriptor: GLYCEROL, Neutrophil defensin 1, SULFATE ION
Authors:Pazgier, M, Lu, W.
Deposit date:2010-02-22
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Trp-26 imparts functional versatility to human alpha-defensin HNP1.
J.Biol.Chem., 285, 2010
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